1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with substance p in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bitar, KN; Cease, KB; Hailat, N; Kaminski, MS; Strahler, JR | 1 |
| Putney, JW; Sugiya, H | 1 |
| Coderre, TJ; Yashpal, K | 1 |
| Cheng, JF; Leu, SJ; Singh, VK | 1 |
| Golard, A; Role, L; Siegelbaum, SA | 1 |
| Grillner, S; Parker, D; Svensson, E | 1 |
| Chakder, S; Rattan, S | 1 |
| Gu, YZ; Guan, BC; Li, ZW; Yang, YL; Yao, KH | 1 |
| Li, CX; Li, ZW; Si, JQ; Wang, LF; Yang, YL; Zhang, ZQ | 1 |
| Ko, JA; Nishida, T; Yanai, R | 1 |
10 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and substance p
| Article | Year |
|---|---|
Hsp27 is a mediator of sustained smooth muscle contraction in response to bombesin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anal Canal; Animals; Antibodies, Monoclonal; Bombesin; Cell Membrane Permeability; Electrophoresis, Gel, Two-Dimensional; Heat-Shock Proteins; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoquinolines; Muscle Contraction; Muscle, Smooth; Phosphates; Phosphorus Radioisotopes; Piperazines; Protein Kinase C; Rabbits; Substance P; Sulfonamides | 1991 |
Protein kinase C-dependent and -independent mechanisms regulating the parotid substance P receptor as revealed by differential effects of protein kinase C inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbazoles; Indole Alkaloids; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoquinolines; Male; Parotid Gland; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Sugar Phosphates | 1988 |
Intracellular messengers contributing to persistent nociception and hyperalgesia induced by L-glutamate and substance P in the rat formalin pain model.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arginine; Dexamethasone; Formaldehyde; Glutamic Acid; Hyperalgesia; Injections, Spinal; Isoquinolines; Male; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain; Pain Measurement; Pain Threshold; Piperazines; Protein Kinase C; Rats; Reflex; Substance P | 1994 |
Effect of substance P and protein kinase inhibitors on beta-amyloid peptide-induced proliferation of cultured brain cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amyloid beta-Peptides; Animals; Animals, Newborn; Brain; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Isoquinolines; Kinetics; Piperazines; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Substance P; Sulfonamides; Thymidine | 1994 |
Substance P potentiates calcium channel modulation by somatostatin in chick sympathetic ganglia.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channels; Cells, Cultured; Chick Embryo; Drug Synergism; Electrophysiology; Ganglia, Sympathetic; Isoquinolines; Kinetics; Patch-Clamp Techniques; Phosphorylation; Piperazines; Protein Kinase C; Somatostatin; Substance P | 1994 |
Substance P modulates sensory action potentials in the lamprey via a protein kinase C-mediated reduction of a 4-aminopyridine-sensitive potassium conductance.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Action Potentials; Adenylate Cyclase Toxin; Alkaloids; Animals; Benzophenanthridines; Cadmium Chloride; Electric Stimulation; Enzyme Inhibitors; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Lampreys; Male; Neurons; Notochord; Peptides; Pertussis Toxin; Phenanthridines; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C; Protein Kinases; Spinal Cord; Substance P; Tetraethylammonium; Thionucleotides; Virulence Factors, Bordetella; Wasp Venoms | 1997 |
Mechanisms and sites of action of endothelins 1 and 2 on the opossum internal anal sphincter smooth muscle tone in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic Agents; Anal Canal; Animals; Atropine; Calcium Channel Blockers; Calmodulin; Cyclooxygenase Inhibitors; Endothelin-1; Endothelin-2; Enzyme Inhibitors; Guanethidine; In Vitro Techniques; Indomethacin; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nitric Oxide Synthase; Nitroarginine; omega-Conotoxin GVIA; Opossums; Peptides; Polymethacrylic Acids; Protein Kinase C; Substance P; Sulfonamides; Tachyphylaxis; Tetrodotoxin | 1999 |
Three kinds of current in response to substance P in bullfrog DRG neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analgesics; Analysis of Variance; Androstanes; Animals; Barium; Benzimidazoles; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electric Conductivity; Electrophysiology; Enzyme Inhibitors; Ganglia, Spinal; Guanosine Diphosphate; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rana catesbeiana; Reaction Time; Substance P; Thionucleotides | 2003 |
Modulatory effect of substance P on GABA-activated currents from rat dorsal root ganglion.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Separation; Female; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Sprague-Dawley; Substance P | 2004 |
Up-regulation of ZO-1 expression and barrier function in cultured human corneal epithelial cells by substance P.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Claudin-1; DNA Primers; Electric Impedance; Epithelium, Corneal; Humans; Membrane Proteins; Neurokinin-1 Receptor Antagonists; Occludin; Phosphoproteins; Physalaemin; Substance P; Tight Junctions; Up-Regulation; Zonula Occludens-1 Protein | 2009 |