1-1-diphenyl-2-picrylhydrazyl has been researched along with scutellarein* in 3 studies
3 other study(ies) available for 1-1-diphenyl-2-picrylhydrazyl and scutellarein
| Article | Year |
|---|---|
Phytochemical analysis and biological activities of in vitro cultured Nidularium procerum, a bromeliad vulnerable to extinction.
This study reports the first phytochemical and biological characterization in treatment of adrenocortical carcinoma cells (H295R) of extracts from Nidularium procerum, an endemic bromeliad of Atlantic Forest vulnerable to extinction. Extracts of dry leaves obtained from in vitro-grown plants were recovered by different extraction methods, viz., hexanoic, ethanolic, and hot and cold aqueous. Chromatography-based metabolite profiling and chemical reaction methods revealed the presence of flavonoids, steroids, lipids, vitamins, among other antioxidant and antitumor biomolecules. Eicosanoic and tricosanoic acids, α-Tocopherol (vitamin E) and scutellarein were, for the first time, described in the Nidularium group. Ethanolic and aqueous extracts contained the highest phenolic content (107.3 mg of GAE.100 g Topics: Animals; Apigenin; Biphenyl Compounds; Bromeliaceae; Cell Line, Tumor; Fatty Acids, Unsaturated; Humans; Mice; Phytochemicals; Picrates; RAW 264.7 Cells; Vitamin E | 2020 |
Synthesis and Bioactivity Characterization of Scutellarein Sulfonated Derivative.
Scutellarin ( Topics: Animals; Antioxidants; Apigenin; Biphenyl Compounds; Brain Ischemia; Cerebrovascular Disorders; Chromans; Erigeron; Fibrinolytic Agents; Free Radical Scavengers; Glucuronates; Humans; Male; Picrates; Rabbits; Solubility | 2017 |
Synthesis and bio-activity evaluation of scutellarein as a potent agent for the therapy of ischemic cerebrovascular disease.
Scutellarein, the main metabolite of scutellarin in vivo, has relatively better solubility, bioavailability and bio-activity than scutellarin. However, it is very difficult to obtain scutellarein in nature compared with scutellarin. Therefore, the present study focused on establishing an efficient route for the synthesis of scutellarein by hydrolyzing scutellarin. The in vitro antioxidant activities of scutellarein were evaluated by measuring its scavenging capacities toward DPPH, ABTS(+•), (•)OH free radicals and its protective effect on H(2)O(2)-induced cytotoxicity in PC12 cells using MTT assay method. The results showed that essential point to the synthesis was the implementation of H(2)SO(4) in 90% ethanol in N(2) atmosphere; scutellarein had stronger antioxidant activity than scutellarin. The results have laid the foundation for further research and the development of scutellarein as a promising candidate for ischemic cerebrovascular disease. Topics: Animals; Apigenin; Benzothiazoles; Biphenyl Compounds; Cell Survival; Cerebrovascular Disorders; Free Radical Scavengers; Glucuronates; Hydrogen Peroxide; Ischemia; PC12 Cells; Picrates; Rats; Sulfonic Acids | 2011 |