Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and inositol 1,4,5-trisphosphate

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with inositol 1,4,5-trisphosphate in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19907 (20.00)18.7374
1990's27 (77.14)18.2507
2000's1 (2.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kitamura, K; Kuriyama, H; Teramoto, N; Xiong, Z1
Fujii, T; Hashizume, T; Sato, T1
Daniels, AJ; Humberto Viveros, O; Lazarowski, ER; Matthews, JE1
Nozawa, Y; Okano, Y; Yada, Y1
Bitar, KN; Cease, KB; Hailat, N; Kaminski, MS; Strahler, JR1
Eguchi, S; Emori, T; Hirata, Y; Imai, T; Kanno, K; Marumo, F; Ohta, K; Shichiri, M1
Kanaho, Y; Miura, K; Nozawa, Y; Yamada, K1
Grunstein, MM; Pawlowski, NA; Rosenberg, SM; Schramm, CM1
Dean, WL; Klein, JB; McLeish, KR; Schepers, TM; Sonnenfeld, G1
Putney, JW; Sugiya, H1
De Pont, JJ; Van den Broek, BA; Van Os, CH; Willems, PH1
Nachmias, VT; Yoshida, K1
Bertrand, W; Mordhorst, M; Morrison, AR; Portilla, D1
Fuse, I; Tai, HH1
Lupu-Meiri, M; Oron, Y; Shapira, H1
Caramelo, C; Schrier, RW; Tsai, P1
Nishida, A; Shimizu, M; Yamawaki, S1
Dehaye, JP; Turner, RJ; Valdez, IH1
Amaral, J; Behar, J; Biancani, P; De Petris, G; Yu, P1
Behar, J; Biancani, P; Bitar, KN; Harnett, KM; Hillemeier, C; Rhim, BY; Sohn, UD1
Behar, J; Biancani, P; De Petris, G; Harnett, KM; Yu, P1
Dibirdik, I; Ledbetter, JA; Myers, DE; Schieven, GL; Song, CW; Tuel-Ahlgren, LM; Uckun, FM1
Bertrand, N; McCarron, R; Spatz, M; Stanimirovic, DB1
Harada, H; Motomura, A; Suketa, Y; Suzuki, S; Tai, H1
DelValle, J; Osburn, J; Wang, L; Wilson, EJ1
Biancani, P; Bitar, KN; Hillemeier, C; Sohn, U1
Chock, PB; Huang, CY; Tekle, E; Zhu, DM1
Artemenko, IP; Hokin, LE; Los, GV1
Babich, M; Foti, LR; Mathias, KL1
Behar, J; Biancani, P; Kim, N; Rich, H; Sohn, UD1
Ishiguro, M; Kohsaka, S; Morimoto, T; Ohsawa, I; Takamura, C1
Behar, J; Biancani, P; Chen, Q; Harnett, K; Xiao, Z; Yu, P1
Ahuja, N; Batra, S; Bhatnagar, R; Goila, R; Gupta, P; Waheed, SM1
Akamatsu, N; Higaki, T; Imamura, H; Komatsu, S; Kono, Y; Nakagawa, M; Sato, T; Sawada, S; Tada, Y; Tamagaki, T; Toratani, A; Tsuda, Y; Tsuji, H; Yamasaki, S1
Hirano, Y; Hiraoka, M; Lin, J; Zhang, S1

Other Studies

35 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and inositol 1,4,5-trisphosphate

ArticleYear
Roles of inositol trisphosphate and protein kinase C in the spontaneous outward current modulated by calcium release in rabbit portal vein.
    Pflugers Archiv : European journal of physiology, 1992, Volume: 421, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Caffeine; Calcium Channels; Guanosine; Heparin; Inositol 1,4,5-Trisphosphate; Isoquinolines; Male; Membrane Potentials; Muscle, Smooth, Vascular; Neomycin; Norepinephrine; Phorbol 12,13-Dibutyrate; Piperazines; Portal Vein; Protein Kinase Inhibitors; Protein Kinases; Rabbits

1992
Sphingosine enhances platelet aggregation through an increase in phospholipase C activity by a protein kinase C-independent mechanism.
    The Biochemical journal, 1992, Feb-15, Volume: 282 ( Pt 1)

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Animals; Arachidonic Acid; Blood Platelets; Calcium; Cell Membrane; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; Piperazines; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Rabbits; Sphingosine; Staurosporine; Thrombin; Type C Phospholipases

1992
Characterization of the neuropeptide Y-induced intracellular calcium release in human erythroleukemic cells.
    Molecular pharmacology, 1992, Volume: 41, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Enzyme Activation; Erythrocytes; Fura-2; Humans; Inositol 1,4,5-Trisphosphate; Isoquinolines; Leukemia, Erythroblastic, Acute; Neuropeptide Y; Piperazines; Protein Kinase C; Spectrometry, Fluorescence; Terpenes; Thapsigargin; Tumor Cells, Cultured

1992
Ganglioside GQ1b-induced terminal differentiation in cultured mouse keratinocytes. Phosphoinositide turnover forms the onset signal.
    The Biochemical journal, 1991, Nov-01, Volume: 279 ( Pt 3)

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Biological Transport; Calcium; Cell Differentiation; Cells, Cultured; DNA; Gangliosides; Growth Substances; Inositol 1,4,5-Trisphosphate; Isoquinolines; Keratinocytes; Mice; Mice, Inbred BALB C; Phosphatidylinositols; Piperazines; Signal Transduction; Tetradecanoylphorbol Acetate; Transglutaminases

1991
Hsp27 is a mediator of sustained smooth muscle contraction in response to bombesin.
    Biochemical and biophysical research communications, 1991, Dec-31, Volume: 181, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anal Canal; Animals; Antibodies, Monoclonal; Bombesin; Cell Membrane Permeability; Electrophoresis, Gel, Two-Dimensional; Heat-Shock Proteins; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoquinolines; Muscle Contraction; Muscle, Smooth; Phosphates; Phosphorus Radioisotopes; Piperazines; Protein Kinase C; Rabbits; Substance P; Sulfonamides

1991
Cellular mechanism of endothelin-1 release by angiotensin and vasopressin.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Angiotensin II; Animals; Arginine Vasopressin; Calcium; Cattle; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Endothelins; Endothelium, Vascular; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoquinolines; Neomycin; Nicardipine; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine

1991
Antigen-induced phospholipase D activation in rat mast cells is independent of protein kinase C.
    Biochemical and biophysical research communications, 1991, Feb-28, Volume: 175, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antigens, Helminth; Ascaris; Enzyme Activation; Enzyme Induction; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; Mast Cells; Myristic Acid; Myristic Acids; Phospholipase D; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate

1991
Mechanisms of action of endothelin 1 in maturing rabbit airway smooth muscle.
    The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Aging; Animals; Dinoprostone; Eicosanoids; Endothelins; In Vitro Techniques; Indomethacin; Inositol 1,4,5-Trisphosphate; Isoquinolines; Muscle Contraction; Muscle Development; Muscle Relaxation; Muscle, Smooth; Piperazines; Protein Kinase Inhibitors; Rabbits; Signal Transduction; Trachea

1991
Role of intracellular calcium concentration and protein kinase C activation in IFN-gamma stimulation of U937 cells.
    Journal of immunology (Baltimore, Md. : 1950), 1990, Jun-01, Volume: 144, Issue:11

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Differentiation; Antigens, Differentiation, Myelomonocytic; Antigens, Surface; Biological Transport; Calcium; Cell Compartmentation; Cell Line; Enzyme Activation; Gallic Acid; HLA-DR Antigens; Humans; Inositol 1,4,5-Trisphosphate; Interferon-gamma; Ionomycin; Isoquinolines; Macrophage-1 Antigen; Macrophages; Piperazines; Protein Kinase C; Receptors, Complement; Receptors, Fc; Receptors, IgG; Signal Transduction; Tetradecanoylphorbol Acetate

1990
Protein kinase C-dependent and -independent mechanisms regulating the parotid substance P receptor as revealed by differential effects of protein kinase C inhibitors.
    The Biochemical journal, 1988, Dec-01, Volume: 256, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbazoles; Indole Alkaloids; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoquinolines; Male; Parotid Gland; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Sugar Phosphates

1988
Inhibition of inositol 1,4,5-trisphosphate-induced Ca2+ release in permeabilized pancreatic acinar cells by hormonal and phorbol ester pretreatment.
    The Journal of biological chemistry, 1989, Jun-15, Volume: 264, Issue:17

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Carbachol; Cell Membrane Permeability; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoquinolines; Kinetics; Pancreas; Piperazines; Protein Kinase Inhibitors; Rabbits; Sincalide; Sugar Phosphates; Tetradecanoylphorbol Acetate

1989
Phorbol ester stimulates calcium sequestration in saponized human platelets.
    The Journal of biological chemistry, 1987, Nov-25, Volume: 262, Issue:33

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Alprostadil; Benzofurans; Biological Transport, Active; Blood Platelets; Calcimycin; Calcium; Calcium Radioisotopes; Chelating Agents; Fura-2; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin

1987
Protein kinase C modulates phospholipase C and increases arachidonic acid release in bradykinin stimulated MDCK cells.
    Biochemical and biophysical research communications, 1988, May-31, Volume: 153, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Cell Line; Dogs; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoquinolines; Kidney; Piperazines; Protein Kinase C; Type C Phospholipases

1988
Does protein kinase C activation mediate thrombin-induced arachidonate release in human platelets?
    Biochimica et biophysica acta, 1988, Oct-28, Volume: 972, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Calcium; Enzyme Activation; Gallic Acid; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoquinolines; Piperazines; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane B2

1988
Hemispheric asymmetry of rapid chloride responses to inositol trisphosphate and calcium in Xenopus oocytes.
    FEBS letters, 1988, Nov-21, Volume: 240, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cell Compartmentation; Chlorides; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoquinolines; Oocytes; Piperazines; Protein Kinase C; Sugar Phosphates; Xenopus laevis

1988
Mechanism of cellular effect of phorbol esters on action of arginine vasopressin and angiotensin II on rat vascular smooth muscle cells in culture.
    The Biochemical journal, 1988, Sep-15, Volume: 254, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Arginine Vasopressin; Calcium; Cells, Cultured; Depression, Chemical; Ethers; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Isoquinolines; Muscle, Smooth, Vascular; Piperazines; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1988
Forskolin and phorbol myristate acetate inhibit intracellular Ca2+ mobilization induced by amitriptyline and bradykinin in rat frontocortical neurons.
    Journal of neurochemistry, 1993, Volume: 61, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Amitriptyline; Animals; Bradykinin; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Frontal Lobe; Imipramine; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; Neurons; Piperazines; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate

1993
Beta-adrenergic stimulation and cAMP mobilize Ca2+ from an IP3-insensitive pool in rat submandibular granular ducts.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Alkaloids; Animals; Atenolol; Atropine; Calcium; Carbachol; Cyclic AMP; Epinephrine; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Isoquinolines; Kinetics; Male; Phentolamine; Piperazines; Propanolamines; Propranolol; Protein Kinase C; Protein Kinase Inhibitors; Putrescine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Staurosporine; Submandibular Gland

1993
Cholecystokinin-coupled intracellular signaling in human gallbladder muscle.
    Gastroenterology, 1994, Volume: 106, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Benzimidazoles; Calmodulin; Cholecystokinin; Diglycerides; Enzyme Activation; Gallbladder; Heparin, Low-Molecular-Weight; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Isoquinolines; Muscle Contraction; Muscle, Smooth; Piperazines; Protein Kinase C; Signal Transduction

1994
Differential signal transduction pathways in cat lower esophageal sphincter tone and response to ACh.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Analysis of Variance; Animals; Benzimidazoles; Calmodulin; Cats; Diglycerides; Dose-Response Relationship, Drug; Electric Stimulation; Esophagus; Estrenes; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoquinolines; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Piperazines; Protein Kinase Inhibitors; Pyrrolidinones; Signal Transduction; Type C Phospholipases

1994
Interaction between signal transduction pathways contributing to gallbladder tonic contraction.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calmodulin; Cats; Diglycerides; Female; Gallbladder; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Isoquinolines; Male; Models, Biological; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Myosin-Light-Chain Kinase; Myosins; Phosphorylation; Piperazines; Protein Kinase C; Signal Transduction; Strontium; Sulfonamides; Tetrodotoxin

1993
Tyrosine phosphorylation is a mandatory proximal step in radiation-induced activation of the protein kinase C signaling pathway in human B-lymphocyte precursors.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-01, Volume: 90, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; B-Lymphocytes; Benzoquinones; Cell Line; Cesium Radioisotopes; Dose-Response Relationship, Radiation; Enzyme Activation; Gamma Rays; Humans; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; Lactams, Macrocyclic; NF-kappa B; Phosphorylation; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; Signal Transduction; Tumor Cells, Cultured

1993
Endothelins release 51Cr from cultured human cerebromicrovascular endothelium.
    Biochemical and biophysical research communications, 1993, Feb-26, Volume: 191, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Cerebrovascular Circulation; Chromium Radioisotopes; Dexamethasone; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Humans; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; L-Lactate Dehydrogenase; Microcirculation; Piperazines; Protein Kinase Inhibitors; Ryanodine; Tetradecanoylphorbol Acetate; Verapamil

1993
Extracellular ATP-induced regulation of epidermal growth factor signaling in cultured renal LLC-PK1 cells.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Animals; Cell Line; Cell Membrane; Cytosol; Epidermal Growth Factor; ErbB Receptors; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kidney; Kinetics; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate

1993
Epidermal growth factor inhibits carbachol-stimulated canine parietal cell function via protein kinase C.
    Gastroenterology, 1996, Volume: 110, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminopyrine; Animals; Calcium; Carbachol; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dogs; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Gastric Acid; Inositol 1,4,5-Trisphosphate; Isoquinolines; Parasympathomimetics; Parietal Cells, Gastric; Piperazines; Protein Kinase C; Receptors, Muscarinic; Staurosporine; Sulfonamides

1996
Protein kinase C mediates spontaneous tone in the cat lower esophageal sphincter.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cats; Diglycerides; Esophagogastric Junction; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoquinolines; Male; Muscle Contraction; Piperazines; Protein Kinase C; Type C Phospholipases; Vasoactive Intestinal Peptide

1996
Reversible phosphorylation as a controlling factor for sustaining calcium oscillations in HeLa cells: Involvement of calmodulin-dependent kinase II and a calyculin A-inhibitable phosphatase.
    Biochemistry, 1996, Jun-04, Volume: 35, Issue:22

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Binding Sites; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Enzyme Inhibitors; Ethers, Cyclic; HeLa Cells; Histamine; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoquinolines; Maleimides; Marine Toxins; Molecular Sequence Data; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Protein Kinase C; Receptors, Cytoplasmic and Nuclear; Ryanodine; Spectrometry, Fluorescence; Staurosporine; Sulfonamides

1996
Phosphoinositide signalling in human neuroblastoma cells: biphasic effect of Li+ on the level of the inositolphosphate second messengers.
    Advances in enzyme regulation, 1996, Volume: 36

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Atropine; Calcium; Egtazic Acid; Enzyme Inhibitors; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Maleimides; Neuroblastoma; Nickel; Phosphatidylinositols; Protein Kinase Inhibitors; Signal Transduction; Staurosporine; Tumor Cells, Cultured

1996
Protein kinase C modulator effects on parathyroid hormone-induced intracellular calcium and morphologic changes in UMR 106-H5 osteoblastic cells.
    Journal of cellular biochemistry, 1997, Volume: 65, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Animals; Calcium; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Inositol 1,4,5-Trisphosphate; Naphthalenes; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Tumor Cells, Cultured

1997
Experimental esophagitis affects intracellular calcium stores in the cat lower esophageal sphincter.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Analysis of Variance; Animals; Benzimidazoles; Calcium; Calmodulin; Cats; Diglycerides; Esophagitis; Esophagogastric Junction; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Thapsigargin; Time Factors

1997
Secreted form of beta-amyloid precursor protein activates protein kinase C and phospholipase Cgamma1 in cultured embryonic rat neocortical cells.
    Brain research. Molecular brain research, 1998, Volume: 53, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amyloid beta-Protein Precursor; Animals; Cells, Cultured; Cytosol; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Neocortex; Neurons; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Recombinant Proteins; Signal Transduction; Type C Phospholipases

1998
Signal transduction pathways mediating CCK-induced gallbladder muscle contraction.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzimidazoles; Calcium; Calmodulin; Cats; Cell Membrane; Cholecystokinin; Diglycerides; Egtazic Acid; Female; Gallbladder; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoenzymes; Male; Muscle Contraction; Muscle, Smooth; Pertussis Toxin; Phospholipase C beta; Potassium Chloride; Signal Transduction; Type C Phospholipases; Virulence Factors, Bordetella

1998
Activation of phospholipase C and protein kinase C is required for expression of anthrax lethal toxin cytotoxicity in J774A.1 cells.
    Cellular signalling, 1999, Volume: 11, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antigens, Bacterial; Bacterial Toxins; Cell Death; Cell Line; Inositol 1,4,5-Trisphosphate; Macrophages; Mice; Neomycin; Peptide Hydrolases; Protein Kinase C; Time Factors; Type C Phospholipases

1999
A role of protein kinase C in the regulation of cytosolic phospholipase A(2) in bradykinin-induced PGI(2) synthesis by human vascular endothelial cells.
    Microvascular research, 1999, Volume: 58, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Base Sequence; Bradykinin; Calcium; Cells, Cultured; Cytosol; DNA Primers; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Kinetics; Maleimides; Mutagenesis, Site-Directed; Phospholipases A; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate

1999
Modulation of ICa-L by alpha1-adrenergic stimulation in rat ventricular myocytes.
    Canadian journal of physiology and pharmacology, 2005, Volume: 83, Issue:11

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Calcium; Calcium Channels, L-Type; Enzyme Inhibitors; Heart Ventricles; Inositol 1,4,5-Trisphosphate; Methoxamine; Muscle Cells; Phenylephrine; Prazosin; Propranolol; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Ventricular Function

2005