Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and lrrk2-in1

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with lrrk2-in1 in 1 studies

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Froehlich, T; Gillardon, F; Gloeckner, CJ; Hengerer, B; Kremmer, E; Ueffing, M	1

Other Studies

1 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and lrrk2-in1

Article	Year
ATP-competitive LRRK2 inhibitors interfere with monoclonal antibody binding to the kinase domain of LRRK2 under native conditions. A method to directly monitor the active conformation of LRRK2? Journal of neuroscience methods, 2013, Mar-30, Volume: 214, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Benzodiazepinones; Binding, Competitive; Enzyme Activation; Epitopes; HEK293 Cells; Humans; Immunoprecipitation; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Parkinson Disease; Phosphorylation; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Pyrimidines; Recombinant Proteins; Swiss 3T3 Cells	2013

Article

Year

ATP-competitive LRRK2 inhibitors interfere with monoclonal antibody binding to the kinase domain of LRRK2 under native conditions. A method to directly monitor the active conformation of LRRK2?

Journal of neuroscience methods, 2013, Mar-30, Volume: 214, Issue:1

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Benzodiazepinones; Binding, Competitive; Enzyme Activation; Epitopes; HEK293 Cells; Humans; Immunoprecipitation; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Parkinson Disease; Phosphorylation; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Pyrimidines; Recombinant Proteins; Swiss 3T3 Cells

2013