1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with thromboxane a2 in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 10 (83.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiyotani, A; Isono, K; Kondo, M; Konno, K; Sakai, N; Tamaoki, J | 1 |
| Asano, T; Hidaka, H; Ikegaki, I; Satoh, S; Shibuya, M; Sugita, K; Suzuki, Y | 1 |
| Boucheix, C; Carroll, RC; Worthington, RE | 1 |
| Ferro, T; Hocking, D; Johnson, A; Phillips, P; Tsan, MF | 1 |
| Boehm, A; Halushka, PV; Mais, DE | 1 |
| Craven, PA; DeRubertis, FR; Studer, RK | 1 |
| Chan, CF; Chang, YL; Jiang, MJ | 1 |
| Kozawa, O; Oiso, Y; Shinoda, J; Suzuki, A | 1 |
| Takano, S | 1 |
| Ebina, S; Nakahata, N; Nakanishi, H; Yamamoto, K | 1 |
| Chua, BH; Chua, CC; Hamdy, RC | 1 |
| Hashimoto, Y; Higashihara, M; Kurokawa, K; Satoh, H; Sunaga, S; Togo, M; Watanabe, T | 1 |
12 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and thromboxane a2
| Article | Year |
|---|---|
Thromboxane A2 mimetic U46619 stimulates ciliary motility of rabbit tracheal epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cilia; Cyclic AMP; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Fatty Acids, Unsaturated; Hydrazines; Isoproterenol; Isoquinolines; Male; Movement; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Rabbits; Thromboxane A2; Trachea; Verapamil | 1992 |
Endothelin: a potential modulator of cerebral vasospasm.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cerebral Arteries; Dogs; Endothelins; Female; Ischemic Attack, Transient; Isoquinolines; Male; Muscle Contraction; Thromboxane A2 | 1990 |
Stimulus-response coupling in human platelets activated by monoclonal antibodies to the CD9 antigen, a 24 kDa surface-membrane glycoprotein.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Aspirin; Blood Platelets; Calcium; Collagen; Humans; Hydrogen-Ion Concentration; Immunoglobulin Fab Fragments; Isoquinolines; Membrane Glycoproteins; Phosphoproteins; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Kinase C; Serotonin; Signal Transduction; Tetraspanin 29; Thromboxane A2 | 1990 |
Protein kinase inhibitor prevents pulmonary edema in response to H2O2.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Capillary Permeability; Cytoskeleton; Endothelium, Vascular; Female; Guinea Pigs; Hydrogen Peroxide; Imidazoles; Isoquinolines; Male; Piperazines; Protein Kinase C; Pulmonary Artery; Pulmonary Edema; Thromboxane A2; Thromboxane-A Synthase | 1989 |
Polymyxin B increases TXA2/PGH2 agonist and antagonist affinities in human platelet membranes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Fatty Acids, Unsaturated; Humans; Hydrazines; In Vitro Techniques; Isoquinolines; Piperazines; Polymyxin B; Polymyxins; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins H; Protein Kinase Inhibitors; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Thromboxane A2 | 1988 |
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kidney Glomerulus; Kinetics; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphates; Phosphorylation; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Thromboxane A2 | 1994 |
Intracellular calcium and myosin light chain phosphorylation during U46619-activated vascular contraction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Guinea Pigs; In Vitro Techniques; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myosins; Naphthalenes; Phosphorylation; Piperazines; Polycyclic Compounds; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents | 1994 |
Thromboxane A2-stimulated phospholipase D in osteoblast-like cells: possible involvement of PKC.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Division; Cell Line; Choline; DNA; Isoquinolines; Mice; Naphthalenes; Osteoblasts; Phospholipase D; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1995 |
Staurosporine inhibits STA2-induced platelet aggregation by inhibition of myosin light-chain phosphorylation in rabbit washed platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Blood Platelets; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Isoquinolines; Kinetics; Myosins; Phosphoproteins; Phosphorylation; Piperazines; Platelet Aggregation; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Staurosporine; Thromboxane A2 | 1994 |
A protein kinase C with divalent cations contributes to thromboxane A2-induced contraction in rabbit vascular smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cells, Cultured; Edetic Acid; Female; Isoquinolines; Magnesium; Male; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Piperazines; Protein Kinase C; Rabbits; Thromboxane A2; Vasoconstriction | 1995 |
Regulation of endothelin-1 production by a thromboxane A2 mimetic in rat heart smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Endothelins; Fatty Acids, Unsaturated; Gene Expression; Hydrazines; Isoquinolines; Muscle, Smooth; Myocardium; Piperazines; Promoter Regions, Genetic; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Rats; Receptors, Thromboxane; RNA, Messenger; Thromboxane A2 | 1996 |
Protein kinase C plays a key role in the cross-talk between intracellular signalings via prostanoid receptors in a megakaryoblastic cell line, MEG-01s.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Calcium; Cell Line; Cyclic AMP; Dinoprostone; Hematopoietic Stem Cells; Humans; Iloprost; Ionomycin; Megakaryocytes; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Prostaglandin; Receptors, Thrombin; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1996 |