Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and sphingosine 1-phosphate

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with sphingosine 1-phosphate in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hakomori, S; Igarashi, Y; Mazurek, N; Megidish, T1
Hashizume, T; Nakao, M; Sato, T1
Harvey, KA; Paranavitana, CN; Siddiqui, RA; Zaloga, GP1
Kaneko, S; Okamoto, Y; Sugimoto, N; Takamura, M; Takashima, S; Takata, S; Takuwa, N; Takuwa, Y; Yoshioka, K1
Adachi, S; Hanai, Y; Kozawa, O; Matsushima-Nishiwaki, R; Minamitani, C; Mizutani, J; Otsuka, T; Takai, S; Tokuda, H1
Balogh, A; Benyó, Z; Dancs, PT; Fülöp, Á; Kerék, M; Móré, D; Offermanns, S; Panta, CR; Proia, RL; Ruisanchez, É; Tigyi, GJ1

Other Studies

6 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and sphingosine 1-phosphate

ArticleYear
Regulatory effect of phorbol esters on sphingosine kinase in BALB/C 3T3 fibroblasts (variant A31): demonstration of cell type-specific response--a preliminary note.
    Biochemical and biophysical research communications, 1994, Jan-14, Volume: 198, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Isoenzymes; Isoquinolines; Kinetics; Lysophospholipids; Mice; Mice, Inbred BALB C; Phosphotransferases (Alcohol Group Acceptor); Piperazines; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate

1994
Sphingosine enhances phosphatidylinositol 4-kinase activity in rabbit platelets.
    Journal of biochemistry, 1996, Volume: 120, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Phosphatidylinositol 4-Kinase; Androstadienes; Animals; Arachidonic Acid; Blood Platelets; Ceramides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Lysophospholipids; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Rabbits; Sphingosine; Staurosporine; Wortmannin

1996
Diverse signaling pathways regulate fibroblast differentiation and transformation through Rho kinase activation.
    Journal of cellular physiology, 2007, Volume: 211, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Cell Differentiation; Cell Line; Cell Lineage; Cell Shape; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Activation; Fibroblasts; Humans; Intracellular Signaling Peptides and Proteins; Laminin; Lung; Lysophospholipids; Morphogenesis; Phenotype; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proteoglycans; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Time Factors; Transfection; Transforming Growth Factor beta1

2007
G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.
    Cardiovascular research, 2008, Sep-01, Volume: 79, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; ADP Ribose Transferases; Animals; Botulinum Toxins; Calcium; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gq-G11; Lysophospholipids; Male; Muscle, Smooth, Vascular; Protein Kinase C; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pyrazoles; Pyridines; rac GTP-Binding Proteins; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Lysosphingolipid; Recombinant Fusion Proteins; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Sphingosine; Transfection

2008
Involvement of Rho-kinase in sphingosine 1-phosphate-stimulated HSP27 induction in osteoblasts.
    International journal of molecular medicine, 2009, Volume: 24, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cell Line; HSP27 Heat-Shock Proteins; Lysophospholipids; Mice; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; rho-Associated Kinases; Sphingosine

2009
Sphingosine-1-Phosphate Enhances α
    International journal of molecular sciences, 2019, Dec-17, Volume: 20, Issue:24

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Drug Synergism; Lysophospholipids; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Pyridines; Receptors, Adrenergic, alpha-1; rho-Associated Kinases; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

2019