Compounds > 1-1-diphenyl-2-picrylhydrazyl

1-1-diphenyl-2-picrylhydrazyl and lauryl-gallate

1-1-diphenyl-2-picrylhydrazyl has been researched along with lauryl-gallate* in 1 studies

Other Studies

1 other study(ies) available for 1-1-diphenyl-2-picrylhydrazyl and lauryl-gallate

Article	Year
Non-antibiotic antibacterial activity of dodecyl gallate. Bioorganic & medicinal chemistry, 2003, Feb-20, Volume: 11, Issue:4 Dodecyl (C(12)) gallate (3,4,5-trihydroxybenzoate) (1) was found to possess antibacterial activity specifically against Gram-positive bacteria, in addition to its potent antioxidant activity. The time-kill curve study indicates that this amphipathic gallate exhibits bactericidal activity against methicillin resistant Staphylococcus aureus (MRSA) strains. Dodecyl (lauryl) gallate inhibited oxygen consumption in whole cells and oxidation of NADH in membrane preparation. The antibacterial activity of this gallate comes in part from its ability to inhibit the membrane respiratory chain. As far as alkyl gallates are concerned, their antimicrobial spectra and potency depend in part on the hydrophobic portion of the molecule. Topics: Anti-Bacterial Agents; Bacteria; Biphenyl Compounds; Cell Membrane; Culture Media; Free Radicals; Gallic Acid; Gram-Positive Bacteria; Methicillin Resistance; Microbial Sensitivity Tests; NADH, NADPH Oxidoreductases; Oxygen Consumption; Picrates; Reactive Oxygen Species; Staphylococcus aureus; Structure-Activity Relationship; Time Factors	2003

Article

Year

Non-antibiotic antibacterial activity of dodecyl gallate.

Bioorganic & medicinal chemistry, 2003, Feb-20, Volume: 11, Issue:4

Dodecyl (C(12)) gallate (3,4,5-trihydroxybenzoate) (1) was found to possess antibacterial activity specifically against Gram-positive bacteria, in addition to its potent antioxidant activity. The time-kill curve study indicates that this amphipathic gallate exhibits bactericidal activity against methicillin resistant Staphylococcus aureus (MRSA) strains. Dodecyl (lauryl) gallate inhibited oxygen consumption in whole cells and oxidation of NADH in membrane preparation. The antibacterial activity of this gallate comes in part from its ability to inhibit the membrane respiratory chain. As far as alkyl gallates are concerned, their antimicrobial spectra and potency depend in part on the hydrophobic portion of the molecule.

Topics: Anti-Bacterial Agents; Bacteria; Biphenyl Compounds; Cell Membrane; Culture Media; Free Radicals; Gallic Acid; Gram-Positive Bacteria; Methicillin Resistance; Microbial Sensitivity Tests; NADH, NADPH Oxidoreductases; Oxygen Consumption; Picrates; Reactive Oxygen Species; Staphylococcus aureus; Structure-Activity Relationship; Time Factors

2003