1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with thymidine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (16.13) | 18.7374 |
| 1990's | 26 (83.87) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chua, BH; Chua, CC; Diglio, CA; Krebs, CJ | 1 |
| Berridge, MV; Tan, AS | 1 |
| Calle, R; Naftolin, F; Robbins, R; Tranque, PA | 1 |
| Kelleher, D; Long, A | 2 |
| He, CJ; Meulders, Q; Peraldi, MN; Rebibou, JM; Rondeau, E | 1 |
| Cao, XM; Guy, GR; Sukhatme, VP; Tan, YH | 1 |
| Dell'Era, P; Presta, M; Ragnotti, G; Rusnati, M; Tiberio, L | 1 |
| Sauro, MD; Zorn, NE | 1 |
| Kennedy, AR; Su, LN; Toscano, WA | 1 |
| Fujiwara, K; Hirata, K | 1 |
| Lau, LF; Lee, CM; Xu, H | 1 |
| Atluru, D; Atluru, S; Polam, S; Woloschak, GE | 1 |
| Ardaillou, R; Baud, L; Cherqui, G; Cragoe, EJ; Perez, J | 1 |
| Fan, SG; Lee, CM; Xu, H | 1 |
| Hidaka, H; Kawakami, K; Ohmura, T; Onoue, K; Yamamoto, Y | 1 |
| Craven, PA; DeRubertis, FR | 1 |
| Cragoe, EJ; Dexter, TM; Heyworth, CM; Monk, PN; Vallance, SJ; Whetton, AD | 1 |
| Hügel, U; Klaus, G; May, T; Mayer, H; Mehls, O; Ritz, E; von Eichel, B | 1 |
| Cheng, JF; Leu, SJ; Singh, VK | 1 |
| Aoyagi, T; Eguchi, K; Kawabe, Y; Migita, K; Nagataki, S; Tsukada, T | 1 |
| Goto, R; Ibuki, Y | 1 |
| Emerling, D; Hashimoto, Y; Horie, Y; Kinoshita, M; Kurokawa, K; Nakao, A; Tsukamoto, K; Watanabe, T | 1 |
| Horio, T; Ikeda, M; Johchi, M; Kohno, M; Kurihara, N; Takeda, T; Yasunari, K | 1 |
| Abboud, HE; Biswas, P; Choudhury, GG; Grandaliano, G | 1 |
| Lewis, CE; McGee, JO; Pusztai, L | 1 |
| Baba, A; Hayashi, M; Hosoi, R; Matsuda, T; Murata, Y; Takuma, K; Tamada, K; Tanaka, K | 1 |
| Jimi, N; Minami, K; Sata, T; Segawa, K; Shigematsu, A | 1 |
| Dobson, JG; Ethier, MF | 1 |
| Mei, C; Pattison, TA; Sahai, A; Tannen, RL | 1 |
| Imokawa, G; Kimura, M; Morisaki, N; Yada, Y | 1 |
31 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and thymidine
| Article | Year |
|---|---|
Endothelin stimulates protein synthesis in smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Cytidine; DNA; Dose-Response Relationship, Drug; Endothelins; Insulin; Isoquinolines; Male; Muscle, Smooth, Vascular; Piperazines; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Inbred WKY; RNA; Thymidine | 1992 |
The protein kinase C inhibitor, calphostin C, inhibits succinate-dependent mitochondrial reduction of MTT by a mechanism that does not involve protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow; Carbazoles; Cell Division; Cell Line; Coloring Agents; DNA Replication; Indoles; Isoquinolines; Kinetics; Mice; Mice, Inbred C3H; Mitochondria; Naphthalenes; Oxidation-Reduction; Piperazines; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Succinates; Tetrazolium Salts; Thiazoles; Thymidine | 1992 |
Involvement of protein kinase-C in the mitogenic effect of insulin-like growth factor-I on rat astrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Astrocytes; Cells, Cultured; Drug Combinations; Insulin-Like Growth Factor I; Isoquinolines; Mitogens; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate; Thymidine | 1992 |
Development and characterization of a protein kinase C beta-isozyme-deficient T-cell line.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Western; Cell Differentiation; Cell Division; Cell Line; Flow Cytometry; Humans; Interleukin-2; Isoenzymes; Isoquinolines; Phenotype; Piperazines; Protein Kinase C; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymidine | 1992 |
Growth factor-like effect of urokinase type plasminogen activator in human renal cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Division; Cells, Cultured; DNA Replication; Growth Substances; Humans; Isoquinolines; Kidney Glomerulus; Kinetics; Pertussis Toxin; Piperazines; Plasminogen Activators; Plasminogen Inactivators; Protein Kinase C; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Tetradecanoylphorbol Acetate; Thymidine; Urokinase-Type Plasminogen Activator; Virulence Factors, Bordetella | 1991 |
Regulation of the Egr-1 gene by tumor necrosis factor and interferons in primary human fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Blotting, Northern; Blotting, Western; DNA; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; HeLa Cells; Humans; Interferon-gamma; Isoquinolines; Kinetics; Mice; Phosphorylation; Piperazines; RNA, Messenger; Staurosporine; Sulfonamides; Thymidine; Tumor Necrosis Factor-alpha | 1992 |
Basic fibroblast growth factor requires a long-lasting activation of protein kinase C to induce cell proliferation in transformed fetal bovine aortic endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antibodies; Aorta; Cattle; Cell Division; Cell Line, Transformed; Endothelium, Vascular; Enzyme Activation; Fibroblast Growth Factor 2; Isoquinolines; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine; Time Factors | 1991 |
Prolactin induces proliferation of vascular smooth muscle cells through a protein kinase C-dependent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Division; Cells, Cultured; Cyclosporins; DNA; Enzyme Activation; Isoquinolines; Muscle, Smooth, Vascular; Piperazines; Platelet-Derived Growth Factor; Prolactin; Protein Kinase C; Receptors, Prolactin; Sphingosine; Staurosporine; Thymidine; Tritium | 1991 |
Suppression of phorbol ester-enhanced radiation-induced malignancy in vitro by protease inhibitors is independent of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cytosol; DNA Replication; Isoquinolines; Kinetics; Mice; Mice, Inbred C3H; Piperazines; Protease Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine; Time Factors; Tosylphenylalanyl Chloromethyl Ketone; X-Rays | 1991 |
Possible contribution of protein kinase C activation to priming for DNA synthesis induced by epidermal growth factor with insulin and its inhibition by plasma membrane in primary cultured rat hepatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channel Blockers; Cell Membrane; Cells, Cultured; DNA; DNA Replication; Enzyme Activation; Epidermal Growth Factor; Insulin; Isoquinolines; Liver; Male; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Vasopressins | 1990 |
Synergistic effect of phorbol myristate acetate on bacterial lipopolysaccharide induced rat splenocyte proliferation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Division; Drug Synergism; In Vitro Techniques; Isoquinolines; Lipopolysaccharides; Male; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Spleen; Tetradecanoylphorbol Acetate; Thymidine; Time Factors | 1990 |
Regulation of mitogen-stimulated human T-cell proliferation, interleukin-2 production, and interleukin-2 receptor expression by protein kinase C inhibitor, H-7.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Division; Humans; In Vitro Techniques; Interleukin-2; Interleukin-4; Isoquinolines; Lymphocyte Activation; Phytohemagglutinins; Piperazines; Protein Kinase C; Receptors, Interleukin-2; RNA, Messenger; Sulfonamides; T-Lymphocytes; Thymidine; Tritium | 1990 |
Leukotriene D4-induced proliferation of glomerular epithelial cells: PKC- and Na+-H+ exchanger-mediated response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Carrier Proteins; Cell Division; Cells, Cultured; DNA Replication; Epithelial Cells; Epithelium; Humans; Isoquinolines; Kidney Glomerulus; Kinetics; Piperazines; Protein Kinase C; Sodium-Hydrogen Exchangers; SRS-A; Thymidine | 1989 |
The protein kinase C inhibitor H-7 inhibits concanavalin A induced T-lymphocyte activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Concanavalin A; In Vitro Techniques; Isoquinolines; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Mitogens; Piperazines; Protein Kinase C; Signal Transduction; Spleen; T-Lymphocytes; Thymidine | 1989 |
Induction and regulation of human interleukin 2 gene expression: significance of protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Enzyme Activation; Gene Expression Regulation; Humans; Interleukin-2; Isoquinolines; Lymphocytes; Mitoguazone; Ornithine; Phytohemagglutinins; Piperazines; Prostaglandins E; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymidine | 1986 |
Role of activation of protein kinase C in the stimulation of colonic epithelial proliferation by unsaturated fatty acids.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Cell Division; Colon; Diglycerides; DNA; Enzyme Activation; Epithelial Cells; Fatty Acids, Unsaturated; Female; Inositol Phosphates; Isoquinolines; Linoleic Acid; Linoleic Acids; Oleic Acid; Oleic Acids; Ornithine Decarboxylase; Palmitic Acid; Palmitic Acids; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Thymidine | 1988 |
Interleukin-3-stimulated haemopoietic stem cell proliferation. Evidence for activation of protein kinase C and Na+/H+ exchange without inositol lipid hydrolysis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Division; Cell Line; Enzyme Activation; Hematopoietic Stem Cells; Hydrogen-Ion Concentration; Inositol Phosphates; Interleukin-3; Isoquinolines; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine | 1988 |
Synergistic effects of parathyroid hormone and 1,25-dihydroxyvitamin D3 on proliferation and vitamin D receptor expression of rat growth cartilage cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcitriol; Cell Division; Cells, Cultured; Cyclic AMP; Cycloheximide; Dactinomycin; DNA; Drug Synergism; Growth Plate; Isoquinolines; Parathyroid Hormone; Peptide Fragments; Piperazines; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Calcitriol; Tetradecanoylphorbol Acetate; Thymidine; Tritium | 1994 |
Effect of substance P and protein kinase inhibitors on beta-amyloid peptide-induced proliferation of cultured brain cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amyloid beta-Peptides; Animals; Animals, Newborn; Brain; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Isoquinolines; Kinetics; Piperazines; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Substance P; Sulfonamides; Thymidine | 1994 |
The role of protein kinase in human synovial fibroblast growth.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arthritis, Rheumatoid; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cells, Cultured; Fibroblast Growth Factor 2; Fibroblasts; Genistein; Humans; Hyperplasia; Isoflavones; Isoquinolines; Kinetics; Lactams, Macrocyclic; Piperazines; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Signal Transduction; Synovial Membrane; Thymidine | 1995 |
Adaptive response to low doses of gamma-ray in Chinese hamster cells: determined by cell survival and DNA synthesis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adaptation, Physiological; Animals; Cell Survival; CHO Cells; Colony-Forming Units Assay; Cricetinae; DNA; Gamma Rays; Isoquinolines; Piperazines; Protein Kinase C; Signal Transduction; Thymidine | 1994 |
Prostaglandin F2 alpha enhances tyrosine phosphorylation and DNA synthesis through phospholipase C-coupled receptor via Ca(2+)-dependent intracellular pathway in NIH-3T3 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Calcium; Dinoprost; DNA; Ionomycin; Isoquinolines; Mice; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Receptors, Prostaglandin; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Type C Phospholipases; Tyrosine | 1994 |
Conventional protein kinase C isoforms are not essential for cellular proliferation of a T cell lymphoma line.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Division; Cell Line; DNA, Neoplasm; Flow Cytometry; Humans; Isoenzymes; Isoquinolines; Kinetics; Lymphoma, T-Cell; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine; Tritium; Tumor Cells, Cultured | 1993 |
Interaction of PDGF and natriuretic peptides on mesangial cell proliferation and endothelin secretion.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Atrial Natriuretic Factor; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Endothelins; Glomerular Mesangium; Isoquinolines; Kinetics; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Nitroprusside; Piperazines; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Thymidine; Transforming Growth Factor beta | 1993 |
Involvement of PKC-alpha in PDGF-mediated mitogenic signaling in human mesangial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Division; Cells, Cultured; DNA; Enzyme Activation; Gene Expression; Glomerular Mesangium; Humans; Isoenzymes; Isoquinolines; Kinetics; Piperazines; Platelet-Derived Growth Factor; Protein Kinase C; RNA, Messenger; Signal Transduction; Thymidine; Time Factors | 1993 |
Growth arrest of the breast cancer cell line, T47D, by TNF alpha; cell cycle specificity and signal transduction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Cycle; Cell Division; DNA, Neoplasm; Ethers, Cyclic; Humans; Isoquinolines; Okadaic Acid; Piperazines; Protein Kinase C; Sensitivity and Specificity; Signal Transduction; Stimulation, Chemical; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Involvement of Na+,K(+)ATPase in the mitogenic effect of insulin-like growth factor-I on cultured rat astrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Astrocytes; Bucladesine; Cells, Cultured; DNA; Insulin; Insulin-Like Growth Factor I; Isoquinolines; Mitogens; Ouabain; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Thymidine | 1996 |
Inhibitory effect of the intravenous anesthetic, ketamine, on rat mesangial cell proliferation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anesthetics, Intravenous; Angiotensin II; Animals; Cell Count; Cell Division; Cells, Cultured; Cyclic AMP; Cytokines; Depression, Chemical; Glomerular Mesangium; Ketamine; Male; Propofol; Protein Kinase Inhibitors; Rats; Rats, Wistar; Thymidine | 1997 |
Adenosine stimulation of DNA synthesis in human endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Endothelium, Vascular; Humans; Kinetics; Poly A; Purinergic P1 Receptor Antagonists; Quinazolines; Tetradecanoylphorbol Acetate; Thioinosine; Thionucleotides; Thymidine; Triazoles; Umbilical Veins | 1997 |
Chronic hypoxia induces proliferation of cultured mesangial cells: role of calcium and protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cell Division; Cell Hypoxia; Cell Membrane; Cells, Cultured; Cytosol; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Kinetics; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Thymidine | 1997 |
Biological characterization of human fibroblast-derived mitogenic factors for human melanocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Cellular Senescence; Culture Media, Conditioned; Culture Media, Serum-Free; Cytokines; DNA; Enzyme Inhibitors; Fibroblast Growth Factor 2; Fibroblasts; Genistein; Growth Substances; Hepatocyte Growth Factor; Humans; Interleukin-1; Kinetics; Lactams, Macrocyclic; Melanocytes; Phloretin; Protein-Tyrosine Kinases; Quinones; Rifabutin; Skin; Stem Cell Factor; Thymidine | 1998 |