1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with myelin oligodendrocyte glycoprotein (35-55) in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, J; Lu, CZ; Ma, CG; Sun, CH; Sun, YF; Xiao, BG; Yu, JZ | 1 |
| Feng, L; Feng, QJ; Guo, MF; Li, JL; Li, YH; Liu, CY; Ma, CG; Meng, J; Xiao, BG; Yang, WF; Yu, JZ | 1 |
| Chen, C; Li, YH; Ma, CG; Xiao, BG; Yu, JZ; Zhang, Q; Zhao, YF | 1 |
| Chai, Z; Feng, L; Feng, QJ; Guo, SD; Li, YH; Liu, CY; Ma, CG; Xiao, BG; Yang, WF; Yu, JZ; Yuan, HJ; Zhang, H | 1 |
| Chai, Z; Feng, L; Guo, SD; Li, YH; Liu, CY; Ma, CG; Mi, XT; Song, GB; Wang, Q; Xiao, BG; Yang, PW; Yu, JW | 1 |
5 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and myelin oligodendrocyte glycoprotein (35-55)
| Article | Year |
|---|---|
Therapeutic potential of experimental autoimmune encephalomyelitis by Fasudil, a Rho kinase inhibitor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analysis of Variance; Animals; Cell Proliferation; Cells, Cultured; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Gene Expression Regulation, Enzymologic; Glycoproteins; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Protein Kinase Inhibitors; rho-Associated Kinases; Severity of Illness Index; Spinal Cord; Spleen | 2010 |
The inhibition of Rho kinase blocks cell migration and accumulation possibly by challenging inflammatory cytokines and chemokines on astrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Astrocytes; CD4-Positive T-Lymphocytes; Cell Movement; Cells, Cultured; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Leukocytes, Mononuclear; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Nitrites; Peptide Fragments; Protein Kinase Inhibitors; Reactive Oxygen Species; rho-Associated Kinases | 2014 |
Fasudil regulates T cell responses through polarization of BV-2 cells in mice experimental autoimmune encephalomyelitis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anti-Inflammatory Agents; Cell Line; Cell Proliferation; Cell Shape; Cell Survival; Coculture Techniques; Cytokines; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Female; Inflammation Mediators; Lymphocyte Activation; Macrophages; Mice, Inbred C57BL; Microglia; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Phenotype; Protein Kinase Inhibitors; rho-Associated Kinases; T-Lymphocytes, Regulatory | 2014 |
Fasudil mediates cell therapy of EAE by immunomodulating encephalomyelitic T cells and macrophages.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginase; Cell- and Tissue-Based Therapy; Chemokine CCL20; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Regulation; Immunomodulation; Interleukin-10; Interleukin-12; Macrophages; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Nitric Oxide Synthase Type II; Peptide Fragments; Primary Cell Culture; Receptors, IgG; Signal Transduction; T-Lymphocytes; Toll-Like Receptor 4; Transcription Factor RelA; Transforming Growth Factor beta | 2015 |
Nasal delivery of Fasudil-modified immune cells exhibits therapeutic potential in experimental autoimmune encephalomyelitis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Administration, Intranasal; Animals; Cell- and Tissue-Based Therapy; Encephalomyelitis, Autoimmune, Experimental; Female; Leukocytes, Mononuclear; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Protein Kinase Inhibitors; Spinal Cord | 2019 |