1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with prazosin in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cragoe, EJ; Hori, M; Iwakura, K; Kamada, T; Kitabatake, A; Watanabe, Y; Yoshida, H | 1 |
| Cragoe, EJ; Hara, M; Inagaki, C; Inoue, M; Omori, K; Otani, H; Uriu, T | 1 |
| Endoh, M; Kasai, H; Norota, I; Takanashi, M | 1 |
| Büscher, R; Grübbel, B; Insel, PA; Michel, MC; Taguchi, K; Yang, M | 1 |
| Burnstock, G; Smith, NC | 1 |
| Brock, JA; Yeoh, M | 1 |
| Hirano, Y; Hiraoka, M; Lin, J; Zhang, S | 1 |
| Beil, M; Danhof, M; Fu, F; Luttringer, O; Ploeger, BA; Rigel, DF; Snelder, N; Stanski, DR | 1 |
8 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and prazosin
| Article | Year |
|---|---|
Alpha 1-adrenoceptor stimulation increases intracellular pH and Ca2+ in cardiomyocytes through Na+/H+ and Na+/Ca2+ exchange.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-Agonists; Amiloride; Animals; Calcium; Fluorescent Dyes; Heart; Hydrogen; Hydrogen-Ion Concentration; Ion Exchange; Isoquinolines; Male; Myocardium; Norepinephrine; Phentolamine; Piperazines; Prazosin; Propranolol; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Sodium; Yohimbine | 1990 |
Effects of inhibitors of protein kinase C and Na+/H+ exchange on alpha 1-adrenoceptor-mediated inotropic responses in the rat left ventricular papillary muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amiloride; Animals; Heart Ventricles; Hydrogen; In Vitro Techniques; Ion Exchange; Isoquinolines; Male; Myocardial Contraction; Papillary Muscles; Piperazines; Prazosin; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sodium; Staurosporine | 1990 |
Inotropic effects of staurosporine, NA 0345 and H-7, protein kinase C inhibitors, on rabbit ventricular myocardium: selective inhibition of the positive inotropic effect mediated by alpha 1-adrenoceptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Carbazoles; Heart Ventricles; Hydrolysis; Indoles; Isoquinolines; Male; Myocardial Contraction; Myocardium; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Piperazines; Prazosin; Protein Kinase C; Rabbits; Receptors, Adrenergic, alpha; Staurosporine | 1993 |
Protein kinase C does not mediate phenylephrine-induced down-regulation of Madin-Darby canine kidney cell alpha-1B adrenoceptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; beta-Adrenergic Receptor Kinases; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dogs; Down-Regulation; G-Protein-Coupled Receptor Kinase 3; Indomethacin; Phenylephrine; Prazosin; Protein Kinase C; Protein Serine-Threonine Kinases; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate | 1998 |
Mechanisms underlying postjunctional synergism between responses of the vas deferens to noradrenaline and ATP.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Cantharidin; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Histamine; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle, Smooth; Naphthalenes; Norepinephrine; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Prazosin; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; rho-Associated Kinases; Vas Deferens | 2004 |
Rho kinase inhibitors reduce neurally evoked contraction of the rat tail artery in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Amides; Animals; Arteries; Clonidine; Electric Stimulation; Electrophysiology; Female; Idazoxan; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Phenylephrine; Prazosin; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Purinergic P2 Receptor Antagonists; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Suramin; Tail; Vasoconstriction | 2005 |
Modulation of ICa-L by alpha1-adrenergic stimulation in rat ventricular myocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Calcium; Calcium Channels, L-Type; Enzyme Inhibitors; Heart Ventricles; Inositol 1,4,5-Trisphosphate; Methoxamine; Muscle Cells; Phenylephrine; Prazosin; Propranolol; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Ventricular Function | 2005 |
Drug effects on the CVS in conscious rats: separating cardiac output into heart rate and stroke volume using PKPD modelling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Amlodipine; Animals; Atropine; Enalapril; Hemodynamics; Hydrochlorothiazide; Hypertension; Male; Models, Biological; Prazosin; Propranolol; Rats, Inbred SHR; Rats, Inbred WKY | 2014 |