1-1-diphenyl-2-picrylhydrazyl has been researched along with aniline* in 2 studies
2 other study(ies) available for 1-1-diphenyl-2-picrylhydrazyl and aniline
| Article | Year |
|---|---|
Synthesis of 2-nitro aniline derivative of 3, 4, 5-trihydroxybenzoic acid, its metal complexes, characterization and bioassay.
Present research work discloses new and novel synthesis of metal complexes (Fe, Cu, Zn, Sb and Sn) of 3, 4, 5-trihydroxybenzoic acid derivative containing aniline moiety with substitution at C-7 position of 3, 4, 5-trihydroxybenzoic acid in order to enhance its biological activities by coupling therapeutic values of transition metals as well. In vitro antibacterial and antifungal activities of these compounds has been performed by using agar diffusion method against different bacterial and fungal strains. The free radical scavenging assay was performed by using 2, 2-diphenyl-1-picryl-hydrazyl (DPPH). Cytotoxic action of compounds was assessed by utilizing the standard MTT (3-[4, 5-dimethylthiazole-2-yl]-2, 5-diphenyl-tetrazolium bromide) colorimetric assay. The structure of newly synthesized complexes were confirmed by using IR and Topics: Aniline Compounds; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Biological Assay; Biphenyl Compounds; Cell Line, Tumor; Coordination Complexes; Fungi; HeLa Cells; Humans; Metals; Picrates | 2020 |
Synthesis, characterization and antioxidant activity of a novel electroactive and biodegradable polyurethane for cardiac tissue engineering application.
There has been a growing trend towards applying conducting polymers for electrically excitable cells to increase electrical signal propagation within the cell-loaded substrates. A novel biodegradable electroactive polyurethane containing aniline pentamer (AP-PU) was synthesized and fully characterized by spectroscopic methods. To tune the physico-chemical properties and biocompatibility, the AP-PU was blended with polycaprolactone (PCL). The presence of electroactive moieties and the electroactivity behavior of the prepared films were confirmed by UV-visible spectroscopy and cyclic voltammetry. A conventional four probe analysis demonstrated the electrical conductivity of the films in the semiconductor range (~10(-5)S/cm). MTT assays using L929 mouse fibroblast and human umbilical vein endothelial cells (HUVECs) showed that the prepared blend (PB) displayed more cytocompatibility compared with AP-PU due to the introduction of a biocompatible PCL moiety. The in vitro cell culture also confirmed that PB was as supportive as tissue culture plate. The antioxidant activity of the AP-PU was proved using 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging assay by employing UV-vis spectroscopy. In vitro degradation tests conducted in phosphate-buffered saline, pH7.4 and pH5.5, proved that the films were also biodegradable. The results of this study have highlighted the potential application of this bioelectroactive polyurethane as a platform substrate to study the effect of electrical signals on cell activities and to direct desirable cell function for tissue engineering applications. Topics: Aniline Compounds; Animals; Antioxidants; Biocompatible Materials; Biphenyl Compounds; Cell Line; Cell Proliferation; Cells, Immobilized; Electric Conductivity; Human Umbilical Vein Endothelial Cells; Humans; Mice; Microscopy, Electron, Scanning; Myocytes, Cardiac; Picrates; Polyesters; Polyurethanes; Tissue Engineering; Tissue Scaffolds | 2014 |