Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and glyburide

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with glyburide in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Ashcroft, SJ; Niki, I1
Davidson, MB; Furman, A; Molnar, IG; Yamaguchi, D1
Black, SC; Chi, L; Fagbemi, SO; Friedrichs, GS; Lucchesi, BR1
Cha, T; Fujioka, Y; Fukuda, M; Ikegami, H; Kawaguchi, Y; Noma, Y; Ogihara, T; Shima, K; Tahara, Y; Yamato, E1
Katsube, Y; Sperelakis, N; Sunagawa, M; Yokoshiki, H1
Höfler, S; Mühl, H; Pfeilschifter, J1

Other Studies

7 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and glyburide

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Possible involvement of protein phosphorylation in the regulation of the sulphonylurea receptor of a pancreatic beta-cell line, HIT T15.
    Biochimica et biophysica acta, 1991, Dec-03, Volume: 1133, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Cell Line; Cell Membrane; Colforsin; Diazoxide; Glyburide; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Phosphorylation; Piperazines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase Inhibitors; Proteins; Receptors, Drug; Rubidium; Sulfonylurea Receptors; Tetradecanoylphorbol Acetate

1991
Glyburide-stimulated glucose transport in cultured muscle cells via protein kinase C-mediated pathway requiring new protein synthesis.
    Diabetes, 1991, Volume: 40, Issue:11

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Aminoquinolines; Animals; Biological Transport; Cells, Cultured; Cycloheximide; Glucose; Glyburide; Glycogen; Islets of Langerhans; Isoquinolines; Muscles; Piperazines; Potassium Channels; Protein Kinase C; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate; Verapamil

1991
Phorbol ester-induced ventricular fibrillation in the Langendorff-perfused rabbit heart: antagonism by staurosporine and glibenclamide.
    Journal of molecular and cellular cardiology, 1993, Volume: 25, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Diglycerides; Glyburide; Guanidines; Isoquinolines; Perfusion; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pinacidil; Piperazines; Protein Kinase C; Rabbits; Staurosporine; Ventricular Fibrillation

1993
Cellular mechanism of glyburide-induced insulin gene expression in isolated rat islets.
    Biochemical and biophysical research communications, 1993, Dec-15, Volume: 197, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; DNA Probes; Gene Expression; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Kinetics; Male; Piperazines; Proinsulin; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger

1993
Levosimendan, a novel Ca2+ sensitizer, activates the glibenclamide-sensitive K+ channel in rat arterial myocytes.
    European journal of pharmacology, 1997, Aug-27, Volume: 333, Issue:2-3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Charybdotoxin; Enzyme Inhibitors; Female; Glyburide; Hydrazones; Hypoglycemic Agents; Male; Membrane Potentials; Mesenteric Arteries; Patch-Clamp Techniques; Potassium Channels; Pyridazines; Rats; Simendan; Vasodilator Agents

1997
Inhibition of lipopolysaccharide/ATP-induced release of interleukin-18 by KN-62 and glyburide.
    European journal of pharmacology, 2003, Dec-15, Volume: 482, Issue:1-3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Glyburide; Humans; Interleukin-18; Leukocytes, Mononuclear; Lipopolysaccharides

2003