Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and lysophosphatidic acid

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with lysophosphatidic acid in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hata, Y; Ishibashi, T; Kano, K; Kita, T; Miura, M; Nakao, S; Noda, Y; Shimokawa, H1
Hashimoto, K; Kawase, C; Kimura, T; Mabuchi, S; Morishige, K; Ogata, S; Ooyagi, C; Sakata, M; Sawada, K1
Boergermann, C; Jakobs, KH; Lümmen, G; Rübben, H; Sanders, H; Schmidt, M; vom Dorp, F1
Asano, T; Hitomi, A; Ikegaki, I; Kawasaki, K; Satoh, S1
Jin, T; Li, L; Liu, L; Ng, DS; Tam, L1
Cai, XY; Chen, J; Fan, JQ; Li, ZY; Ren, JH; Wu, G; Xia, Y; Zhang, LL; Zhang, RG; Zhu, F1
Bicker, G; Scheiblich, H1
Lei, S; Li, C; Liu, PP; Song, R; Tang, DD; Wu, SJ; Zhang, YQ1

Other Studies

8 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and lysophosphatidic acid

ArticleYear
Transforming growth factor-beta2 and connective tissue growth factor in proliferative vitreoretinal diseases: possible involvement of hyalocytes and therapeutic potential of Rho kinase inhibitor.
    Diabetes, 2007, Volume: 56, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Connective Tissue Growth Factor; Gene Expression Regulation; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Recombinant Proteins; Retinal Diseases; rho-Associated Kinases; RNA, Messenger; Transforming Growth Factor beta2; Vitrectomy; Vitreous Body

2007
Fasudil inhibits lysophosphatidic acid-induced invasiveness of human ovarian cancer cells.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2009, Volume: 19, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antineoplastic Agents; Carcinoma; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Lysophospholipids; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Ovarian Neoplasms; rho-Associated Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2009
Inhibition of Rho-kinase abrogates migration of human transitional cell carcinoma cells: results of an in vitro study.
    Urologia internationalis, 2011, Volume: 86, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Amides; Bacterial Proteins; Bacterial Toxins; Calcium; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Movement; Fura-2; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Lysophospholipids; Mutation; Pertussis Toxin; Phalloidine; Protein Kinase Inhibitors; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Type C Phospholipases

2011
Fasudil protects cultured N1E-115 cells against lysophosphatidic acid-induced neurite retraction through inhibition of Rho-kinase.
    Brain research bulletin, 2011, Feb-01, Volume: 84, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Humans; Lysophospholipids; Mice; Neurites; Neurons; Protein Kinase Inhibitors; rho-Associated Kinases

2011
Wnt-signaling mediates the anti-adipogenic action of lysophosphatidic acid through cross talking with the Rho/Rho associated kinase (ROCK) pathway.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2011, Volume: 89, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Adipogenesis; Amides; Animals; beta Catenin; Gene Expression Regulation; Lysophospholipids; Mice; PPAR gamma; Pyridines; Receptor Cross-Talk; rho-Associated Kinases; RNA, Messenger; Time Factors; Transcriptional Activation; Wnt Proteins; Wnt Signaling Pathway

2011
Rho Kinase Inhibitor Fasudil Suppresses the Vasculogenic Mimicry of B16 Mouse Melanoma Cells Both In Vitro and In Vivo.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:7

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Lysophospholipids; Male; Melanoma, Experimental; Mice, Inbred C57BL; Microscopy, Confocal; Neoplasm Transplantation; Neovascularization, Pathologic; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Tumor Burden

2015
Regulation of Microglial Phagocytosis by RhoA/ROCK-Inhibiting Drugs.
    Cellular and molecular neurobiology, 2017, Volume: 37, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Biological Assay; Cell Line; Down-Regulation; Humans; Ibuprofen; Lysophospholipids; Mice; Microglia; Nitric Oxide; Phagocytosis; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction

2017
Targeting the RhoA-ROCK pathway to regulate T-cell homeostasis in hypoxia-induced pulmonary arterial hypertension.
    Pulmonary pharmacology & therapeutics, 2018, Volume: 50

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Hypertension, Pulmonary; Hypoxia; Interleukin-10; Interleukin-17; Lysophospholipids; Male; Pulmonary Artery; Random Allocation; Rats; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; T-Lymphocytes, Regulatory; Th17 Cells; Vascular Remodeling

2018