1-1-diphenyl-2-picrylhydrazyl and sodium-bromide

1-1-diphenyl-2-picrylhydrazyl has been researched along with sodium-bromide* in 3 studies

Other Studies

3 other study(ies) available for 1-1-diphenyl-2-picrylhydrazyl and sodium-bromide

ArticleYear
Induced production of 6,9-dibromoflavasperone, a new radical scavenging naphthopyranone in the marine-mudflat-derived fungus Aspergillus niger.
    Archives of pharmacal research, 2016, Volume: 39, Issue:6

    The addition of metal bromides (NaBr and CaBr2) during fermentation of the marine-mudflat-derived fungus Aspergillus niger induced production of a new radical scavenging brominated naphthopyranone, 6,9-dibromoflavasperone (1); and three known naphtho-γ-pyranone monomers, flavasperone (2), TMC-256A1 (3), and fonsecin (4); and one naphtho-γ-pyranone dimer, aurasperone B (5). The structure of 6,9-dibromoflavasperone (1) was assigned through the combination of spectroscopic data analyses and comparison with the spectral data of flavasperone (2). Compounds 1-5 displayed potent radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl, with IC50 values of 21, 25, 0.3, 0.02, and 0.01 μM, respectively, and 3-5 were more potent than the positive control, ascorbic acid (IC50, 20.0 μM).

    Topics: Aspergillus niger; Biphenyl Compounds; Bromides; Calcium Compounds; Chromones; Drug Discovery; Fermentation; Free Radical Scavengers; Free Radicals; Geologic Sediments; Picrates; Sodium Compounds

2016
Antioxidant activities of a polyglucuronic acid sodium salt obtained from TEMPO-mediated oxidation of xanthan.
    Carbohydrate polymers, 2015, Feb-13, Volume: 116

    A xanthouronic acid sodium salt called xanthouronan was produced from xanthan by regioselective oxidation with NaOCl/NaBr using 2,2,6,6-tetramethylpiperidine-1-oxy radical (TEMPO) as catalyst. The efficiency of the one pot TEMPO-mediated oxidation was confirmed by HPAEC-PAD, (13)C NMR, and FT-IR. The oxidation degree was close to 98% and the mass yield of this new polyglucuronic acid was higher than 90% (w/w). The macromolecular characterization of xanthouronan using SEC-MALLS showed a molecular size reduced by a third due to the oxidation treatment and the degree of polymerization (DP) of the xanthouronan form was about 665. The evaluation of the enzymatic degradation of this C-6 carboxylated xanthan by various polysaccharide hydrolases and one polysaccharide lyase showed its high resistant to biodegradation. The antioxidant activity of xanthouronan was also tested by using the 2,2'-diphenyl-1-picrylhydrazyle (DPPH) and hydroxyl radical procedures. At 1 g/L, xanthouronan presented 75% of the ascorbic acid antioxidant activity.

    Topics: Antioxidants; Biphenyl Compounds; Bromides; Catalysis; Cyclic N-Oxides; Oxidation-Reduction; Picrates; Polysaccharides; Polysaccharides, Bacterial; Sodium Compounds; Sodium Hydroxide; Sodium Hypochlorite; Uronic Acids

2015
Biochemical activities of 6-carboxy β-chitin derived from squid pens.
    Carbohydrate polymers, 2013, Jan-02, Volume: 91, Issue:1

    TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl radical)-mediated 6-carboxy β-chitin derivatives (T-chitin) with different carboxylate content were successfully synthesized by controlling the addition level of NaClO as the primary oxidant. The structural and biochemical properties of the derivatives were investigated. The carboxylate contents of the derivatives calculated by electrical conductivity titration were 1.33, 1.68, 1.80, and 2.08 mmol/g, respectively. The yield of T-chitin with carboxylate content of 2.08 mmol/g reached 74.55%. T-chitin exhibited stronger bile acid binding capacities than that of β-chitin. The scavenging ability of T-chitin against hydroxyl radicals improved with increasing concentration, and EC(50) values were below 1.2 mg/mL. All T-chitin exhibited a strong ferrous ion chelating effect. At 8 mg/mL, the chelating effects of T-chitin with carboxylate content of 0.81 mmol/g reached 80.15%. These results showed that T-chitin had good bile acid binding capacity and antioxidant activities and it may be a potential antioxidant in vitro.

    Topics: Animal Shells; Animals; Bile Acids and Salts; Biphenyl Compounds; Bromides; Carboxylic Acids; Chitin; Cyclic N-Oxides; Decapodiformes; Free Radical Scavengers; Hydroxyl Radical; Iron Chelating Agents; Oxidation-Reduction; Picrates; Sodium Compounds; Sodium Hypochlorite

2013