1-(5-isoquinolinesulfonyl)-2-methylpiperazine and tacrolimus

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with tacrolimus in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amano, H; Ito, M; Tomono, M; Toyoshima, K1
Adachi, M; Imai, K; Minami, Y; Miyazaki, T; Reed, JC; Sekiya, M; Takayama, S; Taniguchi, T; Torigoe, T1
Alam, T; Hamawy, MM; Knechtle, SJ; Manthei, ER; Tsuchida, M1
Hishinuma, S; Ogura, K1
Honma, Y; Kasukabe, T; Okabe-Kado, J; Yamamoto-Yamaguchi, Y1
Fukushi, H; Morishima, Y; Shirasaki, Y; Takano, H1
Cameron, P; Kanke, T; Macfarlane, SR; McKenzie, RC; Plevin, R; Sloss, CM1

Other Studies

7 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and tacrolimus

ArticleYear
Calcineurin is essential for DNA synthesis in Swiss 3T3 fibroblasts.
    The Biochemical journal, 1996, Aug-01, Volume: 317 ( Pt 3)

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Animals; Calcineurin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin-Binding Proteins; Cell Survival; Cyclosporine; DNA Replication; Enzyme Inhibitors; Extracellular Space; Fibroblast Growth Factors; Isoquinolines; Lysophospholipids; Mice; Phosphoprotein Phosphatases; Piperazines; Signal Transduction; Tacrolimus

1996
Interleukin-2 (IL-2) upregulates BAG-1 gene expression through serine-rich region within IL-2 receptor beta c chain.
    Blood, 1996, Dec-01, Volume: 88, Issue:11

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Carrier Proteins; Cell Line; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation; Genistein; Hematopoietic Stem Cells; Humans; Interleukin-2; Isoflavones; Janus Kinase 3; Lymphocytes; Mice; Phosphorylation; Phytohemagglutinins; Polyenes; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-bcl-2; Receptors, Interleukin-2; RNA, Messenger; Serine; Signal Transduction; Sirolimus; Stimulation, Chemical; Tacrolimus; Transcription Factors; Transfection

1996
T cell activation up-regulates the expression of the focal adhesion kinase Pyk2: opposing roles for the activation of protein kinase C and the increase in intracellular Ca2+.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Dec-15, Volume: 163, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; CD28 Antigens; Cell Adhesion Molecules; Cyclosporine; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Humans; Intracellular Fluid; Ionophores; Jurkat Cells; Lymphocyte Activation; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic; Up-Regulation

1999
Ca(2+)/calmodulin-mediated regulation of the desensitizing process in G(q) protein-coupled histamine H(1) receptor-mediated Ca(2+) responses in human U373 MG astrocytoma cells.
    Journal of neurochemistry, 2000, Volume: 75, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Astrocytoma; Calcineurin Inhibitors; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cyclosporine; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Histamine; Histamine H1 Antagonists; Humans; Kinetics; Okadaic Acid; Piperidines; Pyrilamine; Ranitidine; Receptors, Histamine H1; Sulfonamides; Tacrolimus; Tumor Cells, Cultured

2000
Induction of differentiation of human myeloid leukemia cells by immunosuppressant macrolides (rapamycin and FK506) and calcium/calmodulin-dependent kinase inhibitors.
    Experimental hematology, 2001, Volume: 29, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Enzyme Inhibitors; HL-60 Cells; Humans; Immunophilins; Immunosuppressive Agents; K562 Cells; Leukemia, Myeloid; Neoplasm Proteins; Protein Serine-Threonine Kinases; Sirolimus; Sulfonamides; Tacrolimus; Tacrolimus Binding Proteins; Tumor Cells, Cultured; U937 Cells

2001
Calmodulin and calmodulin-dependent kinase II mediate neuronal cell death induced by depolarization.
    Brain research, 2003, Feb-07, Volume: 962, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Death; Cells, Cultured; Cerebral Cortex; Egtazic Acid; Enzyme Inhibitors; Fetus; Kinetics; Membrane Potentials; Neurons; NG-Nitroarginine Methyl Ester; Nifedipine; Nitriles; Pyrethrins; Rats; Sulfonamides; Tacrolimus; Trifluoperazine; Veratridine

2003
The role of intracellular Ca2+ in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes.
    British journal of pharmacology, 2005, Volume: 145, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Cell Line; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Estrenes; Humans; I-kappa B Kinase; Indoles; Keratinocytes; Maleimides; Mitogen-Activated Protein Kinases; NF-kappa B; Oligonucleotides; Phosphodiesterase Inhibitors; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; Pyrrolidinones; Receptor, PAR-2; Signal Transduction; Tacrolimus; Tetradecanoylphorbol Acetate; Trypsin; Type C Phospholipases

2005