1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with omega-n-methylarginine in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Day, RW; Ignarro, LJ; Klitzner, TS; Lai, WW | 1 |
| Craven, PA; DeRubertis, FR; Studer, RK | 1 |
| Fischer, T; Mohaupt, MG; Schulze-Lohoff, E; Schwöbel, J; Sterzel, RB | 1 |
| Chayama, K; Goto, C; Hara, K; Higashi, Y; Jitsuiki, D; Kimura, M; Nakagawa, K; Noma, K; Oshima, T; Yoshizumi, M | 1 |
| Chayama, K; Goto, C; Hara, K; Higashi, Y; Jitsuiki, D; Kimura, M; Nakagawa, K; Nishioka, K; Noma, K; Oshima, T; Umemura, T; Yoshizumi, M | 1 |
| Büssemaker, E; Herbrig, K; Palm, C; Passauer, J; Pistrosch, F | 1 |
| Andersson, DC; Fedotovskaya, O; Gonon, AT; Kiss, A; Lanner, JT; Pernow, J; Tratsiakovich, Y; Yang, J | 1 |
| Gonon, AT; Kiss, A; Pernow, J; Sjöquist, PO; Tratsiakovich, Y; Yang, J | 1 |
1 trial(s) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and omega-n-methylarginine
| Article | Year |
|---|---|
Smoking activates rho-kinase in smooth muscle cells of forearm vasculature in humans.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adolescent; Adult; Blood Pressure; Enzyme Inhibitors; Forearm; Humans; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Protein Serine-Threonine Kinases; Regional Blood Flow; rho-Associated Kinases; Smoking; Vasodilator Agents | 2003 |
7 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and omega-n-methylarginine
| Article | Year |
|---|---|
Oxygen-mediated regulation of neonatal and adult rabbit aortic tension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Isoquinolines; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxygen; Piperazines; Potassium Chloride; Protein Kinase C; Rabbits | 1992 |
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kidney Glomerulus; Kinetics; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphates; Phosphorylation; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Thromboxane A2 | 1994 |
Activation of purinergic P2Y2 receptors inhibits inducible NO synthase in cultured rat mesangial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Cells, Cultured; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Glomerular Mesangium; Indoles; Interferon-gamma; Lipopolysaccharides; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1998 |
Smoking, endothelial function, and Rho-kinase in humans.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Adult; Antioxidants; Ascorbic Acid; Endothelium, Vascular; Enzyme Inhibitors; Forearm; Humans; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Nitroprusside; omega-N-Methylarginine; Plethysmography; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Regional Blood Flow; rho-Associated Kinases; Smoking; Vasodilator Agents | 2005 |
Role of rho-kinase in the regulation of vascular tone in hypertensive renal transplant recipients.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Case-Control Studies; Dose-Response Relationship, Drug; Enzyme Activation; Forearm; Humans; Hypertension; Infusions, Intra-Arterial; Kidney Transplantation; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Plethysmography; Protein Kinase Inhibitors; Regional Blood Flow; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
The role of arginase and rho kinase in cardioprotection from remote ischemic perconditioning in non-diabetic and diabetic rat in vivo.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginase; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Ischemic Preconditioning; Male; Myocardial Reperfusion Injury; omega-N-Methylarginine; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction | 2014 |
Inhibition of Rho kinase protects from ischaemia-reperfusion injury via regulation of arginase activity and nitric oxide synthase in type 1 diabetes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginase; Arginine; Cytoprotection; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction | 2017 |