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1',2'-dihydrorotenone and rotenone

1',2'-dihydrorotenone has been researched along with rotenone in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's8 (44.44)18.2507
2000's2 (11.11)29.6817
2010's3 (16.67)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Ashack, RJ; Goodman, FR; Malek, RS; McCarty, LP; Peet, NP1
Attardi, G; Earley, FG; Patel, SD; Ragan, I1
Rosazza, JP; Sariaslani, FS1
Blandini, F; Greenamyre, JT; Porter, RH1
Jewess, PJ1
Blandini, F; Greenamyre, JT1
Greenamyre, JT; Higgins, DS1
Charalambous, A; Frey, KA; Greenamyre, JT; Higgins, DS; Kilbourn, MR; Sherman, P1
Blandini, F; Greenamyre, JT; Nappi, G1
Brandt, U; Lümmen, P; Okun, JG1
Lümmen, P1
Greenamyre, JT; Greene, JG; Higgins, DS; Talpade, DJ1
AMBROSE, AM; CHRISTENSEN, HE; RATHER, LJ1
Greenamyre, JT; Matsuno-Yagi, A; Miller, GW; Panov, AV; Richardson, JR; Seo, BB; Sherer, TB; Testa, CM; Yagi, T1
Cao, B; He, S; Li, J; Mao, X; Schimmer, AD; Tang, J; Zhang, J; Zhang, Z1
Billard, F; Felde, TZ; Grüneberg, WJ; Hubert, P; Lautié, E; Quetin-Leclercq, J; Rozet, E; Vandelaer, N1
Cao, B; Chen, G; Han, K; Mao, X; Xu, X; Zhang, J; Zhang, Z1
Kim, KK; Kim, SH; Lee, E; Lee, JA; Lee, KW; Yeo, SY1

Other Studies

18 other study(ies) available for 1',2'-dihydrorotenone and rotenone

ArticleYear
Evaluation of rotenone and related compounds as antagonists of slow-reacting substance of anaphylaxis.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:9

    Topics: Acetylcholine; Anaphylaxis; Animals; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Rotenone; Serotonin Antagonists; SRS-A

1980
Photolabelling of a mitochondrially encoded subunit of NADH dehydrogenase with [3H]dihydrorotenone.
    FEBS letters, 1987, Jul-13, Volume: 219, Issue:1

    Topics: Animals; Cattle; Cytochrome Reductases; Humans; Immunochemistry; Immunologic Techniques; Mitochondria, Heart; NADH Dehydrogenase; Photochemistry; Protein Binding; Rotenone

1987
Biotransformations of 1',2'-dihydrorotenone by Streptomyces griseus.
    Applied and environmental microbiology, 1985, Volume: 49, Issue:2

    Topics: Biotransformation; Magnetic Resonance Spectroscopy; Rotenone; Streptomyces griseus

1985
Autoradiographic study of mitochondrial complex I and glutamate receptors in the basal ganglia of rats after unilateral subthalamic lesion.
    Neuroscience letters, 1995, Feb-17, Volume: 186, Issue:2-3

    Topics: Animals; Autoradiography; Basal Ganglia; Dizocilpine Maleate; Histocytochemistry; Male; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Rotenone; Thalamic Nuclei

1995
Insecticides and acaricides which act at the rotenone-binding site of mitochondrial NADH:ubiquinone oxidoreductase; competitive displacement studies using a 3H-labelled rotenone analogue.
    Biochemical Society transactions, 1994, Volume: 22, Issue:1

    Topics: Animals; Binding Sites; Binding, Competitive; Flight, Animal; Insecta; Insecticides; Kinetics; Mitochondria, Muscle; NAD(P)H Dehydrogenase (Quinone); Rotenone; Tritium; Ubiquinone

1994
Assay of [3H]dihydrorotenone binding to complex I in intact human platelets.
    Analytical biochemistry, 1995, Sep-01, Volume: 230, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Adult; Blood Platelets; Diffusion; Female; Humans; Male; NAD(P)H Dehydrogenase (Quinone); Radioligand Assay; Rotenone; Solubility; Tritium; Water

1995
[3H]dihydrorotenone binding to NADH: ubiquinone reductase (complex I) of the electron transport chain: an autoradiographic study.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Jun-15, Volume: 16, Issue:12

    Topics: 1-Methyl-4-phenylpyridinium; Adenine Nucleotides; Animals; Autoradiography; Brain; Electron Transport; Entorhinal Cortex; Insecticides; Male; Mitochondria; N-Methylaspartate; NAD; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley; Rotenone; Sensitivity and Specificity; Tritium

1996
Intrastriatal neurotoxin injections reduce in vitro and in vivo binding of radiolabeled rotenoids to mitochondrial complex I.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Binding, Competitive; Corpus Striatum; Injections; Male; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Nerve Tissue Proteins; Neurotoxins; Protein Binding; Quinolinic Acid; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rotenone

1997
Quantitative study of mitochondrial complex I in platelets of parkinsonian patients.
    Movement disorders : official journal of the Movement Disorder Society, 1998, Volume: 13, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Aged; Aged, 80 and over; Blood Platelets; Case-Control Studies; Dopamine Agents; Dose-Response Relationship, Drug; Electron Transport Complex I; Female; Humans; Insecticides; Male; Middle Aged; Mitochondria; NADH, NADPH Oxidoreductases; Neurotoxins; Parkinson Disease; Radioligand Assay; Rotenone

1998
Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase).
    The Journal of biological chemistry, 1999, Jan-29, Volume: 274, Issue:5

    Topics: Animals; Binding Sites; Cattle; Enzyme Inhibitors; Furans; Kinetics; Muscidae; NAD(P)H Dehydrogenase (Quinone); Pyridines; Pyrimidines; Quinazolines; Rotenone; Spectrometry, Fluorescence

1999
Biochemical aspects of N-heterocyclic complex-I inhibitors with insecticidal activity.
    Biochemical Society transactions, 1999, Volume: 27, Issue:4

    Topics: Animals; Binding Sites; Dose-Response Relationship, Drug; Electron Transport Complex I; Enzyme Inhibitors; Houseflies; Insecticides; Kinetics; Mitochondria, Muscle; NADH, NADPH Oxidoreductases; Pyrimidines; Rotenone; Ubiquinone

1999
In vivo labeling of mitochondrial complex I (NADH:ubiquinone oxidoreductase) in rat brain using [(3)H]dihydrorotenone.
    Journal of neurochemistry, 2000, Volume: 75, Issue:6

    Topics: Animals; Autoradiography; Binding, Competitive; Brain; Electron Transport Complex I; Electron Transport Complex II; Kidney; Liver; Male; Malonates; Microinjections; Mitochondria; Multienzyme Complexes; Myocardium; NADH, NADPH Oxidoreductases; Neurodegenerative Diseases; Organ Specificity; Oxidoreductases; Rats; Rats, Sprague-Dawley; Rotenone; Sodium Azide; Succinate Dehydrogenase; Tissue Distribution; Tritium

2000
Toxicological and pharmacological studies on dihydrorotenone.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1953, Volume: 42, Issue:6

    Topics: Humans; Insecticides; Rotenone

1953
Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease.
    Journal of neurochemistry, 2007, Volume: 100, Issue:6

    Topics: Adenosine Triphosphate; alpha-Tocopherol; Animals; Animals, Newborn; Antioxidants; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Electron Transport Complex I; Humans; In Vitro Techniques; Male; Mesencephalon; Mitochondria; NADH Dehydrogenase; Neuroblastoma; Pesticides; Protein Carbonylation; Rats; Rats, Inbred Lew; Rotenone; Saccharomyces cerevisiae Proteins; Tyrosine 3-Monooxygenase

2007
The natural pesticide dihydrorotenone induces human plasma cell apoptosis by triggering endoplasmic reticulum stress and activating p38 signaling pathway.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Apoptosis; Cell Line; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondrial Proteins; p38 Mitogen-Activated Protein Kinases; Pesticides; Phosphorylation; Plasma Cells; Rotenone; Unfolded Protein Response

2013
Fast method for the simultaneous quantification of toxic polyphenols applied to the selection of genotypes of yam bean (Pachyrhizus sp.) seeds.
    Talanta, 2013, Dec-15, Volume: 117

    Topics: Chromatography, High Pressure Liquid; Discriminant Analysis; Genotype; Limit of Detection; Microwaves; Pachyrhizus; Polyphenols; Principal Component Analysis; Reference Standards; Rotenone; Seeds; Solid Phase Extraction; Time Factors

2013
Natural pesticide dihydrorotenone arrests human plasma cancer cells at the G0/G1 phase of the cell cycle.
    Journal of biochemical and molecular toxicology, 2014, Volume: 28, Issue:5

    Topics: Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Cyclin D2; Cyclin-Dependent Kinases; G1 Phase; Humans; Insecticides; Molecular Structure; Plasma Cells; Resting Phase, Cell Cycle; Reverse Transcriptase Polymerase Chain Reaction; Rotenone; Signal Transduction

2014
New screening system using Twist1 promoter activity identifies dihydrorotenone as a potent drug targeting cancer-associated fibroblasts.
    Scientific reports, 2020, 04-27, Volume: 10, Issue:1

    Topics: Apoptosis; Blotting, Western; Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Nuclear Proteins; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Rotenone; Twist-Related Protein 1

2020