Compounds > 1,2,3,4-tetrahydroisoquinoline
Page last updated: 2024-08-17

1,2,3,4-tetrahydroisoquinoline and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1,2,3,4-tetrahydroisoquinoline has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's4 (50.00)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Booth, RG; Caldera, P; Castagnoli, N; Johnson, EA; Lampen, P; Naiman, N; Rollema, H; Trevor, AJ; Youngster, SK1
Ichikawa, Y; Miura, S; Wu, RF1
Mizuno, Y; Suzuki, K; Yoshida, M1
Nagatsu, T1
Hirata, Y; Nagatsu, T1
Altomare, C; Carotti, A; Carrupt, PA; Cellamare, S; Jenner, P; Marsden, CD; McNaught, KS; Testa, B; Thull, U1
Abe, K; Ishiwata, K; Kawamura, K; Koyanagi, Y; Saitoh, T; Sano, T; Senda, M; Taguchi, K; Toda, J1
Abe, K; Abe, M; Horiguchi, Y; Munakata, H; Nojima, H; Saito, T; Taguchi, K1

Reviews

1 review(s) available for 1,2,3,4-tetrahydroisoquinoline and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

ArticleYear
[The search for endogenous or exogenous MPTP-like substances].
    Rinsho shinkeigaku = Clinical neurology, 1989, Volume: 29, Issue:12

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Chemical Phenomena; Chemistry; Haplorhini; Humans; Isoquinolines; Neurotoxins; Tetrahydroisoquinolines

1989

Other Studies

7 other study(ies) available for 1,2,3,4-tetrahydroisoquinoline and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

ArticleYear
In vivo intracerebral microdialysis studies in rats of MPP+ analogues and related charged species.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Brain; Chemical Phenomena; Chemistry; Corpus Striatum; Dialysis; Dopamine; Kinetics; Lactates; Lactic Acid; Male; Molecular Structure; MPTP Poisoning; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1990
Neurotoxins: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, 1,2,3,4-tetrahydroisoquinoline and 1-methyl-6,7-dihydroxy-tetrahydroisoquinoline as substrates for FAD-containing monooxygenase of porcine liver microsomes.
    Biochemical pharmacology, 1992, Nov-17, Volume: 44, Issue:10

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Isoquinolines; Kinetics; Microsomes, Liver; NADP; Neurotoxins; Oxygenases; Swine; Tetrahydroisoquinolines

1992
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-like compounds on mitochondrial respiration.
    Advances in neurology, 1990, Volume: 53

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Triphosphate; Animals; Brain; Dose-Response Relationship, Drug; Energy Metabolism; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Parkinson Disease, Secondary; Quinone Reductases; Tetrahydroisoquinolines; Tetrahydropapaveroline

1990
Inhibition of the tyrosine hydroxylase system by MPTP, 1-methyl-4-phenylpyridinium ion (MPP+) and the structurally related compounds in vitro and in vivo.
    European neurology, 1987, Volume: 26 Suppl 1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Brain; Corpus Striatum; Hypothalamus; Isoquinolines; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Pyridines; Pyridinium Compounds; Rats; Structure-Activity Relationship; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase

1987
Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Biochemical pharmacology, 1995, Nov-27, Volume: 50, Issue:11

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Dopamine Agents; Electron Transport Complex II; Electron Transport Complex III; Isoquinolines; Male; Mitochondria; Multienzyme Complexes; NAD(P)H Dehydrogenase (Quinone); Oxidoreductases; Rats; Rats, Wistar; Structure-Activity Relationship; Succinate Dehydrogenase; Tetrahydroisoquinolines

1995
Evaluation of neurotoxicity of TIQ and MPTP and of parkinsonism-preventing effect of 1-MeTIQ by in vivo measurement of pre-synaptic dopamine transporters and post-synaptic dopamine D(2) receptors in the mouse striatum.
    Journal of neurochemistry, 2001, Volume: 79, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Binding, Competitive; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Hypokinesia; Isoquinolines; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Parkinsonian Disorders; Radioligand Assay; Receptors, Dopamine D2; Stereoisomerism; Substantia Nigra; Synapses; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase; Up-Regulation

2001
Effects of 1-cyclohexyl- and 1-cyclohexyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline on dopaminergic spontaneous discharge in nigral neurons of rats.
    Brain research bulletin, 2016, Volume: 121

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Animals; Dopamine; Dopamine Agents; Drug Interactions; Male; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Substantia Nigra; Tetrahydroisoquinolines; Thiobarbituric Acid Reactive Substances

2016