Compounds > 1-1-diphenyl-2-picrylhydrazyl

1-1-diphenyl-2-picrylhydrazyl and monascin

1-1-diphenyl-2-picrylhydrazyl has been researched along with monascin* in 2 studies

Other Studies

2 other study(ies) available for 1-1-diphenyl-2-picrylhydrazyl and monascin

Article	Year
Theoretical and experimental investigation of the antioxidative activity of monascin. Food & function, 2020, Jul-22, Volume: 11, Issue:7 Monascin, a specific type of monascus pigments, exhibits many bioactivities. In this study, the antioxidative activity of monascin was investigated by theoretical and experimental methods. First, the antioxidant potential of six monascus pigments was predicted by density functional theory (DFT) and time-dependent density functional theory (TDDFT) at the B3LYP/6-31+G (d, p) level, and monascus yellow pigments were predicted to have strong antioxidant capacity, as they can transfer hydrogen to free radicals and accept electrons from radicals. Then, the free radical-scavenging capacity of monascin for 2,2-diphenyl-1-picrylhydrazyl (DPPH), superoxide, and hydroxyl radicals was experimentally validated by electron spin resonance (ESR) measurement. Monascin exhibited a quenching effect on DPPH, superoxide, and hydroxyl radicals in a dose-dependent manner. Specifically, the scavenging activity of monascin for DPPH, superoxide, and hydroxyl radicals was 97.5%, 59.5%, and 68.6%, respectively, when 0.1 mg mL-1 monascin was present. Our study provides theoretical evidence for the strong antioxidative activity of monascin and offers a simple and reliable strategy to determine the antioxidative activity. Topics: Antioxidants; Biphenyl Compounds; Electron Spin Resonance Spectroscopy; Heterocyclic Compounds, 3-Ring; Humans; Monascus; Phytotherapy; Picrates	2020
Secondary metabolites from the red mould rice of Monascus purpureus BCRC 38113. Natural product research, 2010, Volume: 24, Issue:18 One new tetralone, monaspurpurone (1), was isolated from the EtOH extract of a yellow mutant of the fungus Monascus purpureus BCRC 38113 (Eurotiaceae) grown on rice, along with five known compounds, β-sitosteryl palmitate (2), ergosterol (3), ankaflavin (4), monascin (5) and p-nitrophenol (6). They were characterised on the basis of spectral analysis and comparison with literature data. All the isolates were also evaluated for the scavenging properties towards the DPPH in TLC autographic and spectroscopic assays. Topics: Biphenyl Compounds; Chromatography, Thin Layer; Ergosterol; Flavins; Free Radical Scavengers; Heterocyclic Compounds, 3-Ring; Molecular Structure; Monascus; Nitrophenols; Oryza; Palmitates; Picrates; Sitosterols; Spectrum Analysis; Tetralones	2010

Article

Year

Theoretical and experimental investigation of the antioxidative activity of monascin.

Food & function, 2020, Jul-22, Volume: 11, Issue:7

Monascin, a specific type of monascus pigments, exhibits many bioactivities. In this study, the antioxidative activity of monascin was investigated by theoretical and experimental methods. First, the antioxidant potential of six monascus pigments was predicted by density functional theory (DFT) and time-dependent density functional theory (TDDFT) at the B3LYP/6-31+G (d, p) level, and monascus yellow pigments were predicted to have strong antioxidant capacity, as they can transfer hydrogen to free radicals and accept electrons from radicals. Then, the free radical-scavenging capacity of monascin for 2,2-diphenyl-1-picrylhydrazyl (DPPH), superoxide, and hydroxyl radicals was experimentally validated by electron spin resonance (ESR) measurement. Monascin exhibited a quenching effect on DPPH, superoxide, and hydroxyl radicals in a dose-dependent manner. Specifically, the scavenging activity of monascin for DPPH, superoxide, and hydroxyl radicals was 97.5%, 59.5%, and 68.6%, respectively, when 0.1 mg mL-1 monascin was present. Our study provides theoretical evidence for the strong antioxidative activity of monascin and offers a simple and reliable strategy to determine the antioxidative activity.

Topics: Antioxidants; Biphenyl Compounds; Electron Spin Resonance Spectroscopy; Heterocyclic Compounds, 3-Ring; Humans; Monascus; Phytotherapy; Picrates

2020

Secondary metabolites from the red mould rice of Monascus purpureus BCRC 38113.

Natural product research, 2010, Volume: 24, Issue:18

One new tetralone, monaspurpurone (1), was isolated from the EtOH extract of a yellow mutant of the fungus Monascus purpureus BCRC 38113 (Eurotiaceae) grown on rice, along with five known compounds, β-sitosteryl palmitate (2), ergosterol (3), ankaflavin (4), monascin (5) and p-nitrophenol (6). They were characterised on the basis of spectral analysis and comparison with literature data. All the isolates were also evaluated for the scavenging properties towards the DPPH in TLC autographic and spectroscopic assays.

Topics: Biphenyl Compounds; Chromatography, Thin Layer; Ergosterol; Flavins; Free Radical Scavengers; Heterocyclic Compounds, 3-Ring; Molecular Structure; Monascus; Nitrophenols; Oryza; Palmitates; Picrates; Sitosterols; Spectrum Analysis; Tetralones

2010