1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with vanadates in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 17 (73.91) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisher, J; Hankins, WD; Isaacs, MA; Spivak, JL | 1 |
| Inoue, T; Morita, T; Okuhama, R; Sera, M; Tominaga, N; Ueki, H | 1 |
| Huang, CK; Laramee, GR | 1 |
| Atkins, KB; Troen, BR | 1 |
| Lanius, RA; Pasqualotto, BA; Shaw, CA | 1 |
| Kosaka, C; Masuda, J; Ogata, J; Sasaguri, T; Zen, K | 1 |
| Almazan, G; Radhakrishna, M | 1 |
| Huang, RW; Takatsuki, K; Tsuda, H | 1 |
| Greenwel, P; Hu, W; Kohanski, RA; Ramirez, F | 1 |
| Petersen, MM; Steadman, R; Williams, JD | 1 |
| Fink, BD; Grunwald, GB; Lee, MM | 1 |
| Lochter, A; Schachner, M | 1 |
| Bergelson, LD; Krifuks, O; Schlesinger, M | 1 |
| Cantabrana, B; Hidalgo, A; Pérez-Vallina, JR | 1 |
| Gebert, CA; Park, SH; Waxman, DJ | 2 |
| Isoherranen, K; Jansen, C; Punnonen, K; Uotila, P | 1 |
| Anouar, Y; Castel, H; Cazin, L; Le Foll, F; Louiset, E; Vaudry, H | 1 |
| Collins, JF; Ghishan, FK; Hines, ER; Kiela, PR | 1 |
| Balabanova, L; Fedinec, AL; Leffler, CW; Parfenova, H; Sullivan, CD; Wang, X | 1 |
| Bahar, H; Binderman, I; Yaffe, A | 1 |
| Li, DL; Li, YJ; Sun, WP; Xiao, FC; Zhang, LB; Zhou, SS; Zhou, YM | 1 |
| Chambers, LJ; Michel, AD; Walter, DS | 1 |
23 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and vanadates
| Article | Year |
|---|---|
Protein kinases and phosphatases are involved in erythropoietin-mediated signal transduction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Division; Cells, Cultured; Erythropoiesis; Erythropoietin; Genistein; In Vitro Techniques; Isoflavones; Isoquinolines; Mice; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Piperazines; Protein Kinases; Protein Tyrosine Phosphatases; Signal Transduction; Staurosporine; Vanadates; Zinc | 1992 |
Stimulatory effect of vanadate on 3',5'-cyclic guanosine monophosphate-inhibited low Michaelis-Menten constant 3',5'-cyclic adenosine monophosphate phosphodiesterase activity in isolated rat fat pads.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Alkaloids; Amiloride; Animals; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Insulin; Isoquinolines; Kinetics; Male; Microsomes; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Staurosporine; Vanadates | 1992 |
Stimulation of a histone H4 protein kinase in Triton X-100 lysates of rabbit peritoneal neutrophils pretreated with chemotactic factors: effect of leukotriene B4 and cytochalasin B.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cytochalasin B; Detergents; Egtazic Acid; Enzyme Activation; Histones; In Vitro Techniques; Isoquinolines; Kinetics; Leukotriene B4; Neutrophils; Octoxynol; Phosphorylation; Piperazines; Polyethylene Glycols; Protamine Kinase; Rabbits; Vanadates | 1991 |
Phorbol ester stimulated cathepsin L expression in U937 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cathepsin L; Cathepsins; Cell Differentiation; Cycloheximide; Cysteine Endopeptidases; Drug Interactions; Endopeptidases; Enzyme Induction; Humans; Isoquinolines; Lymphoma, Large B-Cell, Diffuse; Monocytes; Neoplasm Proteins; Piperazines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vanadates | 1995 |
A novel mechanism of AMPA receptor regulation: ionically triggered kinases and phosphatases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Chlorides; Glycerophosphates; Ibotenic Acid; In Vitro Techniques; Isoquinolines; Peptides; Phosphoric Monoester Hydrolases; Piperazines; Potassium; Protein Kinase Inhibitors; Protein Kinases; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Sodium; Tamoxifen; Vanadates | 1993 |
Gene expression of monocyte chemoattractant protein-1 in human monocytes is regulated by cell density through protein tyrosine kinase and protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Benzoquinones; Blotting, Northern; Cell Division; Cell Nucleus; Cells, Cultured; Chemokine CCL2; Chemotactic Factors; Cytokines; Gene Expression Regulation; Genistein; Humans; Isoflavones; Isoquinolines; Lactams, Macrocyclic; Monocytes; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Sulfonamides; Transcription, Genetic; Vanadates | 1994 |
Protein kinases mediate basic fibroblast growth factor's stimulation of proliferation and c-fos induction in oligodendrocyte progenitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Biomarkers; Brain; Brain Stem; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Gene Expression; Genes, fos; Genistein; Immunohistochemistry; Isoflavones; Isoquinolines; Kinetics; Oligodendroglia; Piperazines; Protein Kinase C; Protein Kinases; Rats; Rats, Sprague-Dawley; Stem Cells; Tetradecanoylphorbol Acetate; Time Factors; Vanadates | 1994 |
Role of protein phosphorylation in EPO-mediated early signal transduction: analysis in the EPO-reactive cell line ELM-I-1 transfected with a c-fos-enhancer/promoter-luciferase reporter gene.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Benzoquinones; Cell Line; Erythropoietin; Genes, fos; Hydroquinones; In Vitro Techniques; Isoquinolines; Lactams, Macrocyclic; Luciferases; Mice; Phosphoproteins; Piperazines; Promoter Regions, Genetic; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; Signal Transduction; Staurosporine; Vanadates | 1994 |
Tyrosine dephosphorylation of nuclear proteins mimics transforming growth factor beta 1 stimulation of alpha 2(I) collagen gene expression.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cells, Cultured; Collagen; Enzyme Inhibitors; Ethers, Cyclic; Fetus; Fibroblasts; Gene Expression; Genistein; Humans; Isoflavones; Isoquinolines; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphotyrosine; Piperazines; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Skin; Staurosporine; Transcription, Genetic; Transforming Growth Factor beta; Vanadates | 1995 |
Human neutrophil secondary granule exocytosis is independent of protein kinase activation and is modified by calmodulin activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Bucladesine; Calmodulin; Cytoplasmic Granules; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Genistein; Humans; Isoflavones; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vanadates | 1996 |
Evidence that tyrosine phosphorylation regulates N-cadherin turnover during retinal development.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain; Cadherins; Chick Embryo; Enzyme Inhibitors; Heart; Hydrogen Peroxide; Isoquinolines; Lens, Crystalline; Myocardium; Organ Culture Techniques; Peptide Mapping; Phosphorylation; Phosphoserine; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Retina; Sulfonamides; Tyrosine; Vanadates | 1997 |
Inhibitors of protein kinases abolish ECM-mediated promotion of neuronal polarity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Benzophenanthridines; Bucladesine; Cell Polarity; Cells, Cultured; Cyclic AMP; Dibutyryl Cyclic GMP; Embryo, Mammalian; Enzyme Inhibitors; Extracellular Matrix; Extracellular Matrix Proteins; Hippocampus; Neurites; Neurons; Phenanthridines; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Signal Transduction; Vanadates | 1997 |
The down-modulation of CD4 induced by the GM1 ganglioside is regulated by phosphatases and kinases: evidence from enzyme inhibitors and anti-CD45 antibodies.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies, Monoclonal; CD4 Antigens; CD4-Positive T-Lymphocytes; Down-Regulation; Enzyme Inhibitors; G(M1) Ganglioside; Gangliosides; Genistein; Humans; In Vitro Techniques; Leukocyte Common Antigens; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphoprotein Phosphatases; Phytohemagglutinins; Protein Kinase Inhibitors; Staurosporine; Vanadates | 1998 |
Contribution of cAMP to the inhibitory effect of non-steroidal anti-inflammatory drugs in rat uterine smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cyclic AMP; Edetic Acid; Enzyme Inhibitors; Female; In Vitro Techniques; Mefenamic Acid; Muscle Contraction; Muscle, Smooth; Pertussis Toxin; Protein Kinase Inhibitors; Rats; Rats, Wistar; Thionucleotides; Uterus; Vanadates; Virulence Factors, Bordetella | 1998 |
Termination of growth hormone pulse-induced STAT5b signaling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Cycloheximide; Cysteine Endopeptidases; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Growth Hormone; Janus Kinase 2; Leupeptins; Liver; Milk Proteins; Multienzyme Complexes; Phosphorylation; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Receptors, Somatotropin; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Vanadates | 1999 |
Down-regulation of liver JAK2-STAT5b signaling by the female plasma pattern of continuous growth hormone stimulation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Down-Regulation; Electrophoresis; Female; Genistein; Growth Hormone; Growth Inhibitors; Janus Kinase 2; Leupeptins; Liver; Male; Milk Proteins; Protein Synthesis Inhibitors; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Signal Transduction; STAT5 Transcription Factor; Staurosporine; Trans-Activators; Vanadates | 1999 |
Ultraviolet irradiation induces cyclooxygenase-2 expression in keratinocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcysteine; Adult; Antioxidants; Blotting, Northern; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Enzyme Inhibitors; Epidermis; Gene Expression; Genistein; Humans; Hydrogen Peroxide; Immunohistochemistry; Isoenzymes; Keratinocytes; Male; Membrane Proteins; Oxidants; Phosphoprotein Phosphatases; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein-Tyrosine Kinases; RNA, Messenger; Ultraviolet Rays; Vanadates | 1999 |
Regulation of GABAA receptor by protein tyrosine kinases in frog pituitary melanotrophs.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Cells, Cultured; Enzyme Inhibitors; Evoked Potentials; gamma-Aminobutyric Acid; Genistein; Patch-Clamp Techniques; Phenols; Pituitary Gland; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Rana ridibunda; Receptors, GABA-A; Sulfonamides; Vanadates | 2000 |
Regulation of the rat NHE3 gene promoter by sodium butyrate.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Butyrates; Caco-2 Cells; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Volatile; Genes, Reporter; Humans; Hydroxamic Acids; Okadaic Acid; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Transcription, Genetic; Vanadates | 2001 |
Regulation of CO production in cerebral microvessels of newborn pigs.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aminolevulinic Acid; Animals; Animals, Newborn; Calcium; Calcium Signaling; Capillaries; Carbon Monoxide; Catalysis; Cerebrovascular Circulation; Cytosol; Enzyme Inhibitors; Genistein; Heme; Heme Oxygenase (Decyclizing); In Vitro Techniques; Ionomycin; Ionophores; Phosphorylation; Photosensitizing Agents; Swine; Tetradecanoylphorbol Acetate; Tyrphostins; Vanadates | 2003 |
Topical application of drugs influencing cytoskeleton and cell contractility affects alveolar bone loss in rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alveolar Bone Loss; Analysis of Variance; Animals; Chelating Agents; Cytochalasin D; Cytoskeleton; Edetic Acid; Enzyme Inhibitors; Male; Mandibular Diseases; Maxillary Diseases; Nucleic Acid Synthesis Inhibitors; Rats; Rats, Wistar; Vanadates | 2006 |
Effects of monocarboxylic acid-derived Cl- channel blockers on depolarization-activated potassium currents in rat ventricular myocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiogenesis Inhibitors; Animals; Chloride Channels; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Genistein; Isoquinolines; Myocytes, Cardiac; Niflumic Acid; Nitrobenzoates; Patch-Clamp Techniques; Phenols; Potassium Channels; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides; Vanadates | 2007 |
Negative and positive allosteric modulators of the P2X(7) receptor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Allosteric Regulation; Animals; Binding Sites; Cell Line; Dose-Response Relationship, Drug; Ethidium; Glycine; Humans; Molecular Structure; Piperazines; Protein Conformation; Pyridoxal Phosphate; Quinolines; Radioligand Assay; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Recombinant Proteins; Species Specificity; Time Factors; Transfection; Vanadates | 2008 |