1-1-diphenyl-2-picrylhydrazyl and 3-acetylcoumarin

1-1-diphenyl-2-picrylhydrazyl has been researched along with 3-acetylcoumarin* in 1 studies

Other Studies

1 other study(ies) available for 1-1-diphenyl-2-picrylhydrazyl and 3-acetylcoumarin

ArticleYear
A new and efficient method for the synthesis of novel 3-acetyl coumarins oxadiazoles derivatives with expected biological activity.
    Molecules (Basel, Switzerland), 2014, Jan-14, Volume: 19, Issue:1

    This paper presents the design of some novel 3-acetylcoumarin derivatives, based on minimal inhibitory concentration values (MICs) previously obtained against some microorganism cultures, Gram positive and negative bacteria and fungi. Some of these molecules exhibited antibacterial activity against S. aureus, comparable to that of the standard used (impinem). The in vitro antioxidant activities of the novel 3-acetylcoumarin oxadiazoles were assayed by the quantitative 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity method. The compounds 5c,d proved to be the most active, showing the highest capacity to deplete the DPPH radicals. Structure elucidation of the products has been accomplished on the basis of IR, 1H-NMR, 13C-NMR, NOESY and HMBC NMR data.

    Topics: Anti-Bacterial Agents; Antifungal Agents; Bacillus subtilis; Benzothiazoles; Biphenyl Compounds; Coumarins; Escherichia coli; Fluconazole; Free Radical Scavengers; Free Radicals; Fungi; Microbial Sensitivity Tests; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Oxadiazoles; Picrates; Salmonella typhi; Shigella flexneri; Staphylococcus aureus; Sulfonic Acids

2014