1,2,3,4-tetrahydroisoquinoline has been researched along with 1-methyl-1,2,3,4-tetrahydroisoquinoline in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (22.22) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grunewald, GL; Monn, JA; Sall, DJ | 1 |
| Matsuura, S; Nagatsu, T; Naoi, M; Takahashi, T | 1 |
| Hirobe, M; Makino, Y; Ohta, S; Tachikawa, O | 1 |
| Hirobe, M; Kohno, M; Ohta, S | 1 |
| Nagatsu, T; Ogawa, M; Suzuki, K; Yoshida, M | 1 |
| Dostert, P; Maruyama, W; Minami, M; Nagatsu, T; Naoi, M; Takahashi, A; Takahashi, T | 1 |
| Ayala, A; Cano, J; Machado, A; Parrado, J | 1 |
| Dostert, P; Nagatsu, T; Naoi, M; Yoshida, M | 1 |
| Fujitani, M; Kotake, Y; Makino, Y; Ohta, S; Shintani, H; Yamakawa, T | 1 |
| Abe, K; Miyatake, T; Ren, J; Sano, T; Shinohara, T; Taguchi, K; Utsunomiya, I; Wasai, T | 1 |
| Abe, K; Ishiwata, K; Kawamura, K; Koyanagi, Y; Saitoh, T; Sano, T; Senda, M; Taguchi, K; Toda, J | 1 |
| Borghi, V; Nalepa, I; Pavone, F; Przewłocka, B; Vetulani, J | 1 |
| Antkiewicz-Michaluk, L; Golembiowska, K; Kajta, M; Lazarewicz, JW; Patsenka, A; Salinska, E; Vetulani, J; Wasik, A; Zieminska, E | 1 |
| Antkiewicz-Michaluk, L; Michaluk, J; Wąsik, A | 1 |
| Antkiewicz-Michaluk, L; Michaluk, J; Możdżeń, E; Romańska, I; Wąsik, A | 2 |
| Antkiewicz-Michaluk, L; Romańska, I; Wąsik, A | 1 |
| Antkiewicz-Michaluk, L; Romańska, I; Wąsik, A; Zelek-Molik, A | 1 |
1 review(s) available for 1,2,3,4-tetrahydroisoquinoline and 1-methyl-1,2,3,4-tetrahydroisoquinoline
| Article | Year |
|---|---|
1-Methyl-1,2,3,4-tetrahydroisoquinoline, an endogenous amine with unexpected mechanism of action: new vistas of therapeutic application.
Topics: Amines; Animals; Brain Chemistry; Cocaine-Related Disorders; Dopamine Antagonists; Humans; Morphine Dependence; Neuroprotective Agents; Rats; Tetrahydroisoquinolines | 2014 |
17 other study(ies) available for 1,2,3,4-tetrahydroisoquinoline and 1-methyl-1,2,3,4-tetrahydroisoquinoline
| Article | Year |
|---|---|
Conformational and steric aspects of the inhibition of phenylethanolamine N-methyltransferase by benzylamines.
Topics: Benzylamines; Binding Sites; Isoquinolines; Molecular Conformation; Phenylethanolamine N-Methyltransferase; Structure-Activity Relationship; Tetrahydroisoquinolines | 1988 |
A N-methyltransferase in human brain catalyses N-methylation of 1,2,3,4-tetrahydroisoquinoline into N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of a dopaminergic neurotoxin, N-methylisoquinolinium ion.
Topics: Cerebral Cortex; Chromatography, High Pressure Liquid; Humans; Isoquinolines; Kinetics; Methyltransferases; Neurotoxins; Subcellular Fractions; Substrate Specificity; Tetrahydroisoquinolines | 1989 |
Presence of tetrahydroisoquinoline and 1-methyl-tetrahydro-isoquinoline in foods: compounds related to Parkinson's disease.
Topics: Animals; Blood-Brain Barrier; Brain; Cacao; Cheese; Chemical Phenomena; Chemistry; Food Analysis; Gas Chromatography-Mass Spectrometry; Isoquinolines; Male; Parkinson Disease; Phenethylamines; Rats; Rats, Inbred Strains; Tetrahydroisoquinolines; Wine | 1988 |
Tetrahydroisoquinoline and 1-methyl-tetrahydroisoquinoline as novel endogenous amines in rat brain.
Topics: Animals; Biogenic Amines; Brain Chemistry; Gas Chromatography-Mass Spectrometry; Isoquinolines; Male; Rats; Rats, Inbred Strains; Tetrahydroisoquinolines | 1986 |
Parkinsonism produced by tetrahydroisoquinoline (TIQ) or the analogues.
Topics: Animals; Biopterins; Caudate Nucleus; Dopamine; Female; Isoquinolines; Levodopa; Male; Neurons; Parkinson Disease, Secondary; Putamen; Saimiri; Structure-Activity Relationship; Substantia Nigra; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase | 1993 |
Cytotoxicity of dopamine-derived 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines.
Topics: Animals; Cell Division; Cell Survival; Dopamine; Isoquinolines; PC12 Cells; Quinolinium Compounds; Rats; Salsoline Alkaloids; Structure-Activity Relationship; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase | 1993 |
Reduction of 1-methyl 1,2,3,4-tetrahydroisoquinoline level in substantia nigra of the aged rat.
Topics: Aging; Analysis of Variance; Animals; Gas Chromatography-Mass Spectrometry; Isoquinolines; Male; Rats; Rats, Wistar; Substantia Nigra; Tetrahydroisoquinolines | 1994 |
N-methylated tetrahydroisoquinolines as dopaminergic neurotoxins.
Topics: Animals; Brain; Cell Death; Culture Techniques; Dopamine; Humans; Isoquinolines; Methylation; Methyltransferases; Monoamine Oxidase; Nerve Degeneration; Parkinson Disease; Rats; Receptors, Dopamine; Substantia Nigra; Tetrahydroisoquinolines | 1993 |
Regional distribution of parkinsonism-preventing endogenous tetrahydroisoquinoline derivatives and an endogenous parkinsonism-preventing substance-synthesizing enzyme in monkey brain.
Topics: Animals; Brain; Isoquinolines; Macaca fascicularis; Parkinsonian Disorders; Tetrahydroisoquinolines; Tissue Distribution | 1999 |
Stereoselective effect of (R)- and (S)-1-methyl-1,2,3,4-tetrahydroisoquinolines on a mouse model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Cell Count; Disease Models, Animal; Dopamine; Dopamine Antagonists; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypokinesia; Immunohistochemistry; Isoquinolines; Levodopa; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Neurotoxins; Parkinsonian Disorders; Serotonin; Stereoisomerism; Substantia Nigra; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase | 2001 |
Evaluation of neurotoxicity of TIQ and MPTP and of parkinsonism-preventing effect of 1-MeTIQ by in vivo measurement of pre-synaptic dopamine transporters and post-synaptic dopamine D(2) receptors in the mouse striatum.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Binding, Competitive; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Hypokinesia; Isoquinolines; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Parkinsonian Disorders; Radioligand Assay; Receptors, Dopamine D2; Stereoisomerism; Substantia Nigra; Synapses; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase; Up-Regulation | 2001 |
The interaction of tetrahydroisoquinoline derivatives with antinociceptive action of morphine and oxotremorine in mice.
Topics: Acetylcholine; Analgesics; Animals; Central Nervous System; Drug Synergism; Male; Mice; Morphine; Nociceptors; Norepinephrine; Opioid Peptides; Oxotremorine; Pain; Pain Measurement; Reaction Time; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Tetrahydroisoquinolines | 2003 |
The mechanism of 1,2,3,4-tetrahydroisoquinolines neuroprotection: the importance of free radicals scavenging properties and inhibition of glutamate-induced excitotoxicity.
Topics: Analysis of Variance; Animals; Animals, Newborn; Calcium Isotopes; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Free Radical Scavengers; Glutamic Acid; Glycine; L-Lactate Dehydrogenase; Male; Mice; Microdialysis; Neocortex; Neurons; Neuroprotective Agents; Protein Binding; Rats; Rats, Wistar; Tetrahydroisoquinolines; Time Factors | 2006 |
Antidepressant-like effect of tetrahydroisoquinoline amines in the animal model of depressive disorder induced by repeated administration of a low dose of reserpine: behavioral and neurochemical studies in the rat.
Topics: Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Dopamine; Hypothalamus; Male; Motor Activity; Neuropsychological Tests; Norepinephrine; Nucleus Accumbens; Rats, Wistar; Reserpine; Serotonin; Tetrahydroisoquinolines | 2014 |
Comparison of the Effects of Acute and Chronic Administration of Tetrahydroisoquinoline Amines on the In Vivo Dopamine Release: A Microdialysis Study in the Rat Striatum.
Topics: Animals; Corpus Striatum; Dopamine; Dopamine Agents; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Parkinsonian Disorders; Rats, Wistar; Tetrahydroisoquinolines; Time Factors | 2016 |
Antidepressant-like effect of 1,2,3,4-tetrahydroisoquinoline and its methyl derivative in animal models of depression.
Topics: Animals; Antidepressive Agents; Brain; Chromatography, High Pressure Liquid; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Hindlimb Suspension; Imipramine; Male; Mice; Mice, Inbred C57BL; Swimming; Tetrahydroisoquinolines | 2017 |
Multiple Administration of Endogenous Amines TIQ and 1MeTIQ Protects Against a 6-OHDA-Induced Essential Fall of Dopamine Release in the Rat Striatum: In Vivo Microdialysis Study.
Topics: Analysis of Variance; Animals; Corpus Striatum; Dopamine; Exploratory Behavior; Functional Laterality; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Oxidopamine; Rats; Rats, Wistar; Sympatholytics; Tetrahydroisoquinolines; Time Factors; Tyrosine 3-Monooxygenase | 2018 |