1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with tretinoin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.64) | 18.7374 |
| 1990's | 16 (72.73) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Baldassare, JJ; Burns, D; Ceska, M; Fisher, GJ; Hammerberg, C; Henderson, PA; Voorhees, JJ; Zhang, QY | 1 |
| Cara, A; Cornaglia-Ferraris, P; Pecorara, M | 1 |
| Harada, N; Koike, T; Morikawa, M; Yoshida, T | 1 |
| Hurme, M; Matikainen, S; Serkkola, E | 1 |
| Collen, D; Nelles, L; Thompson, EA | 1 |
| Kato, Y; Mochizuki, T; Okazaki, T; Sawada, H; Tashima, M; Uchino, H | 1 |
| Chapekar, MS; Glazer, RI; Hartman, KD; Knode, MC | 1 |
| Fujita, T; Katakami, Y; Koizumi, T; Matsui, T; Nakao, Y | 1 |
| Sauro, MD; Zorn, NE | 1 |
| Arai, T; Irino, S; Kawanishi, K; Kiuchi, H; Takahara, J; Tanaka, T; Taoka, T; Yamaoka, G | 1 |
| Jääskeläinen, T; Mäenpää, PH; Pirskanen, A | 1 |
| Chiu, R; Evans, RM; Gachelin, G; Kitabayashi, I; Umesono, K; Yokoyama, K | 1 |
| Audette, M; Bouillon, M | 2 |
| Abita, JP; Chedeville, A; Gespach, C; Zimber, A | 1 |
| Bouzinba-Segard, H; Castagna, M; Fan, XT; Perderiset, M | 1 |
| Dautrevaux, M; Formstecher, P; Lefebvre, P; Tahayato, A | 1 |
| Byers, DM; Cook, HW; Mandla, SG; Ridgway, ND | 1 |
| Ronca, F; Yee, KS; Yu, VC | 1 |
| Abita, JP; Barbu, V; Chedeville, A; Gespach, C; Zimber, A | 1 |
| Chung, SW; Kang, SN; Kim, TS | 1 |
22 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and tretinoin
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Retinoic acid and phorbol ester synergistically up-regulate IL-8 expression and specifically modulate protein kinase C-epsilon in human skin fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blotting, Western; Cells, Cultured; Cyclic AMP; Drug Synergism; Enzyme Activation; Fibroblasts; Gene Expression; Humans; In Vitro Techniques; Interleukin 1 Receptor Antagonist Protein; Interleukin-8; Isoquinolines; Phosphoproteins; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Proteins; RNA, Messenger; Sialoglycoproteins; Skin; Sulfonamides; Tetradecanoylphorbol Acetate; Tretinoin | 1992 |
Analysis of CD4 gene expression in human fetal brain and neuroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Base Sequence; Brain; CD4 Antigens; Cell Differentiation; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gestational Age; Humans; Isoquinolines; Molecular Sequence Data; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Piperazines; Poly A; RNA, Messenger; RNA, Neoplasm; Tretinoin; Tumor Cells, Cultured | 1992 |
Regulation of myeloid-specific calcium binding protein synthesis by cytosolic protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Northern; Calcitriol; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Cell Differentiation; Cytosol; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Isoquinolines; Leukemia; Mice; Mice, Inbred BALB C; Piperazines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tretinoin; Tumor Cells, Cultured | 1992 |
Retinoic acid enhances IL-1 beta expression in myeloid leukemia cells and in human monocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blotting, Northern; Bucladesine; Gene Expression; Humans; Interleukin-1; Isoquinolines; Leukemia, Myeloid; Lipopolysaccharides; Monocytes; Piperazines; Protein Kinase Inhibitors; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1991 |
Effect of retinoic acid on the synthesis of tissue-type plasminogen activator and plasminogen activator inhibitor-1 in human endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cells, Cultured; Diterpenes; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; Humans; Isoquinolines; Molecular Probe Techniques; Piperazines; Plasminogen Inactivators; Protein Kinase Inhibitors; Retinyl Esters; RNA, Messenger; Tissue Plasminogen Activator; Tretinoin; Vitamin A | 1991 |
Staurosporine, a novel protein kinase inhibitor, enhances HL-60-cell differentiation induced by various compounds.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Bucladesine; Calcitriol; Cell Differentiation; Dose-Response Relationship, Drug; Drug Synergism; Humans; Isoquinolines; Piperazines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1988 |
Synergistic effect of retinoic acid and calcium ionophore A23187 on differentiation, c-myc expression, and membrane tyrosine kinase activity in human promyelocytic leukemia cell line HL-60.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Calmodulin; Cell Differentiation; Cell Line; Cell Membrane; Drug Synergism; Gene Expression Regulation; Hematopoiesis; Humans; Isoquinolines; Leukemia, Myeloid, Acute; Piperazines; Protein-Tyrosine Kinases; Proto-Oncogenes; RNA, Messenger; Sulfonamides; Tretinoin; Trifluoperazine | 1987 |
Inhibition of phorbol ester-induced phenotypic differentiation of HL-60 cells by 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine, a protein kinase inhibitor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Antibodies, Monoclonal; Antigens, Surface; Calcitriol; Calcium; Cell Differentiation; Cell Line; Cytosol; Humans; Isoquinolines; Phorbol Esters; Piperazines; Protein Kinase Inhibitors; Thiazolidinediones; Tretinoin | 1986 |
Retinoic acid induces translocation of protein kinase C (PKC) and activation of nuclear PKC (nPKC) in rat splenocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antibodies, Monoclonal; Biological Transport; Cell Nucleus; Cytosol; Enzyme Activation; Isoquinolines; Lymphocytes; Male; Nuclear Proteins; Phosphorylation; Piperazines; Protein Kinase C; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Sphingosine; Spleen; Staurosporine; Tretinoin | 1995 |
Alkaline phosphatase activity in the human promyelocytic leukemia cell line, HL-60, induced by retinoic acid and recombinant human granulocyte colony-stimulating factor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaline Phosphatase; Alkaloids; Calcitriol; Cell Line; Enzyme Induction; Granulocyte Colony-Stimulating Factor; Humans; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Piperazines; Protein Kinase C; Recombinant Proteins; Staurosporine; Tretinoin; Tumor Cells, Cultured | 1993 |
Effects of transforming growth factor beta 1 on the regulation of osteocalcin synthesis in human MG-63 osteosarcoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Base Sequence; Bone Neoplasms; Calcitriol; Cell Division; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Molecular Sequence Data; Oligonucleotide Probes; Osteocalcin; Osteosarcoma; Phosphorylation; Piperazines; Protein Kinase C; Receptors, Calcitriol; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta; Tretinoin; Tumor Cells, Cultured; Vitamin D-Binding Protein | 1994 |
A novel pathway for retinoic acid-induced differentiation of F9 cells that is distinct from receptor-mediated trans-activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Differentiation; Genes, jun; Isoquinolines; Mice; Phosphoproteins; Piperazines; Protein Kinase Inhibitors; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Staurosporine; Teratocarcinoma; Time Factors; Transcriptional Activation; Tretinoin; Tumor Cells, Cultured | 1994 |
Retinoic acid-stimulated intercellular adhesion molecule-1 expression on SK-N-SH cells: calcium/calmodulin-dependent pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Adhesion Molecules; Enzyme Activation; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Interferon-gamma; Isoquinolines; Neuroblastoma; Piperazines; Protein Kinase C; Sulfonamides; Terpenes; Thapsigargin; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 1994 |
Inhibition of proliferation and induction of monocytic differentiation on HL60 human promyelocytic leukemia cells treated with bile acids in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bile Acids and Salts; Cell Cycle; Cell Differentiation; Cell Division; Chenodeoxycholic Acid; Deoxycholic Acid; Flow Cytometry; Humans; Isoquinolines; Leukemia, Promyelocytic, Acute; Lithocholic Acid; Monocytes; Piperazines; Protein Kinase C; Sphingosine; Tretinoin; Tumor Cells, Cultured | 1994 |
Synergy between phorbol esters and retinoic acid in inducing protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain; Chlorpromazine; Cytosol; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Isoquinolines; Kinetics; Phosphorylation; Piperazines; Protein Binding; Protein Kinase C; Rats; Sulfonamides; Tetradecanoylphorbol Acetate; Tretinoin; Trifluoperazine; Tritium | 1994 |
Transduction of retinoic acid and gamma-interferon signal for intercellular adhesion molecule-1 expression on human tumor cell lines: evidence for the late-acting involvement of protein kinase C inactivation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cell Adhesion Molecules; Enzyme Activation; Glioma; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Isoquinolines; Neuroblastoma; Piperazines; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1993 |
A protein kinase C-dependent activity modulates retinoic acid-induced transcription.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Cell Line; Cell Nucleus; Chlorocebus aethiops; DNA; Enzyme Induction; Humans; Indoles; Isoenzymes; Isoquinolines; Maleimides; Molecular Sequence Data; Phosphorylation; Piperazines; Promoter Regions, Genetic; Protein Binding; Protein Kinase C; Protein Processing, Post-Translational; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin | 1993 |
Differential alterations of ethanolamine and choline phosphoglyceride metabolism by clofibrate and retinoic acid in human fibroblasts are not mediated by phorbol ester-sensitive protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinogens; Clofibrate; Enzyme Inhibitors; Ethanolamine; Ethanolamines; Fibroblasts; Humans; Hypolipidemic Agents; Isoquinolines; Phosphatidylcholines; Phospholipids; Protein Kinase C; Skin; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1996 |
Retinoic acid confers resistance to p53-dependent apoptosis in SH-SY5Y neuroblastoma cells by modulating nuclear import of p53.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; DNA Fragmentation; Drug Resistance; Etoposide; Fluorescent Antibody Technique; Gamma Rays; Humans; Neuroblastoma; Nuclear Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tretinoin; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1999 |
Functional interactions between bile acids, all-trans retinoic acid, and 1,25-dihydroxy-vitamin D3 on monocytic differentiation and myeloblastin gene down-regulation in HL60 and THP-1 human leukemia cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bile Acids and Salts; Calcitriol; Cell Cycle; Cell Differentiation; Cell Division; Down-Regulation; Gene Expression Regulation; HL-60 Cells; Humans; Monocytes; Myeloblastin; Protein Kinase C; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Tretinoin | 2000 |
Capsaicin potentiates 1,25-dihydoxyvitamin D3- and all-trans retinoic acid-induced differentiation of human promyelocytic leukemia HL-60 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Benzophenanthridines; Calcitriol; Capsaicin; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Flavonoids; HL-60 Cells; Humans; Indoles; Maleimides; Phenanthridines; Protein Kinase C; Signal Transduction; Tretinoin | 2001 |