Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and mevalonic acid

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with mevalonic acid in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Collado-Escobar, D; Mollinedo, F; Pérez-Sala, D1
Favre, G; Leveque, K; Sarrabayrouse, G; Synaeve, C; Tilkin-Mariamé, AF1
Horiuchi, N; Maeda, T1
Blaheta, R; Henrich, D; Lehnert, M; Marzi, I; Meder, F; Relja, B; Wang, M1

Other Studies

4 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and mevalonic acid

ArticleYear
Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease.
    The Journal of biological chemistry, 1995, Mar-17, Volume: 270, Issue:11

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Apoptosis; Cell Cycle; Cell Line; Cycloheximide; DNA, Neoplasm; Endodeoxyribonucleases; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Lovastatin; Mevalonic Acid; Piperazines; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1995
Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells.
    Neoplasia (New York, N.Y.), 2007, Volume: 9, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; ADP Ribose Transferases; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Atorvastatin; Benzamides; Botulinum Toxins; Cell Line, Tumor; Fas Ligand Protein; fas Receptor; Gene Expression Regulation, Neoplastic; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lymphocytes; Lymphoma; Melanoma, Experimental; Membrane Proteins; Methionine; Mevalonic Acid; Mice; Pyrroles; Recombinant Fusion Proteins; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Small Interfering

2007
Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation.
    Journal of biochemistry, 2009, Volume: 145, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3-L1 Cells; Adipocytes; Androstadienes; Animals; Benzamides; Cell Differentiation; Chromones; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme-Linked Immunosorbent Assay; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoquinolines; Leptin; Methionine; Mevalonic Acid; Mice; Morpholines; Polyisoprenyl Phosphates; Protein Prenylation; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Simvastatin; Sulfonamides; Wortmannin

2009
Simvastatin modulates the adhesion and growth of hepatocellular carcinoma cells via decrease of integrin expression and ROCK.
    International journal of oncology, 2011, Volume: 38, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Adhesion; Cell Communication; Cell Proliferation; Cells, Cultured; Down-Regulation; Drug Evaluation, Preclinical; Endothelial Cells; Hep G2 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Integrins; Liver Neoplasms; Mevalonic Acid; rho-Associated Kinases; Simvastatin

2011