1-(5-isoquinolinesulfonyl)-2-methylpiperazine and kt 5720

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with kt 5720 in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (57.89)18.2507
2000's7 (36.84)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berridge, MV; Tan, AS1
Pratt, MM; Salathe, M; Wanner, A1
Iitaka, M; Ishii, J; Kitahama, S1
Audesirk, G; Cabell, L1
Goligorsky, MS; Malbon, CC; Wang, Hy1
Ardenghi, P; Izquierdo, I; Izquierdo, LA; Medina, JH; Netto, CA; Quevedo, J; Schröder, N1
Coleman, R; Roma, MG; Shaw, R; Stone, V1
Day, BN; Green, KM; Kim, JH; Prather, RS; Wang, WH1
Kamei, J; Ohsawa, M; Tanaka, S1
Ito, Y; Marunaka, Y; Niisato, N1
Izquierdo, I; Medina, JH; Netto, CA; Schröder, N1
Ardenghi, P; Barros, DM; Izquierdo, I; Izquierdo, LA; Medinam, JH; Mello e Souza, T; Rodrigues, C; Sant'Anna, MK; Vianna, M1
Gemba, M; Kohda, Y1
Hirsh, JK; Silinsky, EM1
Coleman, R; Elias, E; Milkiewicz, P; Roma, MG1
Blanquet, PR; Derer, P; Mariani, J1
Abe, K; Misawa, M1
Huang, SH; Shen, WJ; Wang, SM; Yeo, HL1
Feng, Y; Hirasawa, Y; Nagamatsu, T; Nagao, T; Nishiyama, T1

Other Studies

19 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and kt 5720

ArticleYear
The protein kinase C inhibitor, calphostin C, inhibits succinate-dependent mitochondrial reduction of MTT by a mechanism that does not involve protein kinase C.
    Biochemical and biophysical research communications, 1992, Jun-30, Volume: 185, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow; Carbazoles; Cell Division; Cell Line; Coloring Agents; DNA Replication; Indoles; Isoquinolines; Kinetics; Mice; Mice, Inbred C3H; Mitochondria; Naphthalenes; Oxidation-Reduction; Piperazines; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Succinates; Tetrazolium Salts; Thiazoles; Thymidine

1992
Protein kinase C-dependent phosphorylation of a ciliary membrane protein and inhibition of ciliary beating.
    Journal of cell science, 1993, Volume: 106 ( Pt 4)

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Annexins; Carbazoles; Cell Fractionation; Cilia; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Erythrocytes; Indoles; Isoquinolines; Membrane Proteins; Movement; Phosphorylation; Phosphoserine; Phosphotyrosine; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Sheep; Tetradecanoylphorbol Acetate; Trachea; Tyrosine

1993
Involvement of protein kinase A and C in the production of interleukin-1 alpha-induced prostaglandin E2 from mouse osteoblast-like cell line, MC3T3-E1.
    Biochimica et biophysica acta, 1994, Mar-10, Volume: 1221, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dinoprostone; Humans; Indoles; Indomethacin; Interleukin-1; Isoquinolines; Kinetics; Mice; Osteoblasts; Piperazines; Protein Kinase C; Pyrroles; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate

1994
Effects of selective inhibition of protein kinase C, cyclic AMP-dependent protein kinase, and Ca(2+)-calmodulin-dependent protein kinase on neurite development in cultured rat hippocampal neurons.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1993, Volume: 11, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Axons; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbazoles; Cells, Cultured; Dendrites; Female; Hippocampus; Imidazoles; Indoles; Isoquinolines; Naphthalenes; Neurites; Piperazines; Polycyclic Compounds; Pregnancy; Protein Kinase C; Protein Kinase Inhibitors; Pyramidal Tracts; Pyrroles; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

1993
Temporal activation of Ca2+-calmodulin-sensitive protein kinase type II is obligate for adipogenesis.
    The Journal of biological chemistry, 1997, Jan-17, Volume: 272, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Adipose Tissue; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Indoles; Mice; Pyrroles; Sulfonamides

1997
Systemic administration of ACTH or vasopressin reverses the amnestic effect of posttraining beta-endorphin or electroconvulsive shock but not that of intrahippocampal infusion of protein kinase inhibitors.
    Neurobiology of learning and memory, 1997, Volume: 68, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arousal; beta-Endorphin; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cosyntropin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fear; Hippocampus; Indoles; Injections, Intraperitoneal; Lypressin; Male; Mental Recall; Neural Pathways; Pyrroles; Rats; Rats, Wistar; Retention, Psychology

1997
Vasopressin-induced disruption of actin cytoskeletal organization and canalicular function in isolated rat hepatocyte couplets: possible involvement of protein kinase C.
    Hepatology (Baltimore, Md.), 1998, Volume: 28, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Antioxidants; Bile Canaliculi; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cells, Cultured; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Indoles; Leupeptins; Liver; Male; Microscopy, Electron, Scanning; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrroles; Rats; Rats, Wistar; Tight Junctions; Vacuoles; Vasopressins

1998
Effect of myosin light chain kinase, protein kinase A, and protein kinase C inhibition on porcine oocyte activation.
    Biology of reproduction, 1999, Volume: 61, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Androstadienes; Animals; Carbazoles; Cell Nucleus; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytoplasmic Granules; Enzyme Inhibitors; Exocytosis; Female; Indoles; Microscopy, Electron; Myosin-Light-Chain Kinase; Oocytes; Protein Kinase C; Pyrroles; Swine; Wortmannin

1999
Possible mechanisms for insulin-induced attenuation of the antinociceptive effect of [D-Ala2, N-MePhe4, Gly-ol5]enkephalin.
    European journal of pharmacology, 1999, Jun-04, Volume: 373, Issue:2-3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analgesics, Opioid; Animals; Benzoquinones; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Inhibitors; Hypoglycemic Agents; Indoles; Injections, Intraventricular; Insulin; Lactams, Macrocyclic; Male; Mice; Mice, Inbred ICR; Naphthalenes; Pain Measurement; Protein Kinase C; Pyrroles; Quinones; Rifabutin; Time Factors

1999
Effects of PKA inhibitors, H-compounds, on epithelial Na+ channels via PKA-independent mechanisms.
    Life sciences, 1999, Volume: 65, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Indoles; Isoquinolines; Myristic Acid; Pulmonary Alveoli; Pyrroles; Rats; Rats, Wistar; Sodium; Sodium Channels; Structure-Activity Relationship; Sulfonamides; Terbutaline

1999
Novelty causes time-dependent retrograde amnesia for one-trial avoidance in rats through NMDA receptor- and CaMKII-dependent mechanisms in the hippocampus.
    The European journal of neuroscience, 1999, Volume: 11, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; Amnesia, Retrograde; Animals; Avoidance Learning; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Environment; Enzyme Inhibitors; Hippocampus; Indoles; Injections; Male; Psychomotor Performance; Pyrroles; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors

1999
Short- and long-term memory are differentially affected by metabolic inhibitors given into hippocampus and entorhinal cortex.
    Neurobiology of learning and memory, 2000, Volume: 73, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Animals; Avoidance Learning; Carbazoles; Entorhinal Cortex; Enzyme Inhibitors; Flavonoids; Guanylate Cyclase; Hippocampus; Indoles; Inhibition, Psychological; Male; Memory; Memory, Short-Term; Phenols; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Sodium Chloride; Staurosporine

2000
Modulation by cyclic AMP and phorbol myristate acetate of cephaloridine-induced injury in rat renal cortical slices.
    Japanese journal of pharmacology, 2001, Volume: 85, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbazoles; Carcinogens; Cephaloridine; Cephalosporins; Cyclic AMP; Enzyme Inhibitors; Free Radicals; Gluconeogenesis; In Vitro Techniques; Indoles; Kidney Cortex; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; p-Aminohippuric Acid; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate

2001
Inhibition of spontaneous acetylcholine secretion by 2-chloroadenosine as revealed by a protein kinase inhibitor at the mouse neuromuscular junction.
    British journal of pharmacology, 2002, Volume: 135, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Chloroadenosine; Acetylcholine; Animals; Carbazoles; Carrier Proteins; Cell Membrane Permeability; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Indoles; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Neuromuscular Junction; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrroles; Staurosporine; Thionucleotides

2002
Hepatoprotection with tauroursodeoxycholate and beta muricholate against taurolithocholate induced cholestasis: involvement of signal transduction pathways.
    Gut, 2002, Volume: 51, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analysis of Variance; Animals; Bucladesine; Calcium; Carbazoles; Chelating Agents; Cholagogues and Choleretics; Cholestasis; Cholic Acids; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Indoles; Liver; Male; Protein Kinase C; Pyrroles; Rats; Signal Transduction; Staurosporine; Taurochenodeoxycholic Acid; Taurolithocholic Acid

2002
A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus.
    Neuroscience, 2003, Volume: 118, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Androstadienes; Animals; Antibodies; Benzophenanthridines; Benzopyrans; Blotting, Western; Brain-Derived Neurotrophic Factor; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbazoles; Cell Nucleus; Chromones; Cyclic AMP Response Element-Binding Protein; Cytosol; Enzyme Inhibitors; Flavonoids; Hippocampus; Imidazoles; Immunohistochemistry; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Male; Morpholines; Naphthalenes; Phenanthridines; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rats; Signal Transduction; Time Factors; Tyrphostins; Wortmannin

2003
Astrocyte stellation induced by Rho kinase inhibitors in culture.
    Brain research. Developmental brain research, 2003, Jun-12, Volume: 143, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Amides; Animals; Astrocytes; Carbazoles; Cell Size; Cells, Cultured; Cerebral Cortex; Colchicine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gout Suppressants; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Phalloidine; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rats; rho-Associated Kinases

2003
Signaling pathway of magnolol-stimulated lipolysis in sterol ester-loaded 3T3-L1 preadipocyes.
    Journal of cellular biochemistry, 2004, Apr-01, Volume: 91, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3-L1 Cells; Adipocytes; Animals; Benzylamines; Biphenyl Compounds; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Flavonoids; Glycerol; Hydroxycholesterols; Indoles; Lignans; Lipolysis; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Naphthalenes; Oleic Acid; Phosphorylation; Protein Kinase C; Pyrroles; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Vacuoles

2004
Involvement of protein kinase C in reduction of aggregated protein and phosphorylation of CREB in glomeruli.
    Experimental animals, 2012, Volume: 61, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbazoles; Cattle; CREB-Binding Protein; Cyclic AMP; Enzyme Inhibitors; Kidney Glomerulus; Male; Mice; Mice, Inbred ICR; Oxidative Phosphorylation; Protein Kinase C; Pyrroles; Serum Albumin, Bovine

2012