1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with sq-23377 in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (15.56) | 18.7374 |
| 1990's | 31 (68.89) | 18.2507 |
| 2000's | 6 (13.33) | 29.6817 |
| 2010's | 1 (2.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castrén, E; Hartikka, J; Lindholm, D; Thoenen, H; Zafra, F | 1 |
| Desai, SN; Letts, GL; Myers, CL; Schembri-King, J; Wallace, RW | 1 |
| Chao, R; Hannun, YA; Khan, W | 1 |
| Frizzell, RA; Worrell, RT | 1 |
| Chakrabarti, R; Engleman, EG; Gowda, SD; Mohagheghpour, N; Stein, BS | 1 |
| Celada, A; Maki, RA | 1 |
| Francis, J; Pon, DJ; Qu, Y; Sen, AK; Torchia, J | 1 |
| Auffredou, MT; Chaouchi, N; Galanaud, P; Leca, G; Sharma, S; Taieb, J; Vazquez, A | 1 |
| Abboud, CN; Lichtman, MA; Packman, CH; Sham, RL | 1 |
| Gimbrone, MA; Hrbolich, JK; Schafer, AI; Zavoico, GB | 1 |
| Iwata, K; Sasaki, Y | 1 |
| Dean, WL; Klein, JB; McLeish, KR; Schepers, TM; Sonnenfeld, G | 1 |
| Gnegy, ME; Mangels, LA | 1 |
| Lichtman, MA; Segel, GB; Woodlock, TJ | 1 |
| Christiansen, NO; Larsen, CS | 1 |
| Krebs, B; Kurrle, R; Rehermann, B; Resch, K; Szamel, M | 1 |
| Dougherty, RW; Niedel, JE; Rider, LG | 1 |
| Adamo, S; Cavallo, G; Frati, L; Gismondi, A; Paolini, R; Piccoli, M; Procopio, AD; Santoni, A | 1 |
| Caramelo, C; Schrier, RW; Tsai, P | 1 |
| Furuya, W; Grinstein, S | 1 |
| Walters, JD; Wojcik, MS | 1 |
| Di Virgilio, F; Foresta, C; Rossato, M | 1 |
| Chik, CL; Ho, AK; Inukai, T | 1 |
| Itoh, M; Joh, T; Kato, T; Miyamoto, T; Moriyama, A; Okayama, N; Suzuki, T; Takeuchi, T | 1 |
| Distler, A; Haller, H; Lindschau, C; Luft, FC; Quass, P | 1 |
| Itoh, M; Joh, T; Kato, T; Miyamoto, T; Okayama, N | 1 |
| Emerling, D; Hashimoto, Y; Horie, Y; Kinoshita, M; Kurokawa, K; Nakao, A; Tsukamoto, K; Watanabe, T | 1 |
| Mitchell, R; Thomson, FJ | 1 |
| Dana, R; Leto, TL; Levy, R; Malech, HL | 1 |
| Johnson, MS; MacEwan, DJ; Mitchell, R; Thomson, FJ | 1 |
| Gobran, LI; Griese, M; Rooney, SA | 1 |
| Rothstein, TL; Wang, Z; Xie, H | 1 |
| Hashimoto, Y; Higashihara, M; Kurokawa, K; Satoh, H; Sunaga, S; Togo, M; Watanabe, T | 1 |
| Sjöholm, A | 1 |
| Puschner, B; Schacht, J | 1 |
| Ciereszko, RE; Guan, Z; Ottobre, AC; Ottobre, JS; Petroff, BK; Stokes, BT | 1 |
| Hafner, M; Kox, WJ; Petzelt, C; Schmehl, W; Taschenberger, G | 1 |
| Jope, RS; Pacheco, MA | 1 |
| Howard, EW; Parizi, M; Tomasek, JJ | 1 |
| Aikawa, R; Hayashi, D; Komuro, I; Kudoh, S; Mizukami, M; Nagai, R; Shibasaki, F; Shiojima, I; Toko, H; Yazaki, Y; Zhu, W; Zou, Y | 1 |
| Bigdai, EV; Samoilov, VO | 1 |
| Balabanova, L; Fedinec, AL; Leffler, CW; Parfenova, H; Sullivan, CD; Wang, X | 1 |
| Allen, JC; Kahn, AM; Kone, BC; Yang, Y; Zhang, S | 1 |
| Hellsten, Y; Jensen, L; Kusuhara, K; Madsen, K; Pilegaard, H | 1 |
| Huang, WJ; Lin, TY; Lu, CW; Wang, SJ | 1 |
45 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and sq-23377
| Article | Year |
|---|---|
Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Glutamates; Glutamic Acid; Growth Substances; Hippocampus; Ionomycin; Isoquinolines; Kainic Acid; Kinetics; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Nifedipine; Norepinephrine; Piperazines; Potassium; Protein Kinase Inhibitors; Quisqualic Acid; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Discriminatory effects of protein kinase inhibitors and calcium ionophore on endothelial ICAM-1 induction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Calcimycin; Cell Adhesion Molecules; Cell Survival; Cytokines; Drug Synergism; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Ionomycin; Isoquinolines; Lipopolysaccharides; Piperazines; Protein Biosynthesis; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Cell Division; Cell Line; Ceramides; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Humans; Ionomycin; Isomerism; Isoquinolines; Molecular Weight; Naphthalenes; Okadaic Acid; Phosphorylation; Piperazines; Polycyclic Compounds; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase C; Retinoblastoma Protein; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate | 1992 |
CaMKII mediates stimulation of chloride conductance by calcium in T84 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Chloride Channels; Colon; Imidazoles; Ion Channels; Ionomycin; Isoquinolines; Kinetics; Membrane Proteins; Peptide Fragments; Phloretin; Piperazines; Protein Kinase C; Protein Kinases; Sphingosine; Trifluoperazine | 1991 |
Early activation events render T cells susceptible to HIV-1-induced syncytia formation. Role of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcium; CD3 Complex; CD4 Antigens; Cell Fusion; Cholera Toxin; Giant Cells; HIV-1; Humans; Ionomycin; Isoquinolines; Lymphocyte Activation; Piperazines; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes | 1991 |
IFN-gamma induces the expression of the genes for MHC class II I-A beta and tumor necrosis factor through a protein kinase C-independent pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow Cells; Calcimycin; Calmodulin; Gene Expression Regulation; Histocompatibility Antigens Class II; Interferon-gamma; Ionomycin; Isoquinolines; Macrophages; Major Histocompatibility Complex; Mice; Mice, Inbred DBA; Piperazines; Protein Kinase C; RNA, Messenger; Sphingosine; Sulfonamides; Tetradecanoylphorbol Acetate; Trifluoperazine; Tumor Necrosis Factor-alpha | 1991 |
Carbachol-stimulated phosphorylation of a 170-kDa endogenous protein in avian salt gland cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Atropine; Carbachol; Ducks; Ionomycin; Isoquinolines; Kinetics; Molecular Weight; Phosphates; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Proteins; Salt Gland; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Differential inhibition of interleukin 2- and interleukin 4-mediated human B cell proliferation by ionomycin: a possible regulatory role for apoptosis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; B-Lymphocytes; Calcium; Cell Death; DNA Damage; Humans; In Vitro Techniques; Interleukin-2; Interleukin-4; Interleukin-6; Ionomycin; Isoquinolines; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C | 1991 |
Signal transduction and the regulation of actin conformation during myeloid maturation: studies in HL60 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Bryostatins; Calcium; Cell Differentiation; Dimethyl Sulfoxide; Fluorescent Antibody Technique; Humans; In Vitro Techniques; Ionomycin; Isoquinolines; Lactones; Macrolides; Microscopy, Electron, Scanning; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperazines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Enhancement of thrombin- and ionomycin-stimulated prostacyclin and platelet-activating factor production in cultured endothelial cells by a tumor-promoting phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Arachidonic Acids; Calcimycin; Cells, Cultured; Dinoprost; Dinoprostone; Endothelium, Vascular; Epoprostenol; Humans; Ionomycin; Isoquinolines; Phorbol Esters; Phospholipases A; Phospholipases A2; Piperazines; Platelet Activating Factor; Prostaglandin D2; Prostaglandins H; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Concanavalin A- and fetal-calf-serum-induced rounding and myosin light chain phosphorylation in cultured smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Blood; Calcimycin; Calcium; Cells, Cultured; Chickens; Concanavalin A; Culture Media; Cytochalasin B; Cytochalasins; Diltiazem; Egtazic Acid; Gizzard, Avian; Ionomycin; Isoquinolines; Kinetics; Muscle, Smooth; Muscle, Smooth, Vascular; Myosin Subfragments; Phosphorylation; Rabbits; Verapamil | 1990 |
Role of intracellular calcium concentration and protein kinase C activation in IFN-gamma stimulation of U937 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Differentiation; Antigens, Differentiation, Myelomonocytic; Antigens, Surface; Biological Transport; Calcium; Cell Compartmentation; Cell Line; Enzyme Activation; Gallic Acid; HLA-DR Antigens; Humans; Inositol 1,4,5-Trisphosphate; Interferon-gamma; Ionomycin; Isoquinolines; Macrophage-1 Antigen; Macrophages; Piperazines; Protein Kinase C; Receptors, Complement; Receptors, Fc; Receptors, IgG; Signal Transduction; Tetradecanoylphorbol Acetate | 1990 |
Muscarinic receptor-mediated translocation of calmodulin in SK-N-SH human neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Biological Transport; Calcium; Calmodulin; Carbachol; Humans; Ionomycin; Isoquinolines; Kinetics; Neuroblastoma; Piperazines; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1990 |
Diacylglycerol and calcium induce rapid enhancement of A-system amino acid transport by independent mechanisms in human T-lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acids; Biological Transport; Calcium; Cycloheximide; Cytoplasm; Diglycerides; Egtazic Acid; Ethers; Extracellular Space; Glycerides; Humans; In Vitro Techniques; Ionomycin; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; T-Lymphocytes | 1989 |
Induction of high-affinity interleukin 2 receptors on human T lymphocytes. The role of calcium and protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Diglycerides; Egtazic Acid; Ethers; Humans; Interleukin-2; Ionomycin; Isoquinolines; Phytohemagglutinins; Piperazines; Protein Kinase C; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Activation signals in human lymphocytes. Incorporation of polyunsaturated fatty acids into plasma membrane phospholipids regulates IL-2 synthesis via sustained activation of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cells, Cultured; Diglycerides; DNA; Fatty Acids, Unsaturated; Humans; In Vitro Techniques; Indomethacin; Interleukin-2; Ionomycin; Isoquinolines; Linoleic Acid; Linoleic Acids; Lymphocyte Activation; Lymphocytes; Masoprocol; Membrane Lipids; Phospholipids; Piperazines; Protein Kinase C; Receptors, Antigen, T-Cell; Sphingosine | 1989 |
Phorbol diesters and dioctanoylglycerol stimulate accumulation of both diacylglycerols and alkylacylglycerols in human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Chlorpromazine; Diglycerides; Ethers; Glycerides; Glyceryl Ethers; Humans; In Vitro Techniques; Ionomycin; Isoquinolines; Kinetics; Neutrophils; Piperazines; Protein Kinase C; Sphingosine; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Effects of protein kinase C (PK-C) activators and inhibitors on human large granular lymphocytes (LGL): role of PK-C on natural killer (NK) activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Diglycerides; Enzyme Activation; Ethers; Humans; Immunity, Innate; Ionomycin; Isoquinolines; Killer Cells, Natural; Molecular Weight; Phosphoproteins; Piperazines; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate | 1989 |
Mechanism of cellular effect of phorbol esters on action of arginine vasopressin and angiotensin II on rat vascular smooth muscle cells in culture.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Arginine Vasopressin; Calcium; Cells, Cultured; Depression, Chemical; Ethers; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Isoquinolines; Muscle, Smooth, Vascular; Piperazines; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1988 |
Receptor-mediated activation of electropermeabilized neutrophils. Evidence for a Ca2+- and protein kinase C-independent signaling pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Cell Membrane Permeability; Diglycerides; Ethers; Flow Cytometry; Humans; Ionomycin; Isoquinolines; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Oxygen Consumption; Phorbol Esters; Piperazines; Protein Kinase C | 1988 |
Polyamine transport in human promyelocytic leukemia cells and polymorphonuclear leukocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Biological Transport; Cell Line; Genistein; Gramicidin; Humans; In Vitro Techniques; Ionomycin; Isoflavones; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Neutrophils; Piperazines; Protein Kinase Inhibitors; Putrescine; Spermidine; Spermine; Sulfonamides; Temperature; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Differential modulation by protein kinase C of progesterone-activated responses in human sperm.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Calcium; Cell Membrane; Fluorescent Dyes; Fura-2; Gramicidin; Humans; In Vitro Techniques; Ionomycin; Isoquinolines; Kinetics; Male; Membrane Potentials; Piperazines; Progesterone; Protein Kinase C; Spermatozoa; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Vasoactive intestinal polypeptide stimulates cyclic AMP production in mouse N1E-115 neuroblastoma cells: modulation by a protein kinase C activator and ionomycin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carcinogens; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Enzyme Activation; Ionomycin; Isoquinolines; Kinetics; Mice; Neuroblastoma; Phorbol Esters; Piperazines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1994 |
Mediation of pepsinogen secretion from guinea pig chief cells by Ca2+/calmodulin-dependent protein kinase II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Gastric Mucosa; Guinea Pigs; Immunohistochemistry; Ionomycin; Isoquinolines; Male; Pepsinogens; Phosphorylation; Piperazines | 1995 |
Nuclear calcium signaling is initiated by cytosolic calcium surges in vascular smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Angiotensin II; Animals; Calcium; Cell Nucleus; Cells, Cultured; Cytosol; Ionomycin; Isoquinolines; Kinetics; Microscopy, Confocal; Muscle, Smooth, Vascular; Piperazines; Potassium Chloride; Protein Kinase C; Rats; Second Messenger Systems; Signal Transduction; Staurosporine; Terpenes; Thapsigargin | 1994 |
Role of myosin light-chain kinase and protein kinase C in pepsinogen secretion from guinea pig gastric chief cells in monolayer culture.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Azepines; Calcium; Carbachol; Cells, Cultured; Colforsin; Gastric Mucosa; Guinea Pigs; Immunoenzyme Techniques; Ionomycin; Isoquinolines; Male; Microscopy, Electron; Myosin-Light-Chain Kinase; Pepsinogens; Piperazines; Protein Kinase C; Rabbits; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1994 |
Prostaglandin F2 alpha enhances tyrosine phosphorylation and DNA synthesis through phospholipase C-coupled receptor via Ca(2+)-dependent intracellular pathway in NIH-3T3 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Calcium; Dinoprost; DNA; Ionomycin; Isoquinolines; Mice; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Receptors, Prostaglandin; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Type C Phospholipases; Tyrosine | 1994 |
Differential involvement of phospholipase A2 in phorbol ester-induced luteinizing hormone and growth hormone release from rat anterior pituitary tissue.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminobenzoates; Animals; Arachidonic Acid; Aristolochic Acids; Chlorobenzoates; Cinnamates; Cyclohexanones; Cycloheximide; Enzyme Activation; Female; Growth Hormone; Indoles; Ionomycin; Isoquinolines; Luteinizing Hormone; Melitten; ortho-Aminobenzoates; Phenanthrenes; Phenothiazines; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Piperazines; Pituitary Gland, Anterior; Proestrus; Protein Kinase C; Quinacrine; Rats; Rats, Wistar; Signal Transduction; Staurosporine | 1993 |
The requirement of p47 phosphorylation for activation of NADPH oxidase by opsonized zymosan in human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blood Proteins; Cell Membrane; Cytosol; Enzyme Activation; Humans; Ionomycin; Isoquinolines; Kinetics; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phosphates; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Oestradiol-17 beta modulates the actions of pharmacologically distinct forms of protein kinase C in rat anterior pituitary cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cytosol; Diglycerides; Enzyme Activation; Estradiol; Female; Growth Hormone; Ionomycin; Isoenzymes; Isoquinolines; Luteinizing Hormone; Ovariectomy; Phorbol 12,13-Dibutyrate; Piperazines; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar | 1993 |
Signal-transduction mechanisms of ATP-stimulated phosphatidylcholine secretion in rat type II pneumocytes: interactions between ATP and other surfactant secretagogues.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Drug Interactions; Ionomycin; Isoquinolines; L-Lactate Dehydrogenase; Lung; Male; Phosphatidylcholines; Piperazines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides; Terbutaline; Tetradecanoylphorbol Acetate; Xanthines | 1993 |
Signaling pathways for antigen receptor-mediated induction of transcription factor CREB in B lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antibodies, Anti-Idiotypic; Antigens, CD; B-Lymphocytes; B7-2 Antigen; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Immunoglobulins; Ionomycin; Isoquinolines; Lymphoma, B-Cell; Membrane Glycoproteins; Mice; Molecular Sequence Data; Phosphorylation; Piperazines; Protein Kinase C; Rats; Receptors, Antigen, B-Cell; Signal Transduction; Staurosporine; Sulfonamides | 1996 |
Protein kinase C plays a key role in the cross-talk between intracellular signalings via prostanoid receptors in a megakaryoblastic cell line, MEG-01s.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Calcium; Cell Line; Cyclic AMP; Dinoprostone; Hematopoietic Stem Cells; Humans; Iloprost; Ionomycin; Megakaryocytes; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Prostaglandin; Receptors, Thrombin; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1996 |
Glucose stimulates islet beta-cell mitogenesis through GTP-binding proteins and by protein kinase C-dependent mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atrial Natriuretic Factor; Calcium Channel Blockers; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gallopamil; Glucose; GTP-Binding Proteins; Insulin; Insulin Secretion; Ionomycin; Ionophores; Islets of Langerhans; Pertussis Toxin; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1997 |
Calmodulin-dependent protein kinases mediate calcium-induced slow motility of mammalian outer hair cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Azepines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Hair Cells, Auditory, Outer; Ionomycin; Ionophores; Isoquinolines; Myosin-Light-Chain Kinase; Naphthalenes; Phosphorylation; Staurosporine; Sulfonamides | 1997 |
Assessment of the mechanism by which prolactin stimulates progesterone production by early corpora lutea of pigs.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carcinogens; Cells, Cultured; Corpus Luteum; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Female; Ionomycin; Ionophores; Lipoproteins, LDL; Luteal Phase; Phorbol 12,13-Dibutyrate; Progesterone; Prolactin; Protein Kinase C; Staurosporine; Stimulation, Chemical; Swine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1998 |
Xenon induces metaphase arrest in rat astrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anaphase; Anesthetics, Inhalation; Animals; Astrocytes; Brain; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromosome Segregation; Helium; Ionomycin; Isoflurane; Metaphase; Mitosis; Mitotic Index; Nitrogen; Rats; Time Factors; Xenon | 1999 |
Modulation of carbachol-stimulated AP-1 DNA binding activity by therapeutic agents for bipolar disorder in human neuroblastoma SH-SY5Y cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antipsychotic Agents; Bipolar Disorder; Calcium; Calcium Signaling; Carbachol; Carbamazepine; Chelating Agents; DNA; Dose-Response Relationship, Drug; Edetic Acid; Egtazic Acid; Gene Expression Regulation; Humans; Indoles; Ionomycin; Ionophores; Lithium; Muscarinic Agonists; Nerve Tissue Proteins; Neuroblastoma; Neurons; Phosphatidylinositols; Protein Binding; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured; Valproic Acid | 1999 |
Regulation of LPA-promoted myofibroblast contraction: role of Rho, myosin light chain kinase, and myosin light chain phosphatase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; ADP Ribose Transferases; Alkaloids; Azepines; Botulinum Toxins; Calcimycin; Calcium; Carbazoles; Cells, Cultured; Enzyme Inhibitors; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Ionomycin; Kinetics; Lysophospholipids; Models, Chemical; Muscle Contraction; Muscle, Skeletal; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Naphthalenes; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Recombinant Proteins; rho-Associated Kinases | 2000 |
Ca2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Calcimycin; Calcineurin; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation; Heart; Ionomycin; Kinetics; Models, Cardiovascular; Myocardium; Myosin Heavy Chains; Promoter Regions, Genetic; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Components of the intracellular cAMP system supporting the olfactory reception of amyl alcohol.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Aluminum Compounds; Animals; Antimetabolites; Caffeine; Calcium Channel Blockers; Calcium Chloride; Chelating Agents; Chlortetracycline; Colforsin; Cyclic AMP; Dideoxyadenosine; Egtazic Acid; Fluorides; In Vitro Techniques; Ionomycin; Ionophores; Microscopy, Fluorescence; Nifedipine; Olfactory Mucosa; Pentanols; Phosphodiesterase Inhibitors; Rana temporaria; Reaction Time; Signal Transduction; Smell | 2003 |
Regulation of CO production in cerebral microvessels of newborn pigs.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aminolevulinic Acid; Animals; Animals, Newborn; Calcium; Calcium Signaling; Capillaries; Carbon Monoxide; Catalysis; Cerebrovascular Circulation; Cytosol; Enzyme Inhibitors; Genistein; Heme; Heme Oxygenase (Decyclizing); In Vitro Techniques; Ionomycin; Ionophores; Phosphorylation; Photosensitizing Agents; Swine; Tetradecanoylphorbol Acetate; Tyrphostins; Vanadates | 2003 |
Insulin-stimulated cyclic guanosine monophosphate inhibits vascular smooth muscle cell migration by inhibiting Ca/calmodulin-dependent protein kinase II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Insulin; Ionomycin; Male; Muscle, Smooth, Vascular; Mutation; Phosphorylation; Rats; Rats, Sprague-Dawley; Threonine | 2003 |
Calcium signalling in the regulation of PGC-1alpha, PDK4 and HKII mRNA expression.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Caffeine; Calcium Signaling; Cells, Cultured; Cyclosporine; Electric Stimulation; Gene Expression Regulation; Hexokinase; Ionomycin; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Kinases; Rats; Rats, Wistar; RNA-Binding Proteins; RNA, Messenger; Transcription Factors | 2007 |
Osthole or imperatorin-mediated facilitation of glutamate release is associated with a synaptic vesicle mobilization in rat hippocampal glutamatergic nerve endings.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Central Nervous System Agents; Coumarins; Cytochalasin D; Enzyme Inhibitors; Furocoumarins; Glutamic Acid; Hippocampus; Ionomycin; Male; Neurons; Potassium Chloride; Rats; Rats, Sprague-Dawley; Synapsins; Synaptic Vesicles | 2010 |