Page last updated: 2024-08-26

1,1'-ethylidene bis(tryptophan) and tryptophan

1,1'-ethylidene bis(tryptophan) has been researched along with tryptophan in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's30 (93.75)18.2507
2000's2 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belongia, EA; Gleich, GJ; Lin, F; Lundy, SK; Mayeno, AN1
Ashley, DL; Driskell, WJ; Grainger, J; Hill, RH; Mazzola, EP; Needham, LL; Page, SW; Sirimanne, SR1
Hosaki, Y; Ito, J; Sakimoto, K; Torigoe, Y1
Kashiwazaki, S; Miyasaka, N; Yamaoka, KA1
Kamatani, N1
Kasahara, T; Miura, Y; Shioiri-Nakano, K; Suda, T; Tsunoda, J; Yamaguchi, Y1
Aldhous, P1
Ames, MM; Foote, CS; Gleich, GJ; Hedberg, CW; Lin, F; Loegering, DA; Mayeno, AN1
Emslie-Smith, AM; Engel, AG; Gleich, GJ; Mayeno, AN; Nakano, S1
Page, SW; Thomas, FS; Trucksess, MW1
Fujita, K; Inuo, G; Kashiwazaki, S; Kolb, JP; Miyasaka, N; Saito, I; Yamaoka, KA1
Bingel, SA; Hampton, M; Harley, RA; Heyes, MP; Ludwicka, A; Maize, J; Ohba, T; Silver, RM; Smith, T1
Cosgrove, JW; Latham, PS; Mayeno, AN; Sidransky, H; Verney, E1
Avidor, R; Brenneman, DE; Burnet, P; Page, SW; Schultzberg, M; Sternberg, EM; Thomas, FS; Zelazowski, P1
Caudill, SP; Falk, H; Flanders, WD; Hill, RH; Kilbourne, EM; Needham, L; Philen, RM; Sampson, EJ; Sewell, L1
Trucksess, MW1
Crofford, LJ; Dugan, EM; Love, LA; Page, SW; Principato, MA; Rader, JI; Raybourne, RB; Smith, MJ; Trucksess, MW; Turner, ML1
Davidson, AG; Knight, BI1
Jin, Z; Kurihara, N; Wada, O; Yanagisawa, H1
Adachi, J; Naito, T; Ninomiya, I; Ogawa, Y; Tatsuno, Y; Ueno, Y1
Mayeno, AN; Varga, J; Vining, V; Zangrilli, JG1
Falanga, V; Greenberg, AS; Hasan, A; Hill, RH; Murata, H; Takagi, H1
Bolster, M; Hampton, M; Ludwicka, A; Maize, J; Silver, R; Suzuki, S; Tourkina, E1
Clauw, DJ1
Brown, WR1
Latham, P; Schwartz, A; Sidransky, H; Verney, E1
Adachi, J; Gomez, M; Smith, CC; Sternberg, EM; Tatsuno, Y; Ueno, Y1
Meyer, K; Simat, T; Steinhart, H; van Wickern, B1
Sidransky, H; Verney, E1
Bankhurst, AD; Buss, WC; Mayeno, AN; Pastuszyn, A; Peabody, D; Stepanek, J1
Barth, H; Berg, PA; Klein, R1
Rodgers, KJ; Shiozawa, N1

Reviews

3 review(s) available for 1,1'-ethylidene bis(tryptophan) and tryptophan

ArticleYear
Animal models of the eosinophilia-myalgia syndrome.
    The Journal of rheumatology. Supplement, 1996, Volume: 46

    Topics: Animals; Disease Models, Animal; Eosinophilia-Myalgia Syndrome; Macaca mulatta; Mice; Rats; Tryptophan

1996
Effects of tryptophan related compounds on nuclear regulatory control. Possible role in the eosinophilia-myalgia syndrome.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Alanine; Animals; Drug Contamination; Eosinophilia-Myalgia Syndrome; Humans; Liver; Nuclear Envelope; Proteins; Receptors, Cytoplasmic and Nuclear; RNA; Tryptophan

1996
Misincorporation of amino acid analogues into proteins by biosynthesis.
    The international journal of biochemistry & cell biology, 2008, Volume: 40, Issue:8

    Topics: Amino Acids; Amino Acids, Diamino; Aminoacylation; Animals; Bacteria; Canavanine; Ethionine; Humans; Levodopa; Lupus Erythematosus, Systemic; Oxidation-Reduction; Parkinson Disease; Plants; Protein Biosynthesis; Tryptophan

2008

Other Studies

29 other study(ies) available for 1,1'-ethylidene bis(tryptophan) and tryptophan

ArticleYear
3-(Phenylamino)alanine, a novel aniline-derived amino acid associated with the eosinophilia-myalgia syndrome: a link to the toxic oil syndrome?
    Mayo Clinic proceedings, 1992, Volume: 67, Issue:12

    Topics: Alanine; beta-Alanine; Brassica; Chromatography, High Pressure Liquid; Drug Contamination; Eosinophilia-Myalgia Syndrome; Fatty Acids, Monounsaturated; Plant Oils; Rapeseed Oil; Spain; Tryptophan; United States

1992
Identification of decomposition products of 1,1'-ethylidenebis [L-tryptophan], a compound associated with eosinophilia-myalgia syndrome.
    Bulletin of environmental contamination and toxicology, 1992, Volume: 48, Issue:5

    Topics: Chromatography, Liquid; Eosinophilia-Myalgia Syndrome; Gastric Juice; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Biological; Spectrum Analysis; Tryptophan

1992
Identification of substances formed by decomposition of peak E substance in tryptophan.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1992, Volume: 30, Issue:1

    Topics: Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Tryptophan

1992
L-tryptophan contaminant "peak E" and interleukin-5 production from T cells.
    Lancet (London, England), 1991, Dec-07, Volume: 338, Issue:8780

    Topics: Cells, Cultured; Dose-Response Relationship, Drug; Drug Contamination; In Vitro Techniques; Interleukin-5; Lymphocyte Activation; T-Lymphocytes; Tryptophan

1991
[Topics on eosinophilia-myalgia syndrome].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Nov-10, Volume: 80, Issue:11

    Topics: Adult; Animals; Bacillus; Drug Contamination; Eosinophilia-Myalgia Syndrome; Humans; Male; Reference Standards; Tryptophan

1991
Effect of synthesized constituents in the L-tryptophan product on the differentiation of eosinophils and the induction of IL-6: a possible cause of eosinophilia-myalgia syndrome.
    Biochemical and biophysical research communications, 1991, Aug-15, Volume: 178, Issue:3

    Topics: Bone Marrow; Bone Marrow Cells; Carbolines; Cell Differentiation; Edema; Eosinophilia; Eosinophils; Hematopoietic Stem Cells; Humans; Interleukin-1; Interleukin-2; Interleukin-6; Muscular Diseases; Reference Values; Syndrome; Tryptophan

1991
Biotechnology. Yellow light on L-tryptophan.
    Nature, 1991, Oct-10, Volume: 353, Issue:6344

    Topics: Animals; Eosinophilia-Myalgia Syndrome; Humans; Rats; Tryptophan

1991
Characterization of "peak E," a novel amino acid associated with eosinophilia-myalgia syndrome.
    Science (New York, N.Y.), 1990, Dec-21, Volume: 250, Issue:4988

    Topics: Chromatography, High Pressure Liquid; Eosinophilia; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Muscles; Pain; Spectrometry, Mass, Fast Atom Bombardment; Syndrome; Tryptophan

1990
1,1'-Ethylidenebis[tryptophan] induces pathologic alterations in muscle similar to those observed in the eosinophilia-myalgia syndrome.
    Neurology, 1994, Volume: 44, Issue:12

    Topics: Animals; Eosinophilia-Myalgia Syndrome; Female; Macrophages; Microcirculation; Muscles; Rats; Rats, Inbred Lew; Time Factors; Tryptophan

1994
High-performance liquid chromatographic determination of 1,1'-ethylidenebis(L-tryptophan) in L-tryptophan preparations.
    Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:5

    Topics: Buffers; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Solubility; Tryptophan

1994
1,1'-Ethylidenebis(tryptophan) (Peak E) induces functional activation of human eosinophils and interleukin 5 production from T lymphocytes: association of eosinophilia-myalgia syndrome with a L-tryptophan contaminant.
    Journal of clinical immunology, 1994, Volume: 14, Issue:1

    Topics: B-Lymphocytes; Base Sequence; Blood Proteins; Electrophoresis, Agar Gel; Eosinophil Granule Proteins; Eosinophilia-Myalgia Syndrome; Eosinophils; Humans; Interleukin-5; Lymphocyte Activation; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, Interleukin; Receptors, Interleukin-5; Ribonucleases; RNA, Messenger; Spleen; T-Lymphocytes; Tryptophan; Tumor Cells, Cultured

1994
A murine model of the eosinophilia-myalgia syndrome induced by 1,1'-ethylidenebis (L-tryptophan).
    The Journal of clinical investigation, 1994, Volume: 93, Issue:4

    Topics: Animals; Disease Models, Animal; Eosinophilia-Myalgia Syndrome; Fascia; Female; Mice; Mice, Inbred C57BL; Muscles; Quinolinic Acid; Tryptophan

1994
Studies with 1,1'-ethylidenebis(tryptophan), a contaminant associated with L-tryptophan implicated in the eosinophilia-myalgia syndrome.
    Toxicology and applied pharmacology, 1994, Volume: 126, Issue:1

    Topics: Animals; Eosinophilia-Myalgia Syndrome; Female; In Vitro Techniques; Liver; Nuclear Envelope; Proteins; Rats; Rats, Sprague-Dawley; Tritium; Tryptophan

1994
A decomposition product of a contaminant implicated in L-tryptophan eosinophilia myalgia syndrome affects spinal cord neuronal cell death and survival through stereospecific, maturation and partly interleukin-1-dependent mechanisms.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2

    Topics: Animals; Carbolines; Cell Death; Cell Survival; Cells, Cultured; Drug Contamination; Eosinophilia-Myalgia Syndrome; Female; Interleukin-1; Mice; Pregnancy; Receptors, Interleukin-1; Recombinant Proteins; Spinal Cord; Stereoisomerism; Tryptophan

1993
Tryptophan contaminants associated with eosinophilia-myalgia syndrome. The Eosinophilia-Myalgia Studies of Oregon, New York and New Mexico.
    American journal of epidemiology, 1993, Aug-01, Volume: 138, Issue:3

    Topics: Drug Contamination; Eosinophilia-Myalgia Syndrome; Humans; Tryptophan

1993
Separation and isolation of trace impurities in L-tryptophan by high-performance liquid chromatography.
    Journal of chromatography, 1993, Feb-05, Volume: 630, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Humans; Spectrophotometry, Ultraviolet; Tryptophan

1993
Pathological and immunological effects of ingesting L-tryptophan and 1,1'-ethylidenebis (L-tryptophan) in Lewis rats.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Female; Immunophenotyping; Inflammation; Leukocyte Count; Macrophages; Monocytes; Muscles; Necrosis; Pancreas; Rats; Rats, Inbred Lew; Receptors, Interleukin-2; Tryptophan

1993
Sensitive determination of 1,1'-ethylidenebis(L-tryptophan) in L-tryptophan by gradient HPLC with fluorimetric detection.
    Journal of pharmaceutical and biomedical analysis, 1993, Volume: 11, Issue:1

    Topics: Chromatography, High Pressure Liquid; Drug Contamination; Reference Standards; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry; Tryptophan

1993
Production of polyclonal antibodies against 1,1'-ethyliden bis[L-tryptophan] (EBT), a potential contaminant causing eosinophilia-myalgia syndrome (EMS).
    Toxicology letters, 1993, Volume: 66, Issue:3

    Topics: Animals; Antibody Formation; Binding Sites; Eosinophilia-Myalgia Syndrome; Immunization; Male; Molecular Weight; Rabbits; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet; Tryptophan

1993
Metabolism and distribution in the rat of peak E substance, a constituent in L-tryptophan product implicated in eosinophilia-myalgia syndrome.
    Archives of toxicology, 1993, Volume: 67, Issue:4

    Topics: Animals; Carbolines; Chromatography, High Pressure Liquid; Drug Contamination; Eosinophilia-Myalgia Syndrome; Male; Rats; Rats, Wistar; Tryptophan

1993
1,1'-Ethylidenebis[L-tryptophan], an impurity in L-tryptophan associated with eosinophilia-myalgia syndrome, stimulates type I collagen gene expression in human fibroblasts in vitro.
    Biochemistry and molecular biology international, 1995, Volume: 37, Issue:5

    Topics: Carbolines; Cell Division; Cells, Cultured; Collagen; Eosinophilia-Myalgia Syndrome; Extracellular Matrix; Fibroblasts; Gene Expression Regulation; Humans; Stimulation, Chemical; Tryptophan

1995
Delayed onset of skin fibrosis after the ingestion of eosinophilia-myalgia syndrome-associated L-tryptophan.
    Journal of the American Academy of Dermatology, 1996, Volume: 35, Issue:2 Pt 1

    Topics: Adult; Eosinophilia-Myalgia Syndrome; Female; Fibrosis; Hand Dermatoses; Humans; Leg Dermatoses; Skin; Tryptophan

1996
A contaminant of L-tryptophan enhances expression of dermal collagen in a murine model of eosinophilia myalgia syndrome.
    Proceedings of the Association of American Physicians, 1996, Volume: 108, Issue:4

    Topics: Animals; Blotting, Northern; Collagen; Disease Models, Animal; Eosinophilia-Myalgia Syndrome; Female; In Situ Hybridization; Mice; Mice, Inbred C57BL; RNA, Messenger; Tryptophan

1996
Comparative histopathologic evaluation of animal studies: murine studies with L-tryptophan and constitutents.
    The Journal of rheumatology. Supplement, 1996, Volume: 46

    Topics: Alanine; Animals; Drug Combinations; Mice; Mice, Inbred Strains; Muscle, Skeletal; Muscular Diseases; Skin; Skin Diseases; Tryptophan

1996
A comparative study of tissue distribution and excretion among three substances implicated in eosinophilia-myalgia syndrome.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Alanine; Animals; Biotransformation; Brain; Carbolines; Eosinophilia-Myalgia Syndrome; Humans; Kidney; Liver; Rats; Tissue Distribution; Tryptophan

1996
Synthesis and analysis of contaminants in ems-related tryptophan.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Alanine; Chromatography, High Pressure Liquid; Drug Contamination; Eosinophilia-Myalgia Syndrome; Humans; Tryptophan; Tryptophanase

1996
Mouse strain and source of L-tryptophan affects hepatic nuclear tryptophan binding.
    Toxicology, 1997, Mar-14, Volume: 118, Issue:1

    Topics: Alanine; Animals; Binding, Competitive; Cell Nucleus; Liver; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Inbred NZB; Protein Biosynthesis; Selenic Acid; Selenium Compounds; Sodium Selenite; Tryptophan

1997
EBT, a tryptophan contaminant associated with eosinophilia myalgia syndrome, is incorporated into proteins during translation as an amino acid analog.
    Autoimmunity, 1996, Volume: 25, Issue:1

    Topics: Animals; Cell-Free System; Electrophoresis, Polyacrylamide Gel; Eosinophilia-Myalgia Syndrome; Leucine; Protein Biosynthesis; Proteins; Rabbits; Reticulocytes; Tritium; Tryptophan

1996
L-tryptophan contaminant 'peak E' induces the release of IL-5 and IL-10 by peripheral blood mononuclear cells from patients with functional somatic syndromes.
    Clinical and experimental immunology, 2001, Volume: 126, Issue:2

    Topics: Adult; Case-Control Studies; Cytokines; Drug Contamination; Eosinophilia-Myalgia Syndrome; Female; Fibromyalgia; Humans; In Vitro Techniques; Interleukin-10; Interleukin-5; Leukocytes, Mononuclear; Male; Middle Aged; Risk Factors; Syndrome; Th2 Cells; Tryptophan

2001