1-(5-isoquinolinesulfonyl)-2-methylpiperazine and fomesafen

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with fomesafen in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's5 (83.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coderre, TJ; Yashpal, K1
Hara, M; Noda, A; Suzuki, Y; Takagi, T; Takayasu, M; Watanabe, K; Yoshida, J1
Asano, T; Ikegaki, I; Satoh, S; Toshima, Y1
Honda, M; Ishikawa, T; Nakayama, K; Suzuki, M1
Büyükafşar, K; Inan, S1
Holowatz, LA; Jennings, JD; Kenney, WL; Lang, JA1

Other Studies

6 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and fomesafen

ArticleYear
Intracellular messengers contributing to persistent nociception and hyperalgesia induced by L-glutamate and substance P in the rat formalin pain model.
    The European journal of neuroscience, 1994, Aug-01, Volume: 6, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arginine; Dexamethasone; Formaldehyde; Glutamic Acid; Hyperalgesia; Injections, Spinal; Isoquinolines; Male; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain; Pain Measurement; Pain Threshold; Piperazines; Protein Kinase C; Rats; Reflex; Substance P

1994
Protein kinase inhibition by fasudil hydrochloride promotes neurological recovery after spinal cord injury in rats.
    Journal of neurosurgery, 2000, Volume: 93, Issue:1 Suppl

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analysis of Variance; Animals; Behavior, Animal; Contusions; Enzyme Inhibitors; Female; Follow-Up Studies; Injections, Intraperitoneal; Injections, Intravenous; Laser-Doppler Flowmetry; Leukocytes; Methylprednisolone; Motor Activity; Neuroprotective Agents; Neutrophils; Peroxidase; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Recovery of Function; Reflex; Regional Blood Flow; Spinal Cord; Spinal Cord Injuries; Statistics, Nonparametric

2000
A new model of cerebral microthrombosis in rats and the neuroprotective effect of a Rho-kinase inhibitor.
    Stroke, 2000, Volume: 31, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain Infarction; Carotid Artery, Internal; Cerebral Cortex; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hippocampus; Intracellular Signaling Peptides and Proteins; Lauric Acids; Male; Microscopy, Electron; Neurologic Examination; Neuroprotective Agents; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Reflex; rho-Associated Kinases; Staining and Labeling; Stroke; Thalamus

2000
Role of alpha2C-adrenoceptors in the reduction of skin blood flow induced by local cooling in mice.
    British journal of pharmacology, 2007, Volume: 152, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenalectomy; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amides; Anesthetics, Local; Animals; Blood Pressure; Blood Vessels; Body Temperature Regulation; Clonidine; Cold Temperature; Heart Rate; Intracellular Signaling Peptides and Proteins; Isoquinolines; Laser-Doppler Flowmetry; Male; Mice; Naphthyridines; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Quinolizines; Receptors, Adrenergic, alpha-2; Reflex; Regional Blood Flow; rho-Associated Kinases; Skin; Skin Temperature; Sympathetic Nervous System; Tetrodotoxin; Vasoconstriction

2007
Antiepileptic effects of two Rho-kinase inhibitors, Y-27632 and fasudil, in mice.
    British journal of pharmacology, 2008, Volume: 155, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Anticonvulsants; Blotting, Western; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Kindling, Neurologic; Male; Mice; Motor Activity; Pentylenetetrazole; Protein Kinase Inhibitors; Protein Transport; Pyridines; Reflex; rho-Associated Kinases; Seizures

2008
Reflex vasoconstriction in aged human skin increasingly relies on Rho kinase-dependent mechanisms during whole body cooling.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Age Factors; Aged; Aging; Blood Flow Velocity; Blood Pressure; Blood Vessels; Body Temperature Regulation; Cold Temperature; Female; Forearm; Humans; Laser-Doppler Flowmetry; Male; Microdialysis; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; Protein Kinase Inhibitors; Reflex; Regional Blood Flow; rho-Associated Kinases; Skin; Vasoconstriction; Vasodilator Agents; Young Adult

2009