1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with nicardipine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.09) | 18.7374 |
| 1990's | 12 (54.55) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hagiwara, M; Hidaka, H; Watanabe, Y | 1 |
| Baker, AR; Thurston, H; Watt, PA | 1 |
| Marumo, F; Nonoguchi, H; Tomita, K | 2 |
| Hoshi, H; Mitsui, Y; Sasaki, H; Suzuki, T | 1 |
| Eguchi, S; Emori, T; Hirata, Y; Imai, T; Kanno, K; Marumo, F; Ohta, K; Shichiri, M | 1 |
| Asano, T; Hidaka, H; Ikegaki, I; Mochizuki, D; Satoh, S; Shibuya, M; Sugita, K; Suzuki, Y | 1 |
| Asano, T; Johshita, H; Matsui, T; Sugawa, M; Takuwa, Y | 1 |
| Kim, S; Koh, E; Miyashita, Y; Morimoto, S; Nabata, T; Ogihara, T | 1 |
| Hoshi, H; Mitsui, Y; Suzuki, T | 1 |
| Asano, T; Hidaka, H; Ikegaki, I; Satoh, S; Shibuya, M; Suzuki, T; Suzuki, Y; Tsuchiya, M | 1 |
| Asano, T; Hidaka, H; Ikegaki, I; Satoh, S; Shibuya, M; Suzuki, Y; Takayasu, M | 1 |
| Daniel, EE; Kwan, CY; Loke, JC; Low, AM | 1 |
| Asano, T; Itoh, S; Kaizu, H; Matsui, T | 1 |
| Katayama, T; Kuroda, H; Kyan, H; Murakami, N; Nakashima, M; Rahayu, EY | 1 |
| Abe, K; Egawa, T; Fujii, M; Fujiwara, M; Inada, K; Iwasaki, K; Matsumoto, Y; Mishima, K; Tsukikawa, H | 1 |
| Fan, YP; Puri, RN; Rattan, S | 1 |
| Abe, K; Egashira, N; Fujiwara, M; Inada, K; Iwasaki, K; Matsumoto, Y; Mishima, K; Miura, I; Tsukikawa, H | 1 |
| Nishizawa, S; Zhang, JH | 1 |
| Aggour, M; Moret, J; Pierot, L | 1 |
| Kasuya, H | 1 |
| Bieger, D; Ford, CA; Tabrizchi, R | 1 |
3 review(s) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and nicardipine
| Article | Year |
|---|---|
[Trend in the development of new inhibitors of cyclic nucleotide metabolism and their clinical application].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cilostazol; Cyclic AMP; Cyclic GMP; Depression, Chemical; Isoquinolines; Nicardipine; Platelet Aggregation Inhibitors; Tetrazoles; Vasodilator Agents; Vinca Alkaloids | 1991 |
[Basic research and treatment for cerebral vasospasm after subarachnoid hemorrhage: the present and future prospects].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acute Disease; Angioplasty, Balloon; Calcium Channel Blockers; Cell Membrane; Combined Modality Therapy; Endothelin-1; Hemoglobins; Humans; Muscle, Smooth, Vascular; Nicardipine; Nitric Oxide; Oxidative Stress; Subarachnoid Hemorrhage; Vasodilator Agents; Vasospasm, Intracranial; Verapamil | 2008 |
Vasospasm after aneurysmal subarachnoid hemorrhage: recent advances in endovascular management.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angioplasty, Balloon; Critical Care; Endovascular Procedures; Humans; Intensive Care Units; Milrinone; Nicardipine; Papaverine; Risk Factors; Subarachnoid Hemorrhage; Vasodilator Agents; Vasospasm, Intracranial; Verapamil | 2010 |
1 trial(s) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and nicardipine
| Article | Year |
|---|---|
Clinical trial of nicardipine prolonged-release implants for preventing cerebral vasospasm: multicenter cooperative study in Tokyo.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Aged; Calcium Channel Blockers; Cooperative Behavior; Drug Delivery Systems; Female; Humans; Japan; Male; Middle Aged; Nicardipine; Subarachnoid Hemorrhage; Treatment Outcome; Vasospasm, Intracranial | 2011 |
18 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and nicardipine
| Article | Year |
|---|---|
Calcium dependent and independent endothelin-1-induced contraction of human omentum vessels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Aged; Arteries; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Endothelins; Female; Humans; Isoquinolines; Male; Middle Aged; Nicardipine; Omentum; Piperazines; Protein Kinase C; Vasoconstriction | 1991 |
Inhibition of fluid transport by endothelin through protein kinase C in collecting duct of rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginine Vasopressin; Biological Transport; Cyclic AMP; Diglycerides; Endothelins; In Vitro Techniques; Indomethacin; Isoquinolines; Kidney Tubules, Collecting; Male; Nicardipine; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains | 1991 |
Effects of endothelin on peptide-dependent cyclic adenosine monophosphate accumulation along the nephron segments of the rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Arginine Vasopressin; Calcitonin; Calcium; Cyclic AMP; Endothelins; Glucagon; In Vitro Techniques; Indomethacin; Isoproterenol; Isoquinolines; Kidney Tubules; Loop of Henle; Nicardipine; Parathyroid Hormone; Peptides; Piperazines; Protein Kinase C; Rats | 1990 |
Endothelin-1 stimulates hypertrophy and contractility of neonatal rat cardiac myocytes in a serum-free medium. II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Calcium; Culture Media; Endothelins; Heart; Heart Rate; Hypertrophy; In Vitro Techniques; Isoquinolines; Male; Muscle Proteins; Myocardial Contraction; Myocardium; Nicardipine; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1991 |
Cellular mechanism of endothelin-1 release by angiotensin and vasopressin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Angiotensin II; Animals; Arginine Vasopressin; Calcium; Cattle; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Endothelins; Endothelium, Vascular; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoquinolines; Neomycin; Nicardipine; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine | 1991 |
Blockade of intracellular actions of calcium may protect against ischaemic damage to the gerbil brain.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain Ischemia; Calcimycin; Calcium Channel Blockers; Cell Death; Dogs; Gerbillinae; In Vitro Techniques; Isoquinolines; Male; Nicardipine; Rats; Rats, Inbred Strains; Vasoconstriction | 1991 |
Activation of the protein kinase C-mediated contractile system in canine basilar artery undergoing chronic vasospasm.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Basilar Artery; Chronic Disease; Dinoprost; Dogs; Enzyme Activation; In Vitro Techniques; Ischemic Attack, Transient; Isoquinolines; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Phorbol Esters; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Serotonin; Subarachnoid Hemorrhage; Sulfonamides | 1991 |
Endothelin stimulates Na+/H+ exchange in vascular smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Endothelins; Hydrogen; Hydrogen-Ion Concentration; Ion Exchange; Isoquinolines; Muscle, Smooth, Vascular; Nicardipine; Peptides; Piperazines; Protein Kinase C; Sodium | 1990 |
Endothelin stimulates hypertrophy and contractility of neonatal rat cardiac myocytes in a serum-free medium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cells, Cultured; Endothelins; In Vitro Techniques; Isoquinolines; Muscle Contraction; Muscle Proteins; Myocardium; Nicardipine; Peptides; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Type C Phospholipases | 1990 |
Vasodilator actions of HA1077 in vitro and in vivo putatively mediated by the inhibition of protein kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta, Thoracic; Calcium; Coronary Circulation; Dogs; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Isometric Contraction; Isoquinolines; Male; Muscle, Smooth; Nicardipine; Protein Kinase Inhibitors; Rabbits; Regional Blood Flow; Vasodilation | 1989 |
Mechanism of action of a novel antivasospasm drug, HA1077.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channel Blockers; Calcium Chloride; Dogs; Dose-Response Relationship, Drug; Female; Injections, Intra-Arterial; Injections, Intraventricular; Ischemic Attack, Transient; Isoproterenol; Isoquinolines; Male; Myocardial Contraction; Nicardipine; Rabbits; Vasodilation | 1987 |
Sensitivity to protein kinase C inhibitors of nicardipine-insensitive component of high K+ contracture in rat and guinea-pig aorta.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta, Thoracic; Calcium; Guinea Pigs; Hypertonic Solutions; In Vitro Techniques; Indomethacin; Isoquinolines; Male; Mannitol; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Nicardipine; Phentolamine; Piperazines; Polycyclic Compounds; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar | 1994 |
The role of active smooth-muscle contraction in the occurrence of chronic vasospasm in the canine two-hemorrhage model.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Basilar Artery; Dogs; Female; Ischemic Attack, Transient; Isoquinolines; Male; Models, Biological; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Papaverine; Piperazines; Protein Kinase C; Radiography; Subarachnoid Hemorrhage; Vasodilation | 1994 |
Involvement of distinct signaling pathways in activin-induced increases in FSH secretion and enlargement of FSH cell population in the rat pituitary.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Activins; Animals; Antibody Specificity; Bromodeoxyuridine; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Growth Substances; Humans; Inhibins; Nicardipine; Pituitary Gland, Anterior; Rats; Signal Transduction | 2000 |
Ameliorative effect of vasopressin-(4-9) through vasopressin V(1A) receptor on scopolamine-induced impairments of rat spatial memory in the eight-arm radial maze.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Calcium Channel Blockers; Dose-Response Relationship, Drug; Hemicholinium 3; Hippocampus; Hormone Antagonists; Injections, Intraventricular; Male; Maze Learning; Memory; Memory Disorders; Neurotransmitter Uptake Inhibitors; Nicardipine; Peptide Fragments; Pirenzepine; Rats; Rats, Wistar; Receptors, Vasopressin; Scopolamine | 2001 |
Comparison of angiotensin II (Ang II) effects in the internal anal sphincter (IAS) and lower esophageal sphincter smooth muscles.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anal Canal; Angiotensin II; Animals; Dose-Response Relationship, Drug; Drug Combinations; Esophagus; Female; Flavonoids; Genistein; Imidazoles; Losartan; Male; Muscle Contraction; Muscle, Smooth; Nicardipine; Opossums; Pyridines; Rabbits; Species Specificity; Tyrphostins | 2002 |
Ameliorative effect of NC-1900, a new AVP4-9 analog, through vasopressin V1A receptor on scopolamine-induced impairments of spatial memory in the eight-arm radial maze.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinases; Cholinergic Antagonists; Maze Learning; Memory; Microdialysis; Nicardipine; Nootropic Agents; Oligopeptides; Pirenzepine; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Receptors, Vasopressin; Scopolamine | 2003 |
Potassium-induced intermittent vasomotion in rat isolated pulmonary artery.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Animals; Barium; Indoles; Male; Mibefradil; Nicardipine; Niflumic Acid; Potassium; Potassium Channels; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Verapamil | 2011 |