Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and isoquinoline

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with isoquinoline in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bossemeyer, D; Engh, RA; Girod, A; Huber, R; Kinzel, V1
Adam, J; Black, D; Boucharens, S; Brown, AR; de Man, J; Epemolu, O; Fletcher, D; Huggett, M; Jones, P; Laats, S; Lyons, A; Morphy, R; Ray, P; Sherborne, B; Sherry, L; Straten, Nv; Westwood, P; Wright, J; York, M1
Barroso, RCR; Bastos, ITS; Costa, FN; Fernandes, PD; Ferreira, FF; Fraga, CAM; Guerra, FS; Mermelstein, CDS; Oliveira, RG1

Other Studies

3 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and isoquinoline

ArticleYear
Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity.
    The Journal of biological chemistry, 1996, Oct-18, Volume: 271, Issue:42

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Binding Sites; Casein Kinase II; Casein Kinases; Cattle; Crystallography, X-Ray; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Glycine; Isoquinolines; Myosin-Light-Chain Kinase; Protein Conformation; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Sulfonamides

1996
Optimisation of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.
    Bioorganic & medicinal chemistry letters, 2011, Feb-15, Volume: 21, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amines; Animals; Disease Models, Animal; Hypertension; Isoquinolines; Models, Chemical; Models, Molecular; Piperidines; Protein Kinase Inhibitors; Quinolones; Rats; rho-Associated Kinases; Structure-Activity Relationship

2011
Synthesis and pharmacological evaluation of novel isoquinoline N-sulphonylhydrazones designed as ROCK inhibitors.
    Journal of enzyme inhibition and medicinal chemistry, 2018, Volume: 33, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line, Tumor; Female; Humans; Hydrazones; Isoquinolines; Models, Molecular; Powder Diffraction; Protein Kinase Inhibitors; rho-Associated Kinases; Spectrum Analysis

2018