1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with glutamic acid in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 22 (59.46) | 18.2507 |
| 2000's | 9 (24.32) | 29.6817 |
| 2010's | 6 (16.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castrén, E; Hartikka, J; Lindholm, D; Thoenen, H; Zafra, F | 1 |
| Duman, RS; Hayward, MD; Nestler, EJ; Tallman, JF; Vaccarino, FM | 1 |
| Fujii, T; Kuraishi, Y; Satoh, M; Ueda, M | 1 |
| Aragón, C; Casado, M; Giménez, C; Zafra, F | 1 |
| Okada, Y; Sakurai, T; Shibata, Y; Tomita, H | 1 |
| Churcher, Y; Gomperts, BD | 1 |
| Coderre, TJ; Yashpal, K | 1 |
| Felipo, V; Grisolía, S; Miñana, MD | 1 |
| Gerdes, W; Louis, JC; Magal, E; Seifert, W | 1 |
| Hirai, H; Okada, Y | 1 |
| Maguire, G; Werblin, F | 1 |
| Onozuka, M; Watanabe, K | 1 |
| Pearson, HA; Sihra, TS | 1 |
| Holtsberg, FW; Keller, JN; Mattson, MP; Steiner, MR; Steiner, SM | 1 |
| Copenhagen, DR; Dixon, DB | 1 |
| Braun, C; Plattner, H; Purvee, J; Van Houten, JL; Yang, WQ | 1 |
| Feng, YZ; Ho, IK; Tokuyama, S; Wakabayashi, H; Zhu, H | 1 |
| Chiu, LM; Guarneros, A; Peña, F; Sitges, M | 1 |
| Kasahara, J; Sugiyama, H | 1 |
| Best, JD; Hastings, MH; McNulty, S; Schurov, IL; Sloper, PJ | 1 |
| Chen, YZ; Xing, BR; Zhu, BG | 1 |
| Glazner, GW; Mattson, MP | 1 |
| Kubo, Y; Miyashita, T | 1 |
| Gao, C; Zhang, GY | 1 |
| Nakajima, Y; Nakanishi, S; Shinohara, Y | 1 |
| Dohovics, R; Hermann, A; Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| Isenoumi, K; Kitaoka, Y; Kobayashi, S; Kumai, T; Kuribayashi, K; Lam, TT; Motoki, M; Munemasa, Y; Ueno, S | 1 |
| Frerking, M; Partovi, D | 1 |
| Hara, H; Iwama, T; Kotani, Y; Nakajima, Y; Nakashima, S; Shimazawa, M; Yamashita, K; Yoshimura, S | 1 |
| Hjelmstad, GO; Warrier, A | 1 |
| Chen, J; Cheng, Z; Guo, L; He, Z; Huang, L; Li, H; Li, Q | 1 |
| Huang, WJ; Lin, TY; Lu, CW; Wang, SJ | 1 |
| Beart, PM; Bischof, L; Broberg, BV; Lau, CL; O'Shea, RD | 1 |
| Barcomb, K; Bayer, KU; Coultrap, SJ | 1 |
| Artalejo, AR; Bustillo, D; Marín-García, P; Miras-Portugal, MT; Olivos-Oré, LA; Sánchez-Nogueiro, J | 1 |
| Holloway, AL; Hong-Routson, S; Piao, CS; Wainwright, MS | 1 |
| Fu, R; Li, W; Matthew, L; Mei, Q; Wu, L; Wu, W; Ye, JH; Zhou, Z; Zuo, Q; Zuo, W | 1 |
37 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and glutamic acid
| Article | Year |
|---|---|
Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Glutamates; Glutamic Acid; Growth Substances; Hippocampus; Ionomycin; Isoquinolines; Kainic Acid; Kinetics; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Nifedipine; Norepinephrine; Piperazines; Potassium; Protein Kinase Inhibitors; Quisqualic Acid; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Differential induction of immediate early genes by excitatory amino acid receptor types in primary cultures of cortical and striatal neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Blotting, Northern; Cells, Cultured; Cerebral Cortex; Corpus Striatum; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation; Genes, fos; Genes, jun; Genes, Regulator; Glutamates; Glutamic Acid; Glycine; Immediate-Early Proteins; Isoquinolines; Neurons; Piperazines; Protein Kinase Inhibitors; Proto-Oncogenes; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Sulfonamides; Transcription Factors | 1992 |
Bifemelane enhances high K(+)-evoked release of glutamate from mossy fiber synaptosomes of guinea-pig hippocampus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antidepressive Agents; Benzhydryl Compounds; Binding Sites; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Isoquinolines; Male; Piperazines; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Synaptosomes | 1992 |
Activation of high-affinity uptake of glutamate by phorbol esters in primary glial cell cultures.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Binding, Competitive; Calcimycin; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Glutamates; Glutamic Acid; Isoquinolines; Kinetics; Neuroglia; Neurons; Piperazines; Tetradecanoylphorbol Acetate | 1991 |
Involvement of a protein kinase C-dependent process in long-term potentiation formation in guinea pig superior colliculus slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Electric Stimulation; Enzyme Activation; Evoked Potentials; Glutamates; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Isoquinolines; Melitten; Piperazines; Polymyxin B; Protein Kinase C; Superior Colliculi; Tetany; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
ATP-dependent and ATP-independent pathways of exocytosis revealed by interchanging glutamate and chloride as the major anion in permeabilized mast cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amino Acid Sequence; Animals; Anions; beta-N-Acetylhexosaminidases; Calcium; Cations; Chlorides; Exocytosis; Glutamates; Glutamic Acid; Glyceryl Ethers; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoquinolines; Male; Mast Cells; Molecular Sequence Data; Peptide Fragments; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Secretory Rate; Signal Transduction | 1990 |
Intracellular messengers contributing to persistent nociception and hyperalgesia induced by L-glutamate and substance P in the rat formalin pain model.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arginine; Dexamethasone; Formaldehyde; Glutamic Acid; Hyperalgesia; Injections, Spinal; Isoquinolines; Male; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain; Pain Measurement; Pain Threshold; Piperazines; Protein Kinase C; Rats; Reflex; Substance P | 1994 |
Inhibitors of protein kinase C prevent the toxicity of glutamate in primary neuronal cultures.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cell Death; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Isoquinolines; Kinetics; Naphthalenes; Neurons; Neurotoxins; Piperazines; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Wistar | 1993 |
Survival-promoting and protein kinase C-regulating roles of basic FGF for hippocampal neurons exposed to phorbol ester, glutamate and ischaemia-like conditions.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Brain Ischemia; Cell Survival; Cells, Cultured; Fibroblast Growth Factor 2; Glutamates; Glutamic Acid; Hippocampus; Isoquinolines; Molecular Sequence Data; Neurons; Piperazines; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1993 |
Adenosine facilitates glutamate release in a protein kinase-dependent manner in superior colliculus slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Calcium; Electric Stimulation; Electrophysiology; Glutamates; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Isoquinolines; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Sulfonamides; Superior Colliculi; Tetrodotoxin | 1994 |
Dopamine enhances a glutamate-gated ionic current in OFF bipolar cells of the tiger salamander retina.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Ambystoma; Animals; Benzazepines; Dendrites; Dopamine; Glutamic Acid; GTP-Binding Proteins; In Vitro Techniques; Ion Channel Gating; Isoquinolines; Kainic Acid; Piperazines; Protein Kinase Inhibitors; Receptors, Glutamate; Retina; Synaptic Transmission; Up-Regulation | 1994 |
Glutamate elicits an outward K+ current which is normally suppressed by a Ca2+/calmodulin-dependent protein kinase II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alkaloids; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cholera Toxin; Dose-Response Relationship, Drug; Ganglia, Invertebrate; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kynurenic Acid; Membrane Potentials; Neurons; Pertussis Toxin; Piperazines; Potassium Channels; Protein Kinase Inhibitors; Snails; Staurosporine; Sulfonamides; Time Factors; Virulence Factors, Bordetella | 1994 |
Ca/calmodulin-dependent kinase II inhibitor KN62 attenuates glutamate release by inhibiting voltage-dependent Ca(2+)-channels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium Channels; Calmodulin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Isoquinolines; Piperazines; Protein Kinases; Rats; Rats, Inbred Strains; Synaptosomes; Time Factors | 1995 |
Lysophosphatidic acid-induced proliferation-related signals in astrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Astrocytes; Brain; Calcium; Cell Division; Cells, Cultured; DNA; Fibroblast Growth Factor 2; Glutamic Acid; Kinetics; Lipid Peroxidation; Lysophosphatidylcholines; Lysophospholipids; Pertussis Toxin; Phosphatidic Acids; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiobarbituric Acid Reactive Substances; Virulence Factors, Bordetella | 1997 |
Metabotropic glutamate receptor-mediated suppression of an inward rectifier current is linked via a cGMP cascade.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Aminobutyrates; Animals; Atrial Natriuretic Factor; Benzoates; Cyclic GMP; Enzyme Inhibitors; Glutamic Acid; Glycine; Ictaluridae; Ion Channel Gating; Isoquinolines; Models, Neurological; Patch-Clamp Techniques; Photoreceptor Cells; Potassium Channels; Receptors, Metabotropic Glutamate; Second Messenger Systems; Thionucleotides | 1997 |
Cyclic nucleotides in glutamate chemosensory signal transduction of Paramecium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Ammonium Chloride; Animals; Chemotactic Factors; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; Glutamic Acid; Inosine Monophosphate; Intracellular Fluid; Isoquinolines; Paramecium tetraurelia; Potassium Acetate; Quisqualic Acid; Second Messenger Systems; Signal Transduction | 1997 |
The role of glutamate in the locus coeruleus during opioid withdrawal and effects of H-7, a protein kinase inhibitor, on the action of glutamate in rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Butorphanol; Glutamic Acid; Infusions, Parenteral; Locus Coeruleus; Male; Microdialysis; Morphine Dependence; Motor Activity; Naloxone; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substance-Related Disorders | 1998 |
Study on the possible involvement of protein kinases in the modulation of brain presynaptic sodium channels; comparison with calcium channels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain; Calcium; Calcium Channels; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Okadaic Acid; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Sodium; Sodium Channels; Synaptosomes; Tetrodotoxin; Veratridine | 1998 |
Modulation of glutamate sensitivities by inhibitors of a protein kinase and a protein phosphatase in cultured rat Purkinje cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Iontophoresis; Marine Toxins; Nerve Tissue Proteins; Oxazoles; Protein Tyrosine Phosphatases; Purkinje Cells; Rats; Receptors, AMPA; Sulfonamides | 1998 |
Glutamatergic induction of CREB phosphorylation and Fos expression in primary cultures of the suprachiasmatic hypothalamus in vitro is mediated by co-ordinate activity of NMDA and non-NMDA receptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cricetinae; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Gene Expression; Genes, fos; Glutamic Acid; Kainic Acid; Male; Mesocricetus; N-Methylaspartate; Phosphorylation; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus | 1999 |
Effect of calcium on the uptake of glutamate by synaptosomes: possible involvement of two different mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cerebral Cortex; Chelating Agents; Egtazic Acid; Electrophysiology; Enzyme Inhibitors; Glutamic Acid; Male; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Synaptosomes; Tetrodotoxin; Trifluoperazine | 1999 |
Differential effects of BDNF, ADNF9, and TNFalpha on levels of NMDA receptor subunits, calcium homeostasis, and neuronal vulnerability to excitotoxicity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Brain; Brain-Derived Neurotrophic Factor; Calcium; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Embryo, Mammalian; Glutamic Acid; Homeostasis; Kinetics; Necrosis; Nerve Tissue Proteins; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tumor Necrosis Factor-alpha | 2000 |
Extracellular Ca2+ sensitivity of mGluR1alpha induces an increase in the basal cAMP level by direct coupling with Gs protein in transfected CHO cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Calcium; Cell Size; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Fluorescent Dyes; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Isoquinolines; MAP Kinase Signaling System; Protein Kinase C; Receptors, Metabotropic Glutamate; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases | 2000 |
KN-62 provides neuroprotection against glutamate-induced excitotoxicity in neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Survival; Cells, Cultured; Cerebral Cortex; Female; Glutamic Acid; Neurons; Neuroprotective Agents; Phosphorylation; Rats; Rats, Sprague-Dawley | 1999 |
Glutamate induces focal adhesion kinase tyrosine phosphorylation and actin rearrangement in heterologous mGluR1-expressing CHO cells via calcium/calmodulin signaling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cricetinae; Cytoskeleton; Edetic Acid; Egtazic Acid; Enzyme Inhibitors; Estrenes; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Glutamic Acid; Indoles; Kinetics; Maleimides; Phosphorylation; Protein-Tyrosine Kinases; Pyrrolidinones; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Transfection; Type C Phospholipases | 2001 |
Regulation of glutamatergic neurotransmission in the striatum by presynaptic adenylyl cyclase-dependent processes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bucladesine; Calcium; Calmodulin; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Feedback; Female; Glutamic Acid; Imidazoles; Imines; Isoenzymes; Isoproterenol; Isoquinolines; Kainic Acid; Male; Mice; N-Methylaspartate; Nerve Tissue Proteins; Propranolol; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Presynaptic; Second Messenger Systems; Sulfonamides; Synaptic Transmission; Trifluoperazine | 2003 |
Involvement of RhoA and possible neuroprotective effect of fasudil, a Rho kinase inhibitor, in NMDA-induced neurotoxicity in the rat retina.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Count; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Degeneration; Retinal Ganglion Cells; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Thy-1 Antigens; Up-Regulation | 2004 |
Presynaptic inhibition by kainate receptors converges mechanistically with presynaptic inhibition by adenosine and GABAB receptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Alanine; Animals; Baclofen; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Agonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Naphthalenes; Neuromuscular Depolarizing Agents; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Kainic Acid; Receptors, Presynaptic; Thymine | 2006 |
Fasudil, a Rho kinase (ROCK) inhibitor, protects against ischemic neuronal damage in vitro and in vivo by acting directly on neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain Ischemia; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Glutamic Acid; Hypoxia; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Mice; Neurofilament Proteins; Neurons; Neuroprotective Agents; PC12 Cells; Protein Serine-Threonine Kinases; Rats; rho-Associated Kinases; Time Factors | 2007 |
Protein kinase inhibitors reduce GABA but not glutamate release in the nucleus accumbens.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Nucleus Accumbens; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley | 2007 |
Inhibition of intracellular Ca2+ release by a Rho-kinase inhibitor for the treatment of ischemic damage in primary cultured rat hippocampal neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Hippocampus; Hypoxia; Intracellular Space; Ischemia; Neurons; Potassium Chloride; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; rho-Associated Kinases | 2009 |
Osthole or imperatorin-mediated facilitation of glutamate release is associated with a synaptic vesicle mobilization in rat hippocampal glutamatergic nerve endings.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Central Nervous System Agents; Coumarins; Cytochalasin D; Enzyme Inhibitors; Furocoumarins; Glutamic Acid; Hippocampus; Ionomycin; Male; Neurons; Potassium Chloride; Rats; Rats, Sprague-Dawley; Synapsins; Synaptic Vesicles | 2010 |
The Rho kinase inhibitor Fasudil up-regulates astrocytic glutamate transport subsequent to actin remodelling in murine cultured astrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Aspartic Acid; Astrocytes; Biological Transport; Cells, Cultured; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glial Fibrillary Acidic Protein; Glutamic Acid; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Prosencephalon; rho-Associated Kinases; Up-Regulation | 2011 |
Enzymatic activity of CaMKII is not required for its interaction with the glutamate receptor subunit GluN2B.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Female; Glutamic Acid; HEK293 Cells; Humans; Male; Neurons; Phosphorylation; Protein Binding; Protein Subunits; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Staurosporine; Synapses | 2013 |
Subcellular distribution and early signalling events of P2X7 receptors from mouse cerebellar granule neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Cerebellum; Fura-2; Glutamic Acid; Mice; Mice, Inbred C57BL; Neurons; Purinergic P2X Receptor Antagonists; Pyridines; Receptors, Purinergic P2X7; Tetrazoles | 2014 |
Depression following traumatic brain injury in mice is associated with down-regulation of hippocampal astrocyte glutamate transporters by thrombin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Astrocytes; Behavior, Animal; Blood-Brain Barrier; Brain Injuries, Traumatic; Depression; Down-Regulation; Enzyme Inhibitors; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Male; Mice; Receptor, PAR-1; rho-Associated Kinases; Thrombin; Vesicular Glutamate Transport Proteins | 2019 |
Adaptation in 5-HT
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Central Nervous System Depressants; Enzyme Inhibitors; Ethanol; Excitatory Postsynaptic Potentials; Glutamic Acid; Habenula; Neurons; Nociception; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT2; RNA, Messenger; Serotonin 5-HT2 Receptor Antagonists; Substance Withdrawal Syndrome | 2019 |