1,1,1-trifluoro-2-chloroethane has been researched along with halothane in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (60.00) | 18.7374 |
| 1990's | 8 (32.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blake, JF; Curatolo, WJ; Lombardo, F | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Baker, RK; Brown, BR; Sipes, IG | 1 |
| Cousins, MJ; Jenner, MA; Plummer, JL | 1 |
| Berman, LM; Harbison, RD; James, RC; Roberts, SM; Smith, AC | 1 |
| Cousins, MJ; Plummer, JL; Steven, IM | 1 |
| Kawata, S; Sugiyama, T; Tamura, S; Tarui, S | 1 |
| Fujii, K; Kikuchi, H; Okida, M | 1 |
| Cousins, MJ; Ilsley, AH; McLean, CF; Nancarrow, C; Plummer, JL | 1 |
| Bösterling, B; Trevor, A; Trudell, JR | 1 |
| Baker, MT; Van Dyke, RA | 1 |
| Trevor, A; Trudell, JR | 1 |
| Asmus, KD; Krischer, K; Mönig, J | 1 |
| Ahr, HJ; King, LJ; Nastainczyk, W; Ullrich, V | 1 |
| Brown, BR; Gandolfi, AJ; Lind, RC; Maiorino, RM; Sipes, IG | 1 |
| Adams, JF; Cousins, MJ; Gourlay, GK; Hall, P | 1 |
| Adams, JF; Cousins, MJ; Gourlay, GK; Sharp, JH | 1 |
| Collins, MA; Ellis, MK; Green, T; Naylor, JL | 1 |
| Anders, MW; Jones, JP; Yin, H | 1 |
| Baker, MT; Olson, MJ; Wang, Y | 1 |
| Fujii, K | 1 |
| Kharasch, ED; Spracklin, DK; Thummel, KE | 1 |
| Bortolato, S; Ferrara, R; Manno, M; White, IN; Zanovello, A | 1 |
1 trial(s) available for 1,1,1-trifluoro-2-chloroethane and halothane
| Article | Year |
|---|---|
Effects of combined extradural blockade and general anaesthesia on indocyanine green clearance and halothane metabolism.
Topics: Adult; Aged; Anesthesia, Epidural; Anesthesia, General; Blood Pressure; Female; Halothane; Humans; Indocyanine Green; Liver Circulation; Male; Middle Aged | 1986 |
24 other study(ies) available for 1,1,1-trifluoro-2-chloroethane and halothane
| Article | Year |
|---|---|
Computation of brain-blood partitioning of organic solutes via free energy calculations.
Topics: Animals; Blood-Brain Barrier; Brain; Cattle; Cells, Cultured; Endothelium, Vascular; Membrane Lipids; Microcirculation; Molecular Conformation; Molecular Structure; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Software; Solubility; Thermodynamics | 1996 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Halothane hepatotoxicity and the reduced derivative, 1,1,1-trifluoro-2-chloroethane.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Environmental Exposure; Halothane; Liver; Rats | 1977 |
Halothane reductive metabolism in an adult surgical population.
Topics: Adult; Aged; Anesthesia, Inhalation; Biotransformation; Breath Tests; Female; Fluorides; Halothane; Humans; Male; Middle Aged; Phenytoin | 1990 |
Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat.
Topics: Administration, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Halothane; Hydrocarbons, Halogenated; Hyperthyroidism; Liver Diseases; Male; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Trifluoroacetic Acid; Triiodothyronine | 1988 |
2-Chloro-1,1,1-trifluoroethane.
Topics: Animals; Chemical Phenomena; Chemistry; Female; Halothane; Humans; Male; Mutagenicity Tests; Rats | 1986 |
Metabolism of halothane in children having repeated halothane anaesthetics.
Topics: Adult; Anesthesia, Inhalation; Bromides; Child; Female; Halothane; Humans; Liver Function Tests; Male; Time Factors | 1987 |
Modulation of the reductive metabolism of halothane by microsomal cytochrome b5 in rat liver.
Topics: Anaerobiosis; Animals; Chlorofluorocarbons; Cytochrome b Group; Cytochromes b5; Electron Transport; Halothane; Hydrocarbons, Halogenated; Male; Malonates; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1987 |
Concentration-dependence of halothane metabolism in rabbits.
Topics: Animals; Bile; Chlorofluorocarbons; Ethane; Halothane; Male; Oxidation-Reduction; Rabbits; Trifluoroacetic Acid | 1986 |
Binding of halothane-free radicals to fatty acids following UV irradiation.
Topics: Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Ethane; Fatty Acids, Unsaturated; Free Radicals; Gas Chromatography-Mass Spectrometry; Halothane; Oleic Acids; Ultraviolet Rays | 1982 |
Reductive halothane metabolite formation and halothane binding in rat hepatic microsomes.
Topics: Animals; Chlorofluorocarbons; Cytochrome P-450 Enzyme System; Dithionite; Enflurane; Halothane; Hydrocarbons, Halogenated; Isoflurane; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1984 |
1-Chloro-2,2,2-trifluoroethyl radical: Formation from halothane by human cytochrome P-450 in reconstituted vesicles and binding to phospholipids.
Topics: Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Ethane; Halothane; Humans; Liposomes; Liver; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Phospholipids | 1981 |
One-electron reduction of halothane and formation of halide ions in aqueous solutions.
Topics: Antioxidants; Bromides; Chemical Phenomena; Chemistry; Fluorides; Gamma Rays; Halothane; Hydrogen-Ion Concentration; Oxidation-Reduction; Solutions; Water | 1983 |
The mechanism of reductive dehalogenation of halothane by liver cytochrome P450.
Topics: Animals; Biotransformation; Chlorofluorocarbons; Cytochrome P-450 Enzyme System; Halothane; Hydrocarbons, Halogenated; In Vitro Techniques; Liver; Male; Models, Chemical; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1982 |
Factors affecting the formation of chlorotrifluoroethane and chlorodifluoroethylene from halothane.
Topics: Animals; Chlorofluorocarbons; Cytochrome P-450 Enzyme System; Ethylenes; Halothane; Hydrocarbons, Halogenated; In Vitro Techniques; Male; Microsomes, Liver; Rats | 1981 |
Genetic differences in reductive metabolism and hepatotoxicity of halothane in three rat strains.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Enzyme Induction; Ethylenes; Genetic Variation; Halothane; Hydrocarbons, Halogenated; Hypoxia; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains | 1981 |
Time-course of formation of volatile reductive metabolites of halothane in humans and an animal model.
Topics: Adult; Animals; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Disease Models, Animal; Enzyme Induction; Ethylenes; Female; Halothane; Humans; Hydrocarbons, Halogenated; Kinetics; Male; Middle Aged; Phenobarbital; Rats; Rats, Inbred F344 | 1980 |
Identification and quantification of fluorine-containing metabolites of 1-chloro-2,2,2-trifluoroethane (HCFC133A) in the rat by 19F-NMR spectroscopy.
Topics: Animals; Biotransformation; Glucuronidase; Halothane; Magnetic Resonance Spectroscopy; Male; Oxidation-Reduction; Rats; Rats, Wistar | 1995 |
Metabolism of 1-fluoro-1,1,2-trichloroethane, 1,2-dichloro-1,1-difluoroethane, and 1,1,1-trifluoro-2-chloroethane.
Topics: Animals; Binding Sites; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Gas Chromatography-Mass Spectrometry; Halothane; Magnetic Resonance Spectroscopy; Male; Microsomes, Liver; Rats; Rats, Inbred F344 | 1995 |
Interaction of fluoroethane chlorofluorocarbon (CFC) substitutes with microsomal cytochrome P450. Stimulation of P450 activity and chlorodifluoroethene metabolism.
Topics: Animals; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cytochrome P-450 Enzyme System; Halothane; Hydrocarbons, Fluorinated; Male; Microsomes, Liver; NADP; Oxygen Consumption; Phenobarbital; Rabbits; Solubility | 1993 |
Isoflurane acts as an inhibitor of oxidative dehalogenation while acting as an accelerator of reductive dehalogenation of halothane in guinea pig liver microsomes.
Topics: Anesthetics, Inhalation; Animals; Chlorofluorocarbons; Cytochrome P-450 Enzyme System; Guinea Pigs; Halothane; Isoflurane; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxidoreductases; Spectrophotometry, Ultraviolet; Trifluoroacetic Acid | 1995 |
Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
Topics: Anesthetics, Inhalation; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Chlorofluorocarbons; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Halothane; Humans; In Vitro Techniques; Isoenzymes; Ketoconazole; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Recombinant Proteins | 1996 |
2-Chloro-1,1,1-trifluoroethane.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Halothane; Humans; Mutagenicity Tests; Mutagens; Neoplasms, Experimental; Salmonella typhimurium | 1999 |
Bioactivation and cytotoxicity of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) in isolated rat hepatocytes.
Topics: Animals; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cyclic N-Oxides; Dose-Response Relationship, Drug; Fomepizole; Gas Chromatography-Mass Spectrometry; Glutathione; Halothane; Hepatocytes; In Vitro Techniques; Ketones; L-Lactate Dehydrogenase; Male; Maleates; Nitrogen Oxides; Pyrazoles; Pyridines; Rats; Rats, Wistar; Troleandomycin | 2001 |