1-1-diphenyl-2-picrylhydrazyl and nickel-monoxide

We investigated a novel inorganic (nickel oxide) nanoparticles as a potential antioxidant in the biosystems. The particles were synthesized using self-propagating high-temperature synthesis (SHS) method at 650 degrees C. The antioxidant property of the nickel oxide particles was investigated in an in vitro system, using modified DPPH method for insoluble solid materials.

Topics: Antioxidants; Biphenyl Compounds; Free Radical Scavengers; Nanoparticles; Nickel; Picrates; Time Factors; X-Ray Diffraction

The present work is a modification for Serpen et al.'s method for antioxidant activity determination for insoluble materials with special reference to metal oxide nanoparticles. As reported in our former publications the mixing procedures were followed as mentioned by Serpen et al. A new mixing procedure was followed for enhancing the reaction between metal oxide nanoparticles and DPPH in the solution. The sonication inside a water bath enhances the DPPH scavenging capacity of metal oxide nanoparticles up to 13.94% and 18.96% in case of ferric oxide and nickel oxide nanoparticles respectively. The control DPPH solution without any nanoparticles does not show any degradation due to sonication.

Topics: Antioxidants; Biphenyl Compounds; Ferric Compounds; Free Radical Scavengers; Metal Nanoparticles; Nickel; Picrates; Sonication; X-Ray Diffraction