1,2,3,4-tetrahydroisoquinoline has been researched along with 3-methyl-1,2,3,4-tetrahydroisoquinoline in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grunewald, GL; Monn, JA; Sall, DJ | 2 |
| Ching, P; Criscione, KR; Dahanukar, VH; Grunewald, GL | 1 |
| Criscione, KR; Dahanukar, VH; Grunewald, GL; Teoh, B | 1 |
| Caldwell, TM; Criscione, KR; Grunewald, GL; Li, Q | 1 |
| Caldwell, TM; Criscione, KR; Dahanukar, VH; Grunewald, GL; Li, Q; McNeil, B | 1 |
| Bhat, SR; Criscione, KR; Grunewald, GL; Seim, MR; Wilson, ME | 1 |
7 other study(ies) available for 1,2,3,4-tetrahydroisoquinoline and 3-methyl-1,2,3,4-tetrahydroisoquinoline
| Article | Year |
|---|---|
Conformational and steric aspects of the inhibition of phenylethanolamine N-methyltransferase by benzylamines.
Topics: Benzylamines; Binding Sites; Isoquinolines; Molecular Conformation; Phenylethanolamine N-Methyltransferase; Structure-Activity Relationship; Tetrahydroisoquinolines | 1988 |
Synthesis and evaluation of 3-substituted analogues of 1,2,3,4-tetrahydroisoquinoline as inhibitors of phenylethanolamine N-methyltransferase.
Topics: Chemical Phenomena; Chemistry; Epinephrine; Isoquinolines; Phenylethanolamine N-Methyltransferase; Structure-Activity Relationship; Tetrahydroisoquinolines | 1988 |
Effect of ring size or an additional heteroatom on the potency and selectivity of bicyclic benzylamine-type inhibitors of phenylethanolamine N-methyltransferase.
Topics: Animals; Benzylamines; Enzyme Inhibitors; Male; Phenylethanolamine N-Methyltransferase; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1996 |
3,7-Disubstituted-1,2,3,4-tetrahydroisoquinolines display remarkable potency and selectivity as inhibitors of phenylethanolamine N-methyltransferase versus the alpha2-adrenoceptor.
Topics: Adrenal Glands; Animals; Binding, Competitive; Cattle; Cerebral Cortex; Enzyme Inhibitors; In Vitro Techniques; Isoquinolines; Ligands; Male; Models, Molecular; Phenylethanolamine N-Methyltransferase; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Tetrahydroisoquinolines | 1999 |
Synthesis and evaluation of 3-trifluoromethyl-7-substituted-1,2,3, 4-tetrahydroisoquinolines as selective inhibitors of phenylethanolamine N-methyltransferase versus the alpha(2)-adrenoceptor.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cattle; Cerebral Cortex; Clonidine; Enzyme Inhibitors; In Vitro Techniques; Isoquinolines; Male; Phenylethanolamine N-Methyltransferase; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Tetrahydroisoquinolines | 1999 |
Enantiospecific synthesis of 3-fluoromethyl-, 3-hydroxymethyl-, and 3-chloromethyl-1,2,3,4-tetrahydroisoquinolines as selective inhibitors of phenylethanolamine N-methyltransferase versus the alpha(2)-adrenoceptor.
Topics: Adrenergic alpha-Antagonists; Animals; Cattle; Cerebral Cortex; Enzyme Inhibitors; In Vitro Techniques; Isoquinolines; Male; Models, Molecular; Phenylethanolamine N-Methyltransferase; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Stereoisomerism; Structure-Activity Relationship; Tetrahydroisoquinolines | 1999 |
Synthesis of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines and comparison with their isosteric 1,2,3,4-tetrahydroisoquinolines as inhibitors of phenylethanolamine N-methyltransferase.
Topics: Crystallography, X-Ray; Humans; Models, Molecular; Phenylethanolamine N-Methyltransferase; Protein Binding; Pyridines; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Tetrahydroisoquinolines | 2008 |