Compounds > 1-2-3-4-6-pentakis-O-galloyl-beta-D-glucose

1-2-3-4-6-pentakis-O-galloyl-beta-D-glucose and chebulagic-acid

1-2-3-4-6-pentakis-O-galloyl-beta-D-glucose has been researched along with chebulagic-acid* in 1 studies

Other Studies

1 other study(ies) available for 1-2-3-4-6-pentakis-O-galloyl-beta-D-glucose and chebulagic-acid

Article	Year
Inhibition of HIV-1 integrase by galloyl glucoses from Terminalia chebula and flavonol glycoside gallates from Euphorbia pekinensis. Planta medica, 2002, Volume: 68, Issue:5 The bioassay-directed isolation of Terminalia chebula fruits afforded four human immunodeficiency virus type 1 (HIV-1) integrase inhibitors, gallic acid ( 1) and three galloyl glucoses ( 2 - 4). In addition, four flavonol glycoside gallates ( 5 - 8) from Euphorbia pekinensis containing the galloyl moiety also showed the inhibitory activity at a level comparable to those of 2 - 4. By comparison with the activities of the compounds not bearing this moiety, it is proposed that the galloyl moiety plays a major role for inhibition against the 3'-processing of HIV-1 integrase of these compounds. Topics: Benzopyrans; Carbohydrate Sequence; Euphorbia; Flavonoids; Fruit; Gallic Acid; Glucosides; Glycosides; HIV Integrase; HIV Integrase Inhibitors; Hydrolyzable Tannins; Molecular Sequence Data; Molecular Structure; Plant Extracts; RNA-Directed DNA Polymerase; Rutin; Tannins; Terminalia	2002

Article

Year

Inhibition of HIV-1 integrase by galloyl glucoses from Terminalia chebula and flavonol glycoside gallates from Euphorbia pekinensis.

Planta medica, 2002, Volume: 68, Issue:5

The bioassay-directed isolation of Terminalia chebula fruits afforded four human immunodeficiency virus type 1 (HIV-1) integrase inhibitors, gallic acid ( 1) and three galloyl glucoses ( 2 - 4). In addition, four flavonol glycoside gallates ( 5 - 8) from Euphorbia pekinensis containing the galloyl moiety also showed the inhibitory activity at a level comparable to those of 2 - 4. By comparison with the activities of the compounds not bearing this moiety, it is proposed that the galloyl moiety plays a major role for inhibition against the 3'-processing of HIV-1 integrase of these compounds.

Topics: Benzopyrans; Carbohydrate Sequence; Euphorbia; Flavonoids; Fruit; Gallic Acid; Glucosides; Glycosides; HIV Integrase; HIV Integrase Inhibitors; Hydrolyzable Tannins; Molecular Sequence Data; Molecular Structure; Plant Extracts; RNA-Directed DNA Polymerase; Rutin; Tannins; Terminalia

2002