1-(5-isoquinolinesulfonyl)-2-methylpiperazine and sb 203580

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with sb 203580 in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's9 (69.23)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hammermann, R; Häussinger, D; Warskulat, U1
Caivano, M; Cohen, P; Davies, SP; Reddy, H1
Choi, MR; Suh, HW; Won, JS1
Gimbrone, MA; Masuda, J; Ochi, H1
Engström, U; Grimsby, S; Heldin, CH; Souchelnytskyi, S; Yakymovych, I1
Blanquet, PR; Derer, P; Mariani, J1
Hanada, K; Kageyama, K; Suda, T1
Bai, XD; Fu, XB; Sun, TZ; Zhang, Q1
Horie, K; Ohashi, M; Sairenji, T; Satoh, Y1
Clay, WC; Condreay, JP; Hall, M; Holbrook, J; Livermore, D; Michel, AD; Ng, SW; Roman, S; Senger, S; Thompson, K1
Chatterjee, S; Dua, R; Jailkhani, N; Jamal, MS; Rao, KV; Ravichandran, S1
Andrews, MA; Austin, M; Ibe, BO; Lazaro, M; Lustina, J; Raj, JU; Renteria, LS1
Liu, Y; Rao, P; Sang, Y; Shang, F; Wen, J; Xu, F; Xu, Y; Zhu, L1

Other Studies

13 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and sb 203580

ArticleYear
Anisoosmotic regulation of the Nopp140 mRNA in H4IIE rat hepatoma cells and primary hepatocytes.
    FEBS letters, 1999, Jun-11, Volume: 452, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleolus; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Hypertonic Solutions; Imidazoles; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Transcription, Genetic; Water-Electrolyte Balance

1999
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
    The Biochemical journal, 2000, Oct-01, Volume: 351, Issue:Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides

2000
Stimulation of astrocyte-enriched culture with C2 ceramide increases proenkephalin mRNA: involvement of cAMP-response element binding protein and mitogen activated protein kinases.
    Brain research, 2001, Jun-08, Volume: 903, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Astrocytes; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Enkephalins; Enzyme Inhibitors; Flavonoids; Gene Expression; Imidazoles; Isoquinolines; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Protein Precursors; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sphingosine; Stimulation, Chemical; Sulfonamides; Transcription Factor AP-1

2001
Hyperosmotic stimuli inhibit VCAM-1 expression in cultured endothelial cells via effects on interferon regulatory factor-1 expression and activity.
    European journal of immunology, 2002, Volume: 32, Issue:7

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Membrane; Cells, Cultured; Culture Media; Cycloheximide; DNA-Binding Proteins; E-Selectin; Endothelium, Vascular; Gene Expression Regulation; GTP-Binding Proteins; Imidazoles; Intercellular Adhesion Molecule-1; Interferon Regulatory Factor-1; Interferon-gamma; Interferon-Stimulated Gene Factor 3; Interleukin-1; Interleukin-13; Interleukin-4; NF-kappa B; Okadaic Acid; Osmosis; Phosphoproteins; Promoter Regions, Genetic; Pyridines; RNA, Messenger; Staurosporine; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2002
Inhibition of transforming growth factor-beta signaling by low molecular weight compounds interfering with ATP- or substrate-binding sites of the TGF beta type I receptor kinase.
    Biochemistry, 2002, Sep-10, Volume: 41, Issue:36

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amino Acid Sequence; Animals; Antennapedia Homeodomain Protein; Binding Sites; Cell Line; COS Cells; DNA-Binding Proteins; Enzyme Inhibitors; Homeodomain Proteins; Imidazoles; Mink; Molecular Mimicry; Molecular Sequence Data; Molecular Weight; Nuclear Proteins; Peptide Fragments; Protein Serine-Threonine Kinases; Pyridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Signal Transduction; Smad2 Protein; Smad3 Protein; Substrate Specificity; Trans-Activators; Transcription Factors; Transforming Growth Factor beta

2002
A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus.
    Neuroscience, 2003, Volume: 118, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Androstadienes; Animals; Antibodies; Benzophenanthridines; Benzopyrans; Blotting, Western; Brain-Derived Neurotrophic Factor; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbazoles; Cell Nucleus; Chromones; Cyclic AMP Response Element-Binding Protein; Cytosol; Enzyme Inhibitors; Flavonoids; Hippocampus; Imidazoles; Immunohistochemistry; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Male; Morpholines; Naphthalenes; Phenanthridines; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rats; Signal Transduction; Time Factors; Tyrphostins; Wortmannin

2003
Regulation of corticotropin-releasing factor receptor type 2beta mRNA by mitogen-activated protein kinases in aortic smooth muscle cells.
    Regulatory peptides, 2005, Mar-30, Volume: 126, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anisomycin; Aorta; Cell Line; Corticotropin-Releasing Hormone; Down-Regulation; Flavonoids; Gene Expression Regulation; Imidazoles; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Receptors, Corticotropin-Releasing Hormone; Ribonucleases; Up-Regulation; Urocortins

2005
[Mechanism of signal transduction of differentiation of mesenchymal stem cells into cytokeratin-expressing epidermoid cells].
    Zhonghua yi xue za zhi, 2006, May-16, Volume: 86, Issue:18

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Epidermal Cells; Epidermal Growth Factor; Epidermis; Female; Flavonoids; Flow Cytometry; Hyaluronan Receptors; Imidazoles; Immunohistochemistry; Integrin beta1; Keratin-19; Keratins; Male; Mechanotransduction, Cellular; Mesenchymal Stem Cells; Pyridines; Rats; Rats, Wistar; Time Factors

2006
The role of p38 mitogen-activated protein kinase in regulating interleukin-10 gene expression in Burkitt's lymphoma cell lines.
    Microbiology and immunology, 2007, Volume: 51, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Burkitt Lymphoma; Cell Line; Enzyme Inhibitors; Gene Expression; Humans; Imidazoles; Interleukin-10; Janus Kinase 1; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptors, Interleukin-10; RNA, Messenger; TYK2 Kinase

2007
Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects.
    British journal of pharmacology, 2008, Volume: 155, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Cell Line; Cloning, Molecular; Dose-Response Relationship, Drug; Glycine; Humans; Imidazoles; Molecular Sequence Data; Mutagenesis, Site-Directed; Piperazines; Plasmids; Polymorphism, Single Nucleotide; Protein Binding; Protein Structure, Tertiary; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridines; Pyridoxal Phosphate; Radioligand Assay; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Sequence Alignment; Species Specificity; Transfection

2008
Defining the antigen receptor-dependent regulatory network that induces arrest of cycling immature B-lymphocytes.
    BMC systems biology, 2010, Dec-09, Volume: 4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; B-Lymphocytes; Cell Cycle; Cell Line, Tumor; Feedback, Physiological; Gene Expression Profiling; Imidazoles; Mice; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptors, Antigen, B-Cell; Signal Transduction; src-Family Kinases; Systems Biology; Transcription Factors

2010
RhoA-Rho kinase and platelet-activating factor stimulation of ovine foetal pulmonary vascular smooth muscle cell proliferation.
    Cell proliferation, 2013, Volume: 46, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Flavonoids; Imidazoles; Lung; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Mutation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; rho-Associated Kinases; rhoA GTP-Binding Protein; Sheep

2013
Fasudil inhibits LPS-induced migration of retinal microglial cells via regulating p38-MAPK signaling pathway.
    Molecular vision, 2016, Volume: 22

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Blotting, Western; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Imidazoles; Lipopolysaccharides; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Microglia; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Retinal Neurons; Signal Transduction

2016