Compounds > 1-1-diphenyl-2-picrylhydrazyl

1-1-diphenyl-2-picrylhydrazyl and 1-5-anhydrofructose

1-1-diphenyl-2-picrylhydrazyl has been researched along with 1-5-anhydrofructose* in 1 studies

Other Studies

1 other study(ies) available for 1-1-diphenyl-2-picrylhydrazyl and 1-5-anhydrofructose

Article	Year
Antioxidant effects of 1,5-anhydro-D-fructose, a new natural sugar, in vitro. Planta medica, 2002, Volume: 68, Issue:1 The antioxidant effects of 1,5-anhydro-D-fructose (1,5-AF), a unique anhydrohexulose, were studied in 1,1-diphenyl-2-picrylhydrazyl (DPPH) solution, in human cells along with lipid peroxidation of low-density lipoprotein (LDL). We have confirmed that 1,5-AF scavenges DPPH radicals directly in solution and inhibits the formation of hydrogen peroxide and superoxide anion, typical reactive oxygen species (ROS), induced by phorbol myristate acetate (PMA) in a dose-dependent manner in THP-1 cells. We also observed the dose-dependent antioxidant effects of 1,5-AF on copper-mediated LDL oxidation. These findings suggest that 1,5-AF might play a role in reducing the risk of atherosclerosis and may help prevent coronary heart disease. Topics: Antioxidants; Bepridil; Biological Factors; Biphenyl Compounds; Carbohydrates; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Free Radicals; Fructose; Humans; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Molecular Structure; Monocytes; Picrates; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate	2002

Article

Year

Antioxidant effects of 1,5-anhydro-D-fructose, a new natural sugar, in vitro.

Planta medica, 2002, Volume: 68, Issue:1

The antioxidant effects of 1,5-anhydro-D-fructose (1,5-AF), a unique anhydrohexulose, were studied in 1,1-diphenyl-2-picrylhydrazyl (DPPH) solution, in human cells along with lipid peroxidation of low-density lipoprotein (LDL). We have confirmed that 1,5-AF scavenges DPPH radicals directly in solution and inhibits the formation of hydrogen peroxide and superoxide anion, typical reactive oxygen species (ROS), induced by phorbol myristate acetate (PMA) in a dose-dependent manner in THP-1 cells. We also observed the dose-dependent antioxidant effects of 1,5-AF on copper-mediated LDL oxidation. These findings suggest that 1,5-AF might play a role in reducing the risk of atherosclerosis and may help prevent coronary heart disease.

Topics: Antioxidants; Bepridil; Biological Factors; Biphenyl Compounds; Carbohydrates; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Free Radicals; Fructose; Humans; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Molecular Structure; Monocytes; Picrates; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate

2002