1-1-diphenyl-2-picrylhydrazyl and acacetin

1-1-diphenyl-2-picrylhydrazyl has been researched along with acacetin* in 2 studies

Other Studies

2 other study(ies) available for 1-1-diphenyl-2-picrylhydrazyl and acacetin

ArticleYear
Monoterpene glycosides, phenylpropanoids, and acacetin glycosides from Dracocephalum foetidum.
    Phytochemistry, 2014, Volume: 101

    Chemical investigation of the acetone extract from the aerial parts of the Mongolian medicinal plant Dracocephalum foetidum resulted in the isolation of three limonene glycosides, a caffeic acid trimer, four rosmarinic acid glucosides, and five acacetin acyl glycosides, together with 13 known natural products. The chemical structures of all of the compounds were determined by spectroscopic analyses. Among these compounds three showed hyaluronidase inhibitory activity. In addition, one other compound showed stronger 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity than the positive control Trolox, whereas three other compounds demonstrated a similar activity to that of Trolox.

    Topics: Antioxidants; Biphenyl Compounds; Flavones; Glycosides; Hyaluronoglucosaminidase; Lamiaceae; Medicine, Mongolian Traditional; Mongolia; Monoterpenes; Picrates; Plant Components, Aerial; Plant Extracts; Plants, Medicinal; Propanols

2014
Anti-bacterial and anti-oxidant activities of leaf extracts of Combretum vendae (Combretecacea) and the isolation of an anti-bacterial compound.
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2014, Volume: 11, Issue:5

    Combretum vendae A.E. van Wyk (Combretaceae) is used for the treatment of bacterial related infections and oxidative related diseases by indigenous people of South Africa. Dried leaves extracts of C. vendae were investigated for bioactivity against a variety of bacterial strains and their antioxidant potential evaluated.. Constituents of leaf material were serially extracted using solvents of varying polarities, TLC chromatograms of the fractions were sprayed with 2,2 diphenyl-1-picrylhydrazyl (DPPH) to determine the presence of antioxidant compounds. Bio-autography was used to determine the number of antibacterial compounds active against Staphylococcus aureus, Enterococcus faecalis, Eschericha coli and Pseudomonas aeruginosa. Minimum inhibitory concentration (MIC) values were determined using serial microplate dilution method. The chloroform fraction was subjected to bio-assay guided column chromatography to isolate the active compound.. The mass extracted by different solvents was below 10% dry weight. MIC values for different extracts against different pathogens ranges from 0.08 to 0.64 mg/ml. The compound isolated was identified as acacetin having an Rf value of 0.28 following elution in the Ethanol: Methanol: Water [E: M: W (10: 1.35: 1 v/v). Acacetin had MIC values ranging from 0.16 to 0.35 mg/ml.. We report for the first time the isolation of acacetin as the main antibacterial compound from the leaves of Combretum vendae.

    Topics: Anti-Bacterial Agents; Antioxidants; Bacteria; Biphenyl Compounds; Combretum; Enterococcus faecalis; Flavones; Medicine, African Traditional; Microbial Sensitivity Tests; Picrates; Plant Extracts; Plant Leaves; Pseudomonas aeruginosa; South Africa; Staphylococcus aureus

2014