1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with ml 9 in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (71.43) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hagiwara, M; Hidaka, H; Kato, M | 1 |
| Goto, S; Hagiwara, M; Hidaka, H; Hoshino, T; Hotta, T; Kobayashi, M; Murate, T; Saito, H | 1 |
| Brown, GE; Lanser, ME; Reed, EB | 1 |
| Hashioka, T; Kato, M | 1 |
| Hidaka, H; Kobayashi, R | 1 |
| Hidaka, H; Ishikawa, T; Tokumitsu, H | 1 |
| Badwey, JA; Curnutte, JT; Ding, J; Erickson, RW; Heyworth, PG | 1 |
| Hashioka, T | 1 |
| Itoh, M; Joh, T; Kato, T; Miyamoto, T; Okayama, N | 1 |
| Bonin, L; Chen, B; Griffith, OH; Hedberg, K; Mobley, PL | 1 |
| Hidaka, H; Iguchi, A; Niki, A; Niki, H; Niki, I; Okazaki, K; Saitoh, M; Tamagawa, T | 1 |
| Aussel, C; Breittmayer, JP; Dumaurier, MJ; Marhaba, R; Pelassy, C | 1 |
| Puschner, B; Schacht, J | 1 |
| Hidaka, H; Iida, Y; Matsukawa, Y; Miyazaki, JI; Niki, I; Nimura, Y; Onoda, K; Sakaguchi, H; Senda, T | 1 |
| Sakurada, K; Sasaki, Y; Seto, M | 1 |
| Lankisch, TO; Mitamura, K; Nozu, F; Owyang, C; Tsunoda, Y; Yoshida, H | 1 |
| Jin, N; Li, L; Rhoades, RA; Swartz, DR; Wang, Z; Yancey, KW; Zhang, D | 1 |
| Forer, A; Silverman-Gavrila, RV | 1 |
| Ito, K; Iwanaga, T; Nagumo, H; Nakamura, J; Sasaki, Y; Seto, M; Shimomura, E; Shindo, K; Shiraishi, M; Takuwa, Y | 1 |
| Shimoda, LA; Sylvester, JT; Weigand, L | 1 |
| Amobi, NI; Chung, IP; Smith, IC | 1 |
1 review(s) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and ml 9
| Article | Year |
|---|---|
[Molecular pharmacology of intracellular calcium signaling].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Azepines; Calcium; Cyclic AMP; Humans; Isoquinolines; Muscle Contraction; Muscle, Smooth; Myosins; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Second Messenger Systems; Sulfonamides | 1990 |
20 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and ml 9
| Article | Year |
|---|---|
Identification of a 80 kDa calmodulin-binding protein as a new Ca2+/calmodulin-dependent kinase by renaturation blotting assay (RBA).
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Azepines; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Calmodulin-Binding Proteins; Chromatography, Affinity; Cytosol; Isoquinolines; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Substrate Specificity; Sulfonamides | 1992 |
Thrombin-induced shape change in human megakaryoblastic leukemic cells, MEG-01, is mediated by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Azepines; Calcimycin; Cell Size; Cytochalasin B; Humans; Isoquinolines; Megakaryocytes; Phorbol Esters; Piperazines; Protein Kinase C; Thrombin; Tumor Cells, Cultured | 1992 |
Neutrophil CR3 expression and specific granule exocytosis are controlled by different signal transduction pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Azepines; Bucladesine; Calcimycin; Calcium; Calmodulin; Chlorpromazine; Exocytosis; Gelatinases; Gene Expression Regulation; Humans; In Vitro Techniques; Isoquinolines; Myosin-Light-Chain Kinase; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Neutrophils; Pepsin A; Piperazines; Protein Kinase Inhibitors; Receptors, Complement; Receptors, Complement 3b; Signal Transduction; Tetanus Toxin; Up-Regulation | 1991 |
Effects of inhibitors of intracellular messenger systems on amylase release from rat parotid gland.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amylases; Animals; Azepines; Calmodulin; Exocytosis; Isoquinolines; Male; Myosin-Light-Chain Kinase; Parotid Gland; Piperazines; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Second Messenger Systems; Sulfonamides | 1990 |
[Calmodulin dependent regulation of smooth muscle contraction].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Azepines; Calcium; Calmodulin; Isoquinolines; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Kinase; Piperazines; Sulfonamides; Thyroxine | 1990 |
Naphthalenesulphonamides block neutrophil superoxide production by intact cells and in a cell-free system: is myosin light chain kinase responsible for these effects?
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Azepines; Cell-Free System; Enzyme Inhibitors; Guinea Pigs; Humans; Isoquinolines; Myosin-Light-Chain Kinase; Naphthalenes; Neutrophils; Octoxynol; Piperazines; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Recepto-secretory mechanism in histamine-stimulated amylase release from rat parotid gland.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amylases; Animals; Azepines; Calmodulin; Cimetidine; Culture Techniques; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Isoquinolines; Male; Myosin-Light-Chain Kinase; Parotid Gland; Piperazines; Protein Kinase C; Pyrilamine; Rats; Rats, Wistar; Sulfonamides | 1995 |
Role of myosin light-chain kinase and protein kinase C in pepsinogen secretion from guinea pig gastric chief cells in monolayer culture.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Azepines; Calcium; Carbachol; Cells, Cultured; Colforsin; Gastric Mucosa; Guinea Pigs; Immunoenzyme Techniques; Ionomycin; Isoquinolines; Male; Microscopy, Electron; Myosin-Light-Chain Kinase; Pepsinogens; Piperazines; Protein Kinase C; Rabbits; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1994 |
Decreased phosphorylation of four 20-kDa proteins precedes staurosporine-induced disruption of the actin/myosin cytoskeleton in rat astrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Alkaloids; Animals; Animals, Newborn; Astrocytes; Azepines; Cells, Cultured; Cytoskeleton; Indoles; Isoquinolines; Myosin-Light-Chain Kinase; Myosins; Nerve Tissue Proteins; Phosphates; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rats; Staurosporine | 1994 |
Presence and possible involvement of Ca/calmodulin-dependent protein kinases in insulin release from the rat pancreatic beta cell.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Azepines; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Immunoblotting; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Kinetics; Male; Myosin-Light-Chain Kinase; Myosins; Phosphates; Phosphorus Radioisotopes; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Regulation of phospholipid biosynthesis by Ca(2+)-calmodulin-dependent protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Arachidonic Acid; Azepines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Endoplasmic Reticulum; Enzyme Inhibitors; Humans; Indoles; Jurkat Cells; Myosin-Light-Chain Kinase; Naphthalenes; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids | 1997 |
Calmodulin-dependent protein kinases mediate calcium-induced slow motility of mammalian outer hair cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Azepines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Hair Cells, Auditory, Outer; Ionomycin; Ionophores; Isoquinolines; Myosin-Light-Chain Kinase; Naphthalenes; Phosphorylation; Staurosporine; Sulfonamides | 1997 |
Myosin light-chain phosphorylation controls insulin secretion at a proximal step in the secretory cascade.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antibodies, Monoclonal; Azepines; Bacterial Proteins; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane Permeability; Cells, Cultured; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Homeostasis; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Myosin Heavy Chains; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Rats; Rats, Wistar; Streptolysins | 1997 |
Dynamics of myosin light chain phosphorylation at Ser19 and Thr18/Ser19 in smooth muscle cells in culture.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Androstadienes; Animals; Aorta; Azepines; Blotting, Western; Cell Line; Dinoprost; Enzyme Inhibitors; Kinetics; Mice; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Phosphoserine; Phosphothreonine; Rabbits; Staurosporine; Wortmannin | 1998 |
A possible role for Ca(2+)/calmodulin-dependent protein kinase IV during pancreatic acinar stimulus-secretion coupling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amylases; Animals; Azepines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Immunoblotting; Indole Alkaloids; Male; Myosin-Light-Chain Kinase; Pancreas; Phosphotransferases; Rats; Rats, Sprague-Dawley; Sincalide; Sulfonamides | 2000 |
Microtubule disruption modulates the Rho-kinase pathway in vascular smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Antineoplastic Agents; Aorta; Azepines; Calcium; Colchicine; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Male; Microtubules; Muscle Contraction; Muscle, Smooth, Vascular; Nocodazole; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Vasoconstrictor Agents | 2001 |
Effects of anti-myosin drugs on anaphase chromosome movement and cytokinesis in crane-fly primary spermatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anaphase; Animals; Azepines; Cell Division; Chromosomes; Diacetyl; Dimethyl Sulfoxide; Diptera; Male; Meiosis; Microscopy, Phase-Contrast; Myosins; Naphthalenes; Sex Chromosomes; Spermatocytes; Testis | 2001 |
Essential role of rho kinase in the Ca2+ sensitization of prostaglandin F(2alpha)-induced contraction of rabbit aortae.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Azepines; Calcium; Dinoprost; Enzyme Inhibitors; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Molecular Weight; Myosin Light Chains; Myosin-Light-Chain Phosphatase; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Rabbits; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Azepines; Endothelin-1; Enzyme Inhibitors; Genistein; Hypoxia; Indoles; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Male; Maleimides; Myosin-Light-Chain Kinase; Potassium Chloride; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pulmonary Artery; Pyridines; Pyrimidines; Rats; Rats, Wistar; rho-Associated Kinases; src-Family Kinases; Staurosporine; Vasoconstriction | 2006 |
Attenuation of contractility in rat epididymal vas deferens by Rho kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amides; Animals; Azepines; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Kinase; Norepinephrine; Potassium; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Purinergic P2 Receptor Agonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X; rho-Associated Kinases; Vas Deferens | 2006 |