1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with sirolimus in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kahan, BD; Kerman, RH; Kimball, P; Williams, J | 1 |
| Frank, DA; Huo, L; Karras, JG; Rothstein, TL; Wang, Z; Zimmet, JM | 1 |
| Adachi, M; Imai, K; Minami, Y; Miyazaki, T; Reed, JC; Sekiya, M; Takayama, S; Taniguchi, T; Torigoe, T | 1 |
| Frank, DA; Howard, RG; Huo, L; Karras, JG; Rothstein, TL; Wang, Z | 1 |
| Berti, L; Capp, E; Häring, HU; Kellerer, M | 1 |
| Caivano, M; Cohen, P; Davies, SP; Reddy, H | 1 |
| Honma, Y; Kasukabe, T; Okabe-Kado, J; Yamamoto-Yamaguchi, Y | 1 |
| Acitores, A; González, N; Sancho, V; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Hu, H; Li, F; Liu, F; Ma, W; Pan, Q; Ran, C; Wang, J; Yang, Q | 1 |
9 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and sirolimus
| Article | Year |
|---|---|
Cyclosporine and rapamycin block protein kinase C-mediated induction of the activation signal, activator of DNA replication, in cell-free assay.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell-Free System; Cyclosporine; DNA Replication; Enzyme Induction; Humans; Immunosuppressive Agents; Isoquinolines; Lymphocyte Activation; Lymphocytes; Piperazines; Polyenes; Protein Kinase C; Sirolimus | 1993 |
Delayed tyrosine phosphorylation and nuclear expression of STAT1 following antigen receptor stimulation of B lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Cell Nucleus; DNA-Binding Proteins; Down-Regulation; Interferon Regulatory Factor-1; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Nucleoproteins; Phosphoproteins; Phosphorylation; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Receptors, Antigen, B-Cell; Sirolimus; STAT1 Transcription Factor; Trans-Activators; Transcription Factors; Tyrosine | 1996 |
Interleukin-2 (IL-2) upregulates BAG-1 gene expression through serine-rich region within IL-2 receptor beta c chain.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Carrier Proteins; Cell Line; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation; Genistein; Hematopoietic Stem Cells; Humans; Interleukin-2; Isoflavones; Janus Kinase 3; Lymphocytes; Mice; Phosphorylation; Phytohemagglutinins; Polyenes; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-bcl-2; Receptors, Interleukin-2; RNA, Messenger; Serine; Signal Transduction; Sirolimus; Stimulation, Chemical; Tacrolimus; Transcription Factors; Transfection | 1996 |
Signal transducer and activator of transcription-3 (STAT3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acute-Phase Proteins; Animals; B-Lymphocyte Subsets; B-Lymphocytes; CD5 Antigens; Cell Nucleus; Cells, Cultured; Dimerization; DNA-Binding Proteins; Genes, fos; Humans; Immunosuppressive Agents; Interleukin-6; Kinetics; Male; Mice; Mice, Inbred BALB C; Oligodeoxyribonucleotides; Polyenes; Protein Kinase Inhibitors; Signal Transduction; Sirolimus; Spleen; STAT3 Transcription Factor; Trans-Activators | 1997 |
Leptin stimulates glucose transport and glycogen synthesis in C2C12 myotubes: evidence for a P13-kinase mediated effect.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Androstadienes; Animals; Biological Transport; Cell Line; Deoxyglucose; Enzyme Inhibitors; Glucose; Glycogen; Insulin; Kinetics; Leptin; Muscle Fibers, Skeletal; Obesity; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Polyenes; Proteins; Rats; Sirolimus; Wortmannin | 1997 |
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides | 2000 |
Induction of differentiation of human myeloid leukemia cells by immunosuppressant macrolides (rapamycin and FK506) and calcium/calmodulin-dependent kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Enzyme Inhibitors; HL-60 Cells; Humans; Immunophilins; Immunosuppressive Agents; K562 Cells; Leukemia, Myeloid; Neoplasm Proteins; Protein Serine-Threonine Kinases; Sirolimus; Sulfonamides; Tacrolimus; Tacrolimus Binding Proteins; Tumor Cells, Cultured; U937 Cells | 2001 |
Effect of GLP-1 on glucose transport and its cell signalling in human myocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Aged, 80 and over; Androstadienes; Biological Transport; Cells, Cultured; Enzyme Activation; Exenatide; Female; Flavonoids; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Indoles; Insulin; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Cells; Peptide Fragments; Peptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Precursors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Venoms; Wortmannin | 2005 |
A Novel Rabbit Model for Benign Biliary Stricture Formation and the Effects of Medication Infusions on Stricture Formation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antineoplastic Agents; Biliary Tract Diseases; Constriction, Pathologic; Disease Models, Animal; Drug Evaluation, Preclinical; Pyridones; Rabbits; Secondary Prevention; Sirolimus; Vasodilator Agents | 2018 |