1,1-dimethylheptyl-11-hydroxytetrahydrocannabinol has been researched along with cyclohexanol in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (26.83) | 18.2507 |
| 2000's | 21 (51.22) | 29.6817 |
| 2010's | 9 (21.95) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abood, ME; Kaminski, NE; Kessler, FK; Martin, BR; Schatz, AR | 1 |
| Champion, TM; Howlett, AC; Mechoulam, R; Wilken, GH | 1 |
| Kaminski, NE | 1 |
| Burkey, TH; Consroe, P; Ehlert, FJ; Hosohata, Y; Quock, RM; Roeske, WR; Yamamura, HI | 1 |
| Hiley, CR; White, R | 1 |
| Bonhaus, DW; Chang, LK; Kwan, J; Martin, GR | 1 |
| Baba, N; Ishima, Y; Kodaka, T; Kondo, S; Miyashita, T; Nakane, S; Seki, C; Sugiura, T; Suhara, Y; Takayama, H; Waku, K | 1 |
| Cadogan, AK; Cheer, JF; Fone, KC; Kendall, DA; Marsden, CA | 1 |
| Bonner, TI; Herkenham, M; Hohmann, AG; Zimmer, A; Zimmer, AM | 1 |
| Brown, S; Derleth, C; Hsieh, C; Mackie, K | 1 |
| Göthert, M; Likungu, J; Molderings, GJ | 1 |
| Fox, A; Gentry, C; James, I; Kesingland, A; McNair, K; Patel, S; Urban, L | 1 |
| Guaza, C; Molina-Holgado, E; Molina-Holgado, F; Rothwell, NJ | 1 |
| Christopoulos, A; Devlin, MG | 1 |
| Breivogel, CS; Crim, JL; Darmani, NA; Janoyan, JJ; Martin, BR; Parekh, B; Sim-Selley, LJ | 1 |
| Carai, MA; Casu, MA; Gessa, GL; Marchese, G; Pani, L; Porcella, A; Reali, R; Ruiu, S; Saba, P | 1 |
| Del Giudice, E; Facchinetti, F; Furegato, S; Leon, A; Passarotto, M | 1 |
| Rhee, MH | 1 |
| De Vry, J; Eckel, G; Jentzsch, KR; Kuhl, E | 1 |
| Battista, N; Bernardi, G; Calabresi, P; Centonze, D; Finazzi-Agrò, A; Maccarrone, M; Mercuri, NB; Rossi, S | 1 |
| De Vry, J; Jentzsch, KR | 1 |
| Hille, B; Lauckner, JE; Mackie, K | 1 |
| Carchenilla, MS; Jacobsson, SO; Johansson, M; Persson, E; Svensson, AC | 1 |
| Fowler, CJ; Jacobsson, SO; Nilsson, O | 1 |
| Marron Fernandez de Velasco, E; Rodriguez, RE; Rodriguez-Martin, I | 1 |
| Bosier, B; Hermans, E; Lambert, DM; Najimi, M; Tilleux, S | 1 |
| Abood, ME; Anavi-Goffer, S; Barnett-Norris, J; Fleischer, D; Howlett, AC; Hurst, DP; Lewis, DL; Lynch, DL; Mukhopadhyay, S; Reggio, PH; Shi, S | 1 |
| Deno, G; Fan, X; Gonsiorek, W; Hipkin, RW; Kozlowski, J; Lunn, CA | 1 |
| Bosier, B; Hermans, E; Lambert, D | 1 |
| Bosier, B; Hermans, E; Lambert, DM | 2 |
| Dalton, VS; Wang, H; Zavitsanou, K | 1 |
| Bosier, B; Hermans, E; Lambert, DM; Michotte, Y; Sarre, S; Smolders, I | 1 |
| Dalton, VS; Zavitsanou, K | 1 |
| Bertalovitz, AC; Kendall, DA; Shim, JY | 1 |
| Bosier, B; Hermans, E; Lambert, DM; Mertens, B; Michotte, Y; Muccioli, GG; Sarre, S | 1 |
| Kumar, P; Song, ZH | 1 |
| Hruba, L; McMahon, LR | 1 |
| Christopoulos, A; Glass, M; Khajehali, E; Leach, K; Malone, DT; Sexton, PM | 1 |
| Bonsi, P; Fezza, F; Maccarrone, M; Madeo, G; Maltese, M; Martella, G; Mastrangelo, N; Pisani, A; Rapino, C; Schirinzi, T | 1 |
| Eldeeb, K; Howlett, AC; Leone-Kabler, S | 1 |
41 other study(ies) available for 1,1-dimethylheptyl-11-hydroxytetrahydrocannabinol and cyclohexanol
| Article | Year |
|---|---|
Identification of a functionally relevant cannabinoid receptor on mouse spleen cells that is involved in cannabinoid-mediated immune modulation.
Topics: Animals; Cannabinoids; Cells, Cultured; Cyclohexanols; Dronabinol; Electrophoresis, Agar Gel; Female; Immunosuppressive Agents; Mice; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Cannabinoid; Receptors, Drug; RNA; Spleen; Stereoisomerism | 1992 |
Stereochemical effects of 11-OH-delta 8-tetrahydrocannabinol-dimethylheptyl to inhibit adenylate cyclase and bind to the cannabinoid receptor.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cells, Cultured; Cyclic AMP; Cyclohexanols; Dronabinol; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Cannabinoid; Receptors, Drug | 1990 |
Evidence for a cannabinoid receptor in immunomodulation by cannabinoid compounds.
Topics: Adenylyl Cyclases; Animals; Cannabinoids; Cells, Cultured; Colforsin; Cyclohexanols; Dronabinol; Female; Immunity; Immunoglobulin M; Mice; Receptors, Cannabinoid; Receptors, Drug; Spleen; Stereoisomerism | 1993 |
Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain.
Topics: Animals; Arachidonic Acids; Brain; Cannabinoids; Cells, Cultured; Cyclohexanols; Dronabinol; Endocannabinoids; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Mice, Inbred ICR; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 1997 |
The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery.
Topics: Amides; Animals; Arachidonic Acids; Benzoxazines; Cannabinoids; Cyclohexanols; Dronabinol; Endocannabinoids; Endothelium, Vascular; Ethanolamines; In Vitro Techniques; Ligands; Male; Mesenteric Arteries; Methoxamine; Morpholines; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Palmitic Acids; Polyunsaturated Alkamides; Rats; Rats, Wistar | 1998 |
Dual activation and inhibition of adenylyl cyclase by cannabinoid receptor agonists: evidence for agonist-specific trafficking of intracellular responses.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arachidonic Acids; Benzoxazines; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclohexanols; Dronabinol; Endocannabinoids; Enzyme Activation; Humans; Morpholines; Naphthalenes; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug; Signal Transduction; Transfection | 1998 |
Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds.
Topics: Animals; Arachidonic Acids; Benzoxazines; Cannabinoids; Cell Line; Cyclohexanols; Dronabinol; Endocannabinoids; Models, Chemical; Morpholines; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Structure-Activity Relationship | 1999 |
Modification of 5-HT2 receptor mediated behaviour in the rat by oleamide and the role of cannabinoid receptors.
Topics: Amphetamines; Animals; Behavior, Animal; Cannabinoids; Cerebral Cortex; Cyclohexanols; Dronabinol; Excitatory Amino Acid Antagonists; Hypnotics and Sedatives; Male; Motor Activity; Muscle Contraction; Oleic Acids; Phosphatidylinositols; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Cannabinoid; Receptors, Drug; Receptors, Serotonin; Reflex; Serotonin; Serotonin Receptor Agonists | 1999 |
Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice.
Topics: Animals; Behavior, Animal; Body Temperature; Brain; Central Nervous System; Cyclohexanols; Dronabinol; Gene Targeting; Mice; Mice, Knockout; Molecular Structure; Motor Activity; Receptors, Cannabinoid; Receptors, Drug | 1999 |
Internalization and recycling of the CB1 cannabinoid receptor.
Topics: Acids; Ammonium Chloride; Animals; Arachidonic Acids; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Cells, Cultured; Clathrin; Coated Vesicles; Cyclohexanols; Dronabinol; Drug Tolerance; Endocytosis; Endosomes; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Immunosuppressive Agents; Morpholines; Mutagenesis; Naphthalenes; Phosphorylation; Piperidines; Protein Binding; Protein Structure, Tertiary; Pyrazoles; Rats; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Transfection; Up-Regulation; Virulence Factors, Bordetella | 1999 |
Presynaptic cannabinoid and imidazoline receptors in the human heart and their potential relationship.
Topics: Adrenergic Uptake Inhibitors; Arachidonic Acids; Atrial Function; Corticosterone; Cyclohexanols; Desipramine; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Electrophysiology; Endocannabinoids; Excitatory Amino Acid Agonists; Female; Guanidine; Humans; Imidazoles; Imidazoline Receptors; Ligands; Male; Norepinephrine; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug; Receptors, Presynaptic; Sympathetic Nervous System; Sympathomimetics | 1999 |
The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain.
Topics: Analgesics; Animals; Benzoxazines; Cannabinoids; Cyclohexanols; Disease Models, Animal; Dronabinol; Hyperalgesia; Morpholines; Naphthalenes; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Sciatica | 2001 |
Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide-induced nitric oxide release in astrocyte cultures.
Topics: Analgesics; Animals; Arachidonic Acids; Astrocytes; Calcium Channel Blockers; Camphanes; Cannabinoids; Cells, Cultured; Cyclohexanols; Dronabinol; Endocannabinoids; Gene Expression; Lipopolysaccharides; Mice; Mice, Inbred Strains; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2002 |
Modulation of cannabinoid agonist binding by 5-HT in the rat cerebellum.
Topics: Animals; Benzoxazines; Binding, Competitive; Cannabinoids; Cell Membrane; Cerebellum; Cyclohexanols; Dronabinol; GTP-Binding Proteins; Male; Morpholines; Naphthalenes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, Cannabinoid; Receptors, Drug; Receptors, Serotonin; Serotonin | 2002 |
Antiemetic and motor-depressive actions of CP55,940: cannabinoid CB1 receptor characterization, distribution, and G-protein activation.
Topics: Animals; Antiemetics; Benzoxazines; Binding, Competitive; Brain; Cisplatin; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Injections, Intraperitoneal; Injections, Subcutaneous; Male; Morpholines; Motor Activity; Naphthalenes; Piperidines; Pyrazoles; Radioligand Assay; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Shrews; Sulfur Radioisotopes; Tritium; Vomiting | 2003 |
Differential distribution of functional cannabinoid CB1 receptors in the mouse gastroenteric tract.
Topics: Animals; Antiemetics; Binding, Competitive; Blotting, Western; Cyclohexanols; Digestive System; Dose-Response Relationship, Drug; Dronabinol; Gastric Mucosa; Gastrointestinal Transit; Immunohistochemistry; Intestine, Large; Intestine, Small; Male; Mice; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Stomach; Tritium | 2003 |
Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Arachidonic Acids; Benzoxazines; Brain; Cannabinoids; Cells, Cultured; Cyclohexanols; Dronabinol; Encephalitis; Endocannabinoids; Glycerides; Inflammation Mediators; Microglia; Morpholines; Naphthalenes; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; RNA, Messenger; Tumor Necrosis Factor-alpha | 2003 |
Functional role of serine residues of transmembrane dopamin VII in signal transduction of CB2 cannabinoid receptor.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Blotting, Western; Cannabinoids; Chlorocebus aethiops; COS Cells; Cyclohexanols; Dronabinol; Excitatory Amino Acid Antagonists; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Tertiary; Receptors, Cannabinoid; Receptors, Drug; Serine; Signal Transduction; Transfection | 2002 |
Behavioral effects of cannabinoids show differential sensitivity to cannabinoid receptor blockade and tolerance development.
Topics: Analgesics; Animals; Benzoxazines; Body Temperature; Cannabinoids; Conditioning, Operant; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Drug Tolerance; Excitatory Amino Acid Antagonists; Male; Morpholines; Naphthalenes; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Receptor, Cannabinoid, CB1 | 2004 |
A critical interaction between dopamine D2 receptors and endocannabinoids mediates the effects of cocaine on striatal gabaergic Transmission.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amidohydrolases; Animals; Arachidonic Acids; Cerebral Cortex; Cocaine; Cyclohexanols; Dopamine Agonists; Dose-Response Relationship, Drug; Dronabinol; Electrophysiology; Endocannabinoids; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neostriatum; Patch-Clamp Techniques; Polyunsaturated Alkamides; Quinpirole; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Dopamine D2; Synaptic Transmission; Synaptosomes | 2004 |
Discriminative stimulus effects of the structurally novel cannabinoid CB1/CB2 receptor partial agonist BAY 59-3074 in the rat.
Topics: Alkanesulfonates; Amines; Amitriptyline; Animals; Baclofen; Behavior, Animal; Benzoxazines; Carbamazepine; Cyclohexanecarboxylic Acids; Cyclohexanols; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Gabapentin; gamma-Aminobutyric Acid; Indans; Male; Molecular Structure; Morphine; Morpholines; Naphthalenes; Nitriles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sulfonic Acids | 2004 |
The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins.
Topics: Analgesics; Animals; Arachidonic Acids; Benzoxazines; Calcium; Cannabinoids; Cell Line; Cyclohexanols; Cytoplasm; DNA, Complementary; Dronabinol; Endocannabinoids; Endoplasmic Reticulum; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Glycerides; GTP-Binding Protein alpha Subunits, Gq-G11; Hippocampus; Humans; Immunosuppressive Agents; Morpholines; Naphthalenes; Neurons; Pertussis Toxin; Piperidines; Protein Binding; Protein Conformation; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Rimonabant; Ryanodine; Time Factors; Type C Phospholipases | 2005 |
Expression of functional CB1 cannabinoid receptors in retinoic acid-differentiated P19 embryonal carcinoma cells.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Benzoxazines; Blotting, Western; Calcium; Carcinoma; Cell Differentiation; Cell Line, Tumor; Cyclic AMP; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; gamma-Aminobutyric Acid; Gene Expression; Mice; Morpholines; Naphthalenes; Receptor, Cannabinoid, CB1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Temperature; Tretinoin; Tritium | 2006 |
The cannabinoid agonist WIN 55,212-2 inhibits TNF-alpha-induced neutrophil transmigration across ECV304 cells.
Topics: Analysis of Variance; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cell Line; Cell Movement; Chemotaxis; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Endothelial Cells; Flow Cytometry; Humans; Indoles; Interleukin-8; L-Lactate Dehydrogenase; Morpholines; Naphthalenes; Neutrophils; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Thapsigargin; Tumor Necrosis Factor-alpha | 2006 |
Characterization of cannabinoid-binding sites in zebrafish brain.
Topics: Animals; Benzoxazines; Binding, Competitive; Brain; Cannabinoids; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Excitatory Amino Acid Antagonists; Guanosine 5'-O-(3-Thiotriphosphate); Morpholines; Naphthalenes; Protein Binding; Radioligand Assay; Tritium; Zebrafish | 2007 |
Agonist selective modulation of tyrosine hydroxylase expression by cannabinoid ligands in a murine neuroblastoma cell line.
Topics: Animals; Cannabinoid Receptor Modulators; Cannabinoids; Catecholamines; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cyclohexanols; Dronabinol; Gene Expression Regulation, Enzymologic; Ligands; Mice; Models, Biological; Neuroblastoma; Neurons; Neuroprotective Agents; Promoter Regions, Genetic; Protein Transport; Receptor, Cannabinoid, CB1; Signal Transduction; Tyrosine 3-Monooxygenase | 2007 |
Helix 8 Leu in the CB1 cannabinoid receptor contributes to selective signal transduction mechanisms.
Topics: Amino Acid Sequence; Analgesics; Benzoxazines; Cyclohexanols; Dronabinol; Humans; Leucine; Lipid Bilayers; Molecular Sequence Data; Morpholines; Mutagenesis; Naphthalenes; Pertussis Toxin; Protein Structure, Secondary; Protein Structure, Tertiary; Receptor, Cannabinoid, CB1; Signal Transduction | 2007 |
Sch35966 is a potent, selective agonist at the peripheral cannabinoid receptor (CB2) in rodents and primates.
Topics: Animals; Binding, Competitive; Cell Membrane; Chemotaxis; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Cyclohexanols; Dronabinol; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Indoles; Macaca fascicularis; Mice; Quinolizines; Rats; Receptor, Cannabinoid, CB2; Species Specificity | 2007 |
Differential modulation of AP-1- and CRE-driven transcription by cannabinoid agonists emphasizes functional selectivity at the CB1 receptor.
Topics: Animals; Cell Line, Tumor; Cyclic AMP; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Enhancer Elements, Genetic; Genes, Reporter; GTP-Binding Protein alpha Subunits, Gi-Go; Luciferases, Renilla; Mice; Protein Kinase Inhibitors; Receptor, Cannabinoid, CB1; Signal Transduction; Transcription Factor AP-1; Transcription, Genetic; Transfection | 2008 |
Reciprocal influences of CB1 cannabinoid receptor agonists on ERK and JNK signalling in N1E-115 cells.
Topics: Animals; Cell Line, Tumor; Cyclohexanols; Dronabinol; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Receptor, Cannabinoid, CB1; Signal Transduction | 2008 |
Concomitant activation of adenylyl cyclase suppresses the opposite influences of CB(1) cannabinoid receptor agonists on tyrosine hydroxylase expression.
Topics: Adenylyl Cyclases; Animals; Cannabinoid Receptor Modulators; Cannabinoids; Cell Line, Tumor; Colforsin; Cyclohexanols; DNA Primers; Dronabinol; Enzyme Activation; Excitatory Amino Acid Antagonists; Genes, Reporter; Luciferases; Mice; Neuroblastoma; Pertussis Toxin; Polymerase Chain Reaction; Receptor, Cannabinoid, CB1; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tyrosine 3-Monooxygenase | 2009 |
HU210-induced downregulation in cannabinoid CB1 receptor binding strongly correlates with body weight loss in the adult rat.
Topics: Animals; Autoradiography; Basal Ganglia; Brain; Cerebral Cortex; Cyclohexanols; Down-Regulation; Dronabinol; Male; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Weight Loss | 2009 |
Revisiting the complex influences of cannabinoids on motor functions unravels pharmacodynamic differences between cannabinoid agonists.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cannabinoids; Catalepsy; Cyclohexanols; Dronabinol; Male; Motor Activity; Rats; Rats, Wistar; Time Factors | 2010 |
Cannabinoid effects on CB1 receptor density in the adolescent brain: an autoradiographic study using the synthetic cannabinoid HU210.
Topics: Age Factors; Analgesics; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Brain; Brain Mapping; Cannabinoids; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Male; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Tissue Distribution; Tritium | 2010 |
Identification of essential cannabinoid-binding domains: structural insights into early dynamic events in receptor activation.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Cannabinoids; Cyclohexanols; Dronabinol; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Molecular Dynamics Simulation; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Receptor, Cannabinoid, CB1; Structure-Activity Relationship | 2011 |
Differential modulations of striatal tyrosine hydroxylase and dopamine metabolism by cannabinoid agonists as evidence for functional selectivity in vivo.
Topics: Animals; Cannabinoids; Corpus Striatum; Cyclohexanols; Dopamine; Dose-Response Relationship, Drug; Dronabinol; Male; Protein Binding; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Tyrosine 3-Monooxygenase | 2012 |
Identification of raloxifene as a novel CB2 inverse agonist.
Topics: Benzoxazines; Binding, Competitive; Bone Density Conservation Agents; Colforsin; Cyclic AMP; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Drug Approval; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Morpholines; Naphthalenes; Raloxifene Hydrochloride; Receptor, Cannabinoid, CB2; Transfection; Tritium; United States; United States Food and Drug Administration | 2013 |
The cannabinoid agonist HU-210: pseudo-irreversible discriminative stimulus effects in rhesus monkeys.
Topics: Animals; Behavior, Animal; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cyclohexanols; Discrimination, Psychological; Dose-Response Relationship, Drug; Dronabinol; Female; Macaca mulatta; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Time Factors | 2014 |
Biased Agonism and Biased Allosteric Modulation at the CB1 Cannabinoid Receptor.
Topics: Allosteric Regulation; Animals; Benzoxazines; Cannabinoid Receptor Agonists; CHO Cells; Cricetulus; Cyclohexanols; Dronabinol; Humans; Indoles; MAP Kinase Signaling System; Morpholines; Naphthalenes; Phosphorylation; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Signal Transduction | 2015 |
Dopamine-dependent CB1 receptor dysfunction at corticostriatal synapses in homozygous PINK1 knockout mice.
Topics: Animals; Benzoxazines; Calcium Channel Blockers; Cerebral Cortex; Corpus Striatum; Cyclohexanols; Dopamine; Dopamine Agents; Dronabinol; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Mice; Mice, Transgenic; Morpholines; Naphthalenes; Protein Binding; Protein Kinases; Receptor, Cannabinoid, CB1; Synapses; Time Factors; Tritium | 2016 |
CB1 cannabinoid receptor-mediated increases in cyclic AMP accumulation are correlated with reduced Gi/o function.
Topics: Animals; Cannabinoids; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Cyclohexanols; Dronabinol; GTP-Binding Proteins; Humans; Receptor, Cannabinoid, CB1; Receptors, Dopamine D2; Signal Transduction | 2016 |