1'-hydroxysafrole has been researched along with pentachlorophenol in 2 studies
*Pentachlorophenol: An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool. [MeSH]
*Pentachlorophenol: An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boberg, EW; Liem, A; Miller, EC; Miller, JA | 1 |
| Boberg, EW; Liem, A; Miller, EC; Miller, JA; Poland, A | 1 |
2 other study(ies) available for 1'-hydroxysafrole and pentachlorophenol
| Article | Year |
|---|---|
Inhibition by pentachlorophenol of the initiating and promoting activities of 1'-hydroxysafrole for the formation of enzyme-altered foci and tumors in rat liver.
Topics: Animals; Chick Embryo; Chlorophenols; Cocarcinogenesis; Diethylnitrosamine; Dioxoles; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Pentachlorophenol; Precancerous Conditions; Rats; Rats, Inbred Strains; Safrole | 1987 |
Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.
Topics: Animals; Carcinogens; Chlorophenols; Cytosol; Dioxoles; Female; Kinetics; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Pentachlorophenol; Phenotype; Rats; Safrole; Species Specificity; Sulfurtransferases | 1983 |