Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and phorbol-12,13-didecanoate

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with phorbol-12,13-didecanoate in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (12.50)	18.7374
1990's	20 (83.33)	18.2507
2000's	1 (4.17)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Emoto, S; Ichikawa, A; Imanishi, N; Kawai, H; Ohgoh, M; Ohmori, E; Yatsunami, K	1
Hata, K; Kukita, A; Kukita, T; Kurisu, K	1
Obara, K; Usuki, T; Yabu, H	1
Endo, Y; Furuya, S; Matsui, Y; Nozawa, S; Oba, M; Suzuki, S	1
Endo, Y; Furuya, S; Nozawa, S; Oba, M; Suzuki, S	1
Friesel, RE; Peifley, KA; Winkles, JA	1
Byrne, JH; Critz, SD	1
Gupta, A; Renfro, JL	1
Mattson, MP	1
Crane, DL; Elliott, MS	1
Fredholm, B; Gullberg, M; Jondal, M; Kvanta, A; Nordstedt, C	1
Cline, HT; Constantine-Paton, M	1
Kuroki, T; Nose, K; Shibanuma, M	1
Craven, PA; DeRubertis, FR; Patterson, MC	1
Carroll, AG; Eckberg, WR; Szuts, EZ	1
Betz, H; Sato, K; Schloss, P	1
de Prost, D; Hakim, J; Khechai, F; Ollivier, V; Ramani, M; Ternisien, C; Vu, T	1
Chik, CL; Ho, AK; Inukai, T	1
Fujii, N; Matsumoto, A; Nomizu, M; Okusu, A; Otaka, A; Tamamura, H; Weeks, BS; Weston, CA; Yamamoto, N	1
Busija, D; Nam, M; Thore, CR	1
Dahmer, MK; Penberthy, WT	1
Black, SC; Chi, L; Fagbemi, SO; Friedrichs, GS; Lucchesi, BR	1
Bavister, BD; Rose-Hellekant, TA	1
Chung, KH; Gye, MH; Shin, HJ; Yoo, BS	1

Other Studies

24 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and phorbol-12,13-didecanoate

Article	Year
Synergistic effects of 12-O-tetradecanoylphorbol-13-acetate and dexamethasone on de novo synthesis of histidine decarboxylase in mouse mastocytoma P-815 cells. Biochimica et biophysica acta, 1992, Jan-13, Volume: 1133, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carcinogens; Dexamethasone; Diglycerides; Drug Synergism; Enzyme Activation; Ethers, Cyclic; Histidine Decarboxylase; Isoquinolines; Mast-Cell Sarcoma; Mice; Okadaic Acid; Phorbol Esters; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured	1992
12-O-tetradecanoylphorbol-13-acetate inhibits osteoclast-like cell differentiation in rat bone marrow cultures by inducing macrophage polykaryons. Endocrinology, 1992, Volume: 130, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acid Phosphatase; Animals; Biomarkers; Bone Marrow; Bone Marrow Cells; Bone Resorption; Calcitonin; Calcitriol; Carcinogens; Cell Differentiation; Cells, Cultured; Isoquinolines; Kinetics; Macrophages; Microscopy, Electron, Scanning; Models, Biological; Osteoclasts; Phorbol Esters; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Calcitonin; Receptors, Cell Surface; Tetradecanoylphorbol Acetate	1992
Calcium and potassium channel regulation by protein phosphorylation in smooth muscle cells of guinea pig taenia coli. Advances in experimental medicine and biology, 1992, Volume: 311 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Atropine; Calcium Channels; Carbachol; Colon; Guinea Pigs; In Vitro Techniques; Isoquinolines; Marine Toxins; Membrane Potentials; Models, Biological; Muscle, Smooth; Nifedipine; Oxazoles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Piperazines; Potassium Channels; Protein Kinase C	1992
Protein phosphorylation regulates the mouse sperm acrosome reaction induced by the zona pellucida. Journal of assisted reproduction and genetics, 1992, Volume: 9, Issue:4 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acrosome; Alkaloids; Animals; Diglycerides; Ethers, Cyclic; Exocytosis; Female; Genistein; Isoflavones; Isoquinolines; Male; Membrane Fusion; Mice; Okadaic Acid; Phorbol Esters; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Signal Transduction; Sperm-Ovum Interactions; Staurosporine; Tetradecanoylphorbol Acetate; Zona Pellucida	1992
Effects of modulators of protein kinases and phosphatases on mouse sperm capacitation. Journal of assisted reproduction and genetics, 1992, Volume: 9, Issue:4 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bucladesine; Chlortetracycline; Dibutyryl Cyclic GMP; Diglycerides; Ethers, Cyclic; Fluorescence; Genistein; Isoflavones; Isoquinolines; Male; Mice; Okadaic Acid; Peptide Fragments; Phorbol Esters; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Sperm Capacitation; Staurosporine; Tetradecanoylphorbol Acetate	1992
Tumor promoters induce basic fibroblast growth factor gene expression in human dermal fibroblasts. Cancer research, 1992, Feb-15, Volume: 52, Issue:4 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinogens; Cell Line; Diterpenes; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Fibroblasts; Gene Expression; Isoquinolines; Phorbol Esters; Piperazines; RNA, Messenger; Skin; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate	1992
Modulation of IK,Ca by phorbol ester-mediated activation of PKC in pleural sensory neurons of Aplysia. Journal of neurophysiology, 1992, Volume: 68, Issue:4 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aplysia; Calcium; Dose-Response Relationship, Drug; Enzyme Activation; Ganglia; In Vitro Techniques; Isoquinolines; Kinetics; Membrane Potentials; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Piperazines; Potassium Channels; Protein Kinase C; Protein Kinase Inhibitors; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetraethylammonium Compounds	1992
Effects of pH on phosphate transport by flounder renal tubule primary cultures. The American journal of physiology, 1991, Volume: 260, Issue:4 Pt 2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Absorption; Amiloride; Animals; Biological Transport; Cells, Cultured; Flounder; Hydrogen-Ion Concentration; Isoquinolines; Kidney Tubules; Kinetics; Phorbol Esters; Phosphates; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Sodium-Potassium-Exchanging ATPase; Type C Phospholipases	1991
Evidence for the involvement of protein kinase C in neurodegenerative changes in cultured human cortical neurons. Experimental neurology, 1991, Volume: 112, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Survival; Cells, Cultured; Cerebral Cortex; Fetus; Humans; Isoquinolines; Kinetics; Nerve Degeneration; Neurons; Phorbol Esters; Piperazines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate	1991
Protein kinase C modulation of queuine uptake in cultured human fibroblasts. Biochemical and biophysical research communications, 1990, Aug-31, Volume: 171, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Calcimycin; Cells, Cultured; Diglycerides; Enzyme Activation; Fibroblasts; Growth Substances; Guanine; Humans; In Vitro Techniques; Isoquinolines; Male; Phorbol Esters; Phosphatidylserines; Piperazines; Protein Kinase C; Sphingosine; Staurosporine	1990
Evidence that protein kinase C activation is essential for killing by IL-2-activated lymphocytes. Scandinavian journal of immunology, 1990, Volume: 31, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Chromium Radioisotopes; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Interleukin-2; Isoquinolines; Killer Cells, Lymphokine-Activated; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Piperazines; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured	1990
The differential influence of protein kinase inhibitors on retinal arbor morphology and eye-specific stripes in the frog retinotectal system. Neuron, 1990, Volume: 4, Issue:6 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Axons; Horseradish Peroxidase; Isoquinolines; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Piperazines; Polyvinyls; Protein Kinase Inhibitors; Rana pipiens; Retina; Retinal Ganglion Cells; Sphingosine; Superior Colliculi; Visual Pathways	1990
Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport. European journal of biochemistry, 1987, Apr-01, Volume: 164, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Amiloride; Aminopyridines; Biological Transport, Active; Calcimycin; Humans; Isoquinolines; Phorbol Esters; Piperazines; Potassium; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogenes; Quinidine; RNA, Messenger; Sodium; Tetraethylammonium Compounds; Transcription, Genetic	1987
Role for protein kinase C in the modulation of glomerular PGE2 production by angiotensin II. Biochemical and biophysical research communications, 1988, May-16, Volume: 152, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Dinoprostone; Female; Isoquinolines; Kidney Glomerulus; Phorbol Esters; Phorbols; Piperazines; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate	1988
Protein kinase C activity, protein phosphorylation and germinal vesicle breakdown in Spisula oocytes. Developmental biology, 1987, Volume: 124, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bivalvia; Fertilization; Isoquinolines; Oocytes; Phorbol Esters; Phosphoproteins; Phosphorylation; Piperazines; Potassium; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate; Vitamin A	1987
The recombinant GABA transporter GAT1 is downregulated upon activation of protein kinase C. FEBS letters, 1995, Nov-13, Volume: 375, Issue:1-2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Biological Transport; Carrier Proteins; Cell Line; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; Isoquinolines; Kidney; Kinetics; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters; Phorbol Esters; Piperazines; Protein Kinase C; Rats; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection	1995
Endotoxin-induced tissue factor in human monocytes is dependent upon protein kinase C activation. Thrombosis and haemostasis, 1993, Nov-15, Volume: 70, Issue:5 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Endotoxins; Enzyme Activation; Gene Expression Regulation; Humans; Isoquinolines; Monocytes; Naphthalenes; Naphthol AS D Esterase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Polycyclic Compounds; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thromboplastin	1993
Vasoactive intestinal polypeptide stimulates cyclic AMP production in mouse N1E-115 neuroblastoma cells: modulation by a protein kinase C activator and ionomycin. Peptides, 1994, Volume: 15, Issue:8 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carcinogens; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Enzyme Activation; Ionomycin; Isoquinolines; Kinetics; Mice; Neuroblastoma; Phorbol Esters; Piperazines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide	1994
Lymphocytes and promonocytes attach to the synthetic [Tyr5,12, Lys7]- polyphemusin II peptide. Biochemical and biophysical research communications, 1994, Jul-15, Volume: 202, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Antimicrobial Cationic Peptides; Cell Adhesion; Cell Line; HIV-1; Humans; Isoquinolines; Kinetics; Lymphocytes; Molecular Sequence Data; Monocytes; Peptides; Phorbol Esters; Piperazines; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Replication	1994
Phorbol ester-induced prostaglandin production in piglet cortical astroglia. The American journal of physiology, 1994, Volume: 267, Issue:1 Pt 2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Astrocytes; Cerebral Cortex; Dinoprost; Isoquinolines; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Prostaglandin Antagonists; Prostaglandins; Protein Kinase Inhibitors; Swine	1994
Insulin-like growth factor-I-enhanced secretion is abolished in protein kinase C-deficient chromaffin cells. Journal of neurochemistry, 1994, Volume: 62, Issue:5 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenal Medulla; Amino Acid Sequence; Analysis of Variance; Animals; Brain; Calcium; Catecholamines; Cattle; Cells, Cultured; Insulin-Like Growth Factor I; Isoquinolines; Kinetics; Molecular Sequence Data; Peptide Fragments; Phorbol Esters; Piperazines; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Rats; Substrate Specificity; Sulfonamides; Tetradecanoylphorbol Acetate	1994
Phorbol ester-induced ventricular fibrillation in the Langendorff-perfused rabbit heart: antagonism by staurosporine and glibenclamide. Journal of molecular and cellular cardiology, 1993, Volume: 25, Issue:12 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Diglycerides; Glyburide; Guanidines; Isoquinolines; Perfusion; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pinacidil; Piperazines; Protein Kinase C; Rabbits; Staurosporine; Ventricular Fibrillation	1993
Precocious oocyte maturation is induced by an inhibitor of cAMP-dependent protein kinase in the intact golden hamster. Molecular reproduction and development, 1996, Volume: 44, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Female; Indoles; Isoquinolines; Maleimides; Mesocricetus; Oocytes; Phorbol Esters; Protein Kinase C; Signal Transduction; Sulfonamides	1996
Activity of protein kinase C modulates the apoptosis induced by polychlorinated biphenyls in human leukemic HL-60 cells. Toxicology letters, 2002, Sep-05, Volume: 135, Issue:1-2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Chlorodiphenyl (54% Chlorine); Diglycerides; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Inhibitors; HL-60 Cells; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate	2002