1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with glycine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (52.63) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duman, RS; Hayward, MD; Nestler, EJ; Tallman, JF; Vaccarino, FM | 1 |
| Akaike, N; Kawamoto, I; Nabekura, J | 1 |
| Krieger, C; Lanius, RA; Shaw, CA; Wagey, R | 1 |
| Bossemeyer, D; Engh, RA; Girod, A; Huber, R; Kinzel, V | 1 |
| Burke, JP; Hablitz, JJ | 1 |
| Churchill, D; Jarvis, CR; Lu, WY; MacDonald, JF; MacVicar, BA; Plant, JR; Xiong, ZG | 1 |
| Copenhagen, DR; Dixon, DB | 1 |
| Krnjević, K; Liu, PL; McArdle, JJ; Ren, J; Ye, JH | 1 |
| Kobayashi, K; Manabe, T; Takahashi, T | 1 |
| Collingridge, GL; Kilpatrick, IC; Palmer, MJ; Schnabel, R | 1 |
| Dong, XP; Wang, DS; Xu, TL | 1 |
| Hermans, E; Maloteaux, JM; Najimi, M; Page, G; Peeters, M | 1 |
| Johnson, SW; Shen, KZ | 1 |
| Bossemeyer, D; Breitenlechner, C; Engh, RA; Gassel, M; Hidaka, H; Huber, R; Kinzel, V | 1 |
| Baraldi, PG; Borea, PA; Cara, CL; Carrion, MD; Cruz-Lopez, O; Fogli, E; Gessi, S; Moorman, AR; Preti, D; Romagnoli, R; Sacchetto, V; Tabrizi, MA | 1 |
| Chambers, LJ; Michel, AD; Walter, DS | 1 |
| Clay, WC; Condreay, JP; Hall, M; Holbrook, J; Livermore, D; Michel, AD; Ng, SW; Roman, S; Senger, S; Thompson, K | 1 |
| Greggio, E; Longo, F; Morari, M; Russo, I; Shimshek, DR | 1 |
| Chen, L; Du, Y; Huang, S; Men, C; Qi, M; Wang, Z; Wu, C; Zhou, L | 1 |
19 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and glycine
| Article | Year |
|---|---|
Differential induction of immediate early genes by excitatory amino acid receptor types in primary cultures of cortical and striatal neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Blotting, Northern; Cells, Cultured; Cerebral Cortex; Corpus Striatum; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation; Genes, fos; Genes, jun; Genes, Regulator; Glutamates; Glutamic Acid; Glycine; Immediate-Early Proteins; Isoquinolines; Neurons; Piperazines; Protein Kinase Inhibitors; Proto-Oncogenes; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Sulfonamides; Transcription Factors | 1992 |
Developmental change in voltage dependency of NMDA receptor-mediated response in nucleus tractus solitarii neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Electrophysiology; Female; Glycine; In Vitro Techniques; Isoquinolines; Magnesium; Membrane Potentials; Neurons; Phorbol Esters; Piperazines; Pregnancy; Protein Kinase C; Rats; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 1994 |
Characterization, distribution, and protein kinase C-mediated regulation of [35S]glutathione binding sites in mouse and human spinal cord.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Aged, 80 and over; Animals; Binding Sites; Enzyme Activation; Glutathione; Glycine; Humans; Isoquinolines; Mice; Mice, Inbred C57BL; Middle Aged; Phorbol Esters; Piperazines; Protein Kinase C; Receptors, Peptide; Spinal Cord; Sulfur Radioisotopes | 1994 |
Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Binding Sites; Casein Kinase II; Casein Kinases; Cattle; Crystallography, X-Ray; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Glycine; Isoquinolines; Myosin-Light-Chain Kinase; Protein Conformation; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Sulfonamides | 1996 |
G-protein activation by metabotropic glutamate receptors reduces spike frequency adaptation in neocortical neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adult; Alanine; Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Enzyme Inhibitors; Frontal Lobe; Glycine; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Isoquinolines; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Staurosporine; Sulfonamides; Thionucleotides | 1996 |
Neurotrophin modulation of NMDA receptors in cultured murine and isolated rat neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Corpus Striatum; Dynorphins; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Ion Channel Gating; Kynurenic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Nerve Growth Factors; Neurons; Neurotrophin 3; Protein Kinase Inhibitors; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1997 |
Metabotropic glutamate receptor-mediated suppression of an inward rectifier current is linked via a cGMP cascade.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Aminobutyrates; Animals; Atrial Natriuretic Factor; Benzoates; Cyclic GMP; Enzyme Inhibitors; Glutamic Acid; Glycine; Ictaluridae; Ion Channel Gating; Isoquinolines; Models, Neurological; Patch-Clamp Techniques; Photoreceptor Cells; Potassium Channels; Receptors, Metabotropic Glutamate; Second Messenger Systems; Thionucleotides | 1997 |
Cocaine decreases the glycine-induced Cl- current of acutely dissociated rat hippocampal neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Anesthetics, Local; Animals; Benzophenanthridines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Chloride Channels; Cocaine; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; Glycine Agents; Hippocampus; Isoquinolines; Kainic Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenanthridines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Strychnine; Sulfonamides; Tetrodotoxin | 1999 |
Calcium-dependent mechanisms involved in presynaptic long-term depression at the hippocampal mossy fibre-CA3 synapse.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anticonvulsants; Calcium; Chelating Agents; Cyclopropanes; Egtazic Acid; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glycine; Long-Term Potentiation; Magnesium; Mice; Mice, Inbred ICR; Mossy Fibers, Hippocampal; Neural Inhibition; Neuronal Plasticity; Phosphorylation; Presynaptic Terminals; Receptors, Metabotropic Glutamate | 1999 |
A CaMKII inhibitor, KN-62, facilitates DHPG-induced LTD in the CA1 region of the hippocampus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzoates; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Depression, Chemical; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; In Vitro Techniques; Methoxyhydroxyphenylglycol; Neuronal Plasticity; Rats; Rats, Wistar; Signal Transduction; Synaptic Transmission | 1999 |
N-methyl-D-aspartate enhancement of the glycine response in the rat sacral dorsal commissural neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Chloride Channels; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Kinetics; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Spinal Cord | 2000 |
Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Indoles; Isoquinolines; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Phosphorylation; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Staurosporine; Sulfonamides; Synaptosomes; Tetradecanoylphorbol Acetate | 2001 |
Group II metabotropic glutamate receptor modulation of excitatory transmission in rat subthalamic nucleus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclase Inhibitors; Amino Acids; Amino Acids, Dicarboxylic; Animals; Colforsin; Cyclopropanes; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glycine; Imines; In Vitro Techniques; Isoquinolines; Male; Picrotoxin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Subthalamic Nucleus; Sulfonamides; Synaptic Transmission; Tetradecanoylphorbol Acetate; Xanthenes | 2003 |
Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amides; Amino Acid Sequence; Animals; Binding Sites; Cattle; Cell Adhesion; Crystallography, X-Ray; Cyclic AMP-Dependent Protein Kinases; Electrons; Enzyme Inhibitors; Escherichia coli; Glycine; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyridines; Recombinant Proteins; Sequence Homology, Amino Acid | 2003 |
From tyrosine to glycine: synthesis and biological activity of potent antagonists of the purinergic P2X7 receptor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; beta-Alanine; Calcium; Cell Line; Cell Membrane; Cell Membrane Permeability; Ethidium; Fluorescent Dyes; Glycine; Humans; Isoquinolines; Naphthalenes; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2X7; Recombinant Proteins; Structure-Activity Relationship; Sulfonamides; Sulfones; Tyrosine | 2007 |
Negative and positive allosteric modulators of the P2X(7) receptor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Allosteric Regulation; Animals; Binding Sites; Cell Line; Dose-Response Relationship, Drug; Ethidium; Glycine; Humans; Molecular Structure; Piperazines; Protein Conformation; Pyridoxal Phosphate; Quinolines; Radioligand Assay; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Recombinant Proteins; Species Specificity; Time Factors; Transfection; Vanadates | 2008 |
Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Cell Line; Cloning, Molecular; Dose-Response Relationship, Drug; Glycine; Humans; Imidazoles; Molecular Sequence Data; Mutagenesis, Site-Directed; Piperazines; Plasmids; Polymorphism, Single Nucleotide; Protein Binding; Protein Structure, Tertiary; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridines; Pyridoxal Phosphate; Radioligand Assay; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Sequence Alignment; Species Specificity; Transfection | 2008 |
Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aging; Analysis of Variance; Animals; Brain; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycine; Humans; Hyperkinesis; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; NIH 3T3 Cells; Protein Serine-Threonine Kinases; Serine; Time Factors | 2014 |
Transient Receptor Potential Vanilloid 4 Activation-Induced Increase in Glycine-Activated Current in Mouse Hippocampal Pyramidal Neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Evoked Potentials; Glycine; Hippocampus; Leucine; Mice; Mice, Inbred ICR; Morpholines; Patch-Clamp Techniques; Protein Kinase C; Pyramidal Cells; Pyrroles; Receptors, Glycine; Signal Transduction; Strychnine; Sulfonamides; TRPV Cation Channels | 2018 |