1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with epidermal growth factor in 41 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (4.88) | 18.7374 |
1990's | 34 (82.93) | 18.2507 |
2000's | 5 (12.20) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Kobuchi, H; Li, MJ; Matsuno, T; Utsumi, K; Yasuda, T | 1 |
Kobayashi, T | 1 |
Ikeda, K; Kikuchi, T; Matsumoto, T; Morimoto, K; Nakano, T; Ogata, E; Okazaki, R; Sakamoto, A; Urakawa, K | 1 |
Joyce, NC; Meklir, B | 1 |
Hamm, LL; Herndon, J; Vehaskari, VM | 1 |
Cao, XM; Guy, GR; Sukhatme, VP; Tan, YH | 1 |
Albright, CD; Fontana, JA; Grimley, PM; Jones, RT; Keenan, KP; Resau, JH | 1 |
Moore, JJ; Moore, RM; Vander Kooy, D | 1 |
Deuel, TF; Shawver, LK | 1 |
Emoto, T; Hattori, Y; Hiraiwa, M; Kasai, K; Kuroda, H; Shimoda, S; Yamazaki, A | 1 |
Teitelbaum, I | 1 |
Fujiwara, K; Hirata, K | 1 |
Aizu, E; Kato, R; Nakadate, T; Nishikawa, K; Yamamoto, S | 1 |
Gross, JL; Morrison, RS; Moskal, JR | 1 |
Eling, TE; Hamasaki, Y | 1 |
Goishi, K; Higashiyama, S; Ishikawa, M; Klagsbrun, M; Mekada, E; Nakano, N; Taniguchi, N; Umata, T | 1 |
Boccone, L; Maiese, K | 1 |
Maiese, K | 1 |
Fusamoto, H; Hayashi, N; Horimoto, M; Ito, T; Kamada, T; Kaneko, A; Kasahara, A; Sasaki, Y; Tanaka, Y | 1 |
Ando, Y; Jensen, PJ; Lazarus, GS | 1 |
Boniece, IR; Wagner, JA | 1 |
Harada, H; Motomura, A; Suketa, Y; Suzuki, S; Tai, H | 1 |
Hashimoto, Y; Iizuka, H; Ishida-Yamamoto, A; Takahashi, H | 1 |
DelValle, J; Osburn, J; Wang, L; Wilson, EJ | 1 |
Koseki, N; Sato, H; Yoshizato, K | 1 |
Amar, L; Forest, N; Martin, N; Oboeuf, M; Shabana, AH | 1 |
Hidaka, H; Niki, I; Yasui, K | 1 |
Aguirre Ghiso, JA; Alonso, DF; Bal de Kier Joffé, E; Farías, EF | 1 |
Atsumi, T; Hosoi, K; Kurihara, K; Shioda, Y; Sugita, K; Ueha, T | 1 |
Higashiyama, S; Ito, N; Kawata, S; Kiso, S; Matsuzawa, Y; Nakagawa, T; Tamura, S; Taniguchi, N; Tsushima, H | 1 |
Aguirre Ghiso, JA; Bal de Kier Joffé, E; Ladeda, V | 1 |
Carpio, LC; Dziak, R | 1 |
Forest, N; Goldberg, M; Lecolle, S; Shabana, AH | 1 |
Hunzicker-Dunn, M; Lamm, ML; Rajagopalan-Gupta, RM | 1 |
Cao, X; Jain, N; Kee, WH; Li, W; Zhang, T | 1 |
Takigawa, M; Wakita, H | 1 |
Jope, RS; Song, L; Zhang, L | 1 |
Lunn, JA; Rozengurt, E; Walsh, JH; Wong, H | 1 |
Cui, WR; Li, A; Lin, JS; Wang, JL; Wu, BW; Wu, Y; Yuan, SY | 1 |
Bai, XD; Fu, XB; Sun, TZ; Zhang, Q | 1 |
Geng, CZ; Liu, YP; Ma, L; Wang, JL; Xing, LX; Zhang, XH | 1 |
41 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and epidermal growth factor
Article | Year |
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Inhibition of neutrophil priming and tyrosyl phosphorylation by cepharanthine, a nonsteroidal antiinflammatory drug.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Annexin A1; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Epidermal Growth Factor; Granulocyte Colony-Stimulating Factor; Humans; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Phosphorylation; Piperazines; Protein-Tyrosine Kinases; Respiratory Burst; Tumor Necrosis Factor-alpha | 1992 |
[Sulfolipids and glycolipid sulfotransferases in a human renal cell carcinoma cell line].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Carcinoma, Renal Cell; Epidermal Growth Factor; Humans; Isoquinolines; Kidney Neoplasms; Lipid Metabolism; Lipids; Piperazines; Protein Kinase C; Staurosporine; Sulfotransferases; Sulfurtransferases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Transcriptional activation of c-fos and c-jun protooncogenes by serum growth factors in osteoblast-like MC3T3-E1 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Cell Differentiation; Cycloheximide; Dactinomycin; Epidermal Growth Factor; Fibroblast Growth Factor 2; Gene Expression Regulation; Growth Substances; Insulin-Like Growth Factor I; Isoquinolines; Mice; Osteoblasts; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; RNA, Messenger; Staurosporine; Transforming Growth Factor beta | 1992 |
Protein kinase C activation during corneal endothelial wound repair.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Cell Movement; Cells, Cultured; Endothelium, Corneal; Enzyme Activation; Epidermal Growth Factor; Fluorescent Antibody Technique; Fluorescent Dyes; Isoquinolines; Male; Phalloidine; Piperazines; Protein Kinase C; Rabbits; Rhodamines; Sphingosine; Tetradecanoylphorbol Acetate; Wound Healing | 1992 |
Mechanism of sodium transport inhibition by epidermal growth factor in cortical collecting ducts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Biological Transport, Active; Calcium; Carrier Proteins; Desoxycorticosterone; Epidermal Growth Factor; Indomethacin; Isoquinolines; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Pertussis Toxin; Piperazines; Protein Kinase C; Rabbits; Reference Values; Sodium; Sodium-Hydrogen Exchangers; Virulence Factors, Bordetella | 1991 |
Regulation of the Egr-1 gene by tumor necrosis factor and interferons in primary human fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Blotting, Northern; Blotting, Western; DNA; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; HeLa Cells; Humans; Interferon-gamma; Isoquinolines; Kinetics; Mice; Phosphorylation; Piperazines; RNA, Messenger; Staurosporine; Sulfonamides; Thymidine; Tumor Necrosis Factor-alpha | 1992 |
Cell-to-cell communication: a differential response to TGF-beta in normal and transformed (BEAS-2B) human bronchial epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bronchi; Bronchial Neoplasms; Calmodulin; Cell Communication; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Down-Regulation; Epidermal Growth Factor; Epithelium; Humans; Isoquinolines; Piperazines; Protein Kinase Inhibitors; Sulfonamides; Time Factors; Transforming Growth Factor beta | 1991 |
Protein kinase-C activation is required for oxytocin-induced prostaglandin production in human amnion cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Activation; Epidermal Growth Factor; Female; Humans; Isoquinolines; Oxytocin; Phorbol Esters; Piperazines; Pregnancy; Protein Kinase C; RNA, Messenger; Staurosporine; Time Factors; Type C Phospholipases | 1991 |
Nuclear pp64 is phosphorylated in both serine/threonine and tyrosine through complex pathways regulated by 12-O-tetradecanoylphorbol-13-acetate and platelet-derived growth factor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Dimethyl Sulfoxide; Epidermal Growth Factor; Isoquinolines; Kinetics; Nuclear Proteins; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1990 |
Inhibition by protein kinase-C inhibitor and cycloheximide of phorbol ester- and epidermal growth factor-induced arachidonic acid metabolism in cultured porcine thyroid cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cycloheximide; Dinoprostone; Epidermal Growth Factor; Isoquinolines; Kinetics; Male; Mice; Piperazines; Protein Kinase C; Sulfonamides; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland | 1990 |
Cyclic adenosine monophosphate and diacylglycerol. Mutually inhibitory second messengers in cultured rat inner medullary collecting duct cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Cyclic AMP; Diglycerides; Dinoprostone; Epidermal Growth Factor; Glycerides; In Vitro Techniques; Inositol Phosphates; Isoquinolines; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Piperazines; Protein Kinase Inhibitors; Rats; Signal Transduction; Type C Phospholipases | 1990 |
Possible contribution of protein kinase C activation to priming for DNA synthesis induced by epidermal growth factor with insulin and its inhibition by plasma membrane in primary cultured rat hepatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channel Blockers; Cell Membrane; Cells, Cultured; DNA; DNA Replication; Enzyme Activation; Epidermal Growth Factor; Insulin; Isoquinolines; Liver; Male; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Vasopressins | 1990 |
H-7, a protein kinase C inhibitor, inhibits phorbol ester-caused ornithine decarboxylase induction but fails to inhibit phorbol ester-caused suppression of epidermal growth factor binding in primary cultured mouse epidermal cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Enzyme Induction; Epidermal Growth Factor; Epidermis; Isoquinolines; Mice; Ornithine Decarboxylase; Phosphorylation; Piperazines; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1989 |
Inhibition of protein kinase C activity promotes the neurotrophic action of epidermal and basic fibroblast growth factors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Dendrites; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblast Growth Factors; Isoquinolines; Phorbol Esters; Piperazines; Protein Kinase C; Rats | 1988 |
EGF and TPA stimulate de novo synthesis of PGHS-1 and PGHS-2 through different signal transduction pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Line, Transformed; Cinnamates; Dinoprostone; Enzyme Inhibitors; Epidermal Growth Factor; Epithelium; Isoquinolines; Piperazines; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Trachea | 1995 |
Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acids; Animals; Anti-Bacterial Agents; Cell Membrane; Chlorocebus aethiops; Diphtheria Toxin; DNA; Endosomes; Enzyme Inhibitors; Epidermal Growth Factor; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Isoquinolines; Kinetics; Macrolides; Molecular Weight; Piperazines; Protein Kinase C; Protein Precursors; Protein Processing, Post-Translational; Staurosporine; Tetradecanoylphorbol Acetate; Vero Cells | 1995 |
Neuroprotection by peptide growth factors against anoxia and nitric oxide toxicity requires modulation of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Down-Regulation; Epidermal Growth Factor; Fibroblast Growth Factor 2; Hypoxia, Brain; Isoquinolines; Neurons; Neuroprotective Agents; Nitric Oxide; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley | 1995 |
Protein kinase C modulates the protective ability of peptide growth factors during anoxia.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Death; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; Fibroblast Growth Factor 2; Growth Substances; Hippocampus; Hypoxia, Brain; Isoquinolines; Neurons; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley | 1994 |
Characterization of signaling pathways to Na+/H+ exchanger activation with epidermal growth factor in hepatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium; Calcium-Transporting ATPases; Calmodulin; Cells, Cultured; Epidermal Growth Factor; Genistein; Hydrogen-Ion Concentration; Isoflavones; Isoquinolines; Liver; Male; Phenylephrine; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Activation of protein kinase C inhibits human keratinocyte migration.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Catechols; Cell Movement; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Growth Substances; Humans; Isoquinolines; Keratinocytes; Nitriles; Phorbol Esters; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Tyrphostins | 1993 |
Growth factors protect PC12 cells against ischemia by a mechanism that is independent of PKA, PKC, and protein synthesis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Anisomycin; Cell Hypoxia; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Fibroblast Growth Factor 2; Ischemia; Isoquinolines; Kinetics; Models, Biological; Neoplasm Proteins; Nerve Growth Factors; PC12 Cells; Phosphorylation; Piperazines; Protein Kinase C; Staurosporine; Time Factors | 1993 |
Extracellular ATP-induced regulation of epidermal growth factor signaling in cultured renal LLC-PK1 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Animals; Cell Line; Cell Membrane; Cytosol; Epidermal Growth Factor; ErbB Receptors; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kidney; Kinetics; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Activators of protein kinase C but not of phospholipase C modulate adenylate cyclase-responses of normal pig epidermis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenylyl Cyclases; Animals; Bradykinin; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Epidermal Growth Factor; Epidermis; Epinephrine; Histamine; Isoquinolines; Keratinocytes; Piperazines; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1995 |
Epidermal growth factor inhibits carbachol-stimulated canine parietal cell function via protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminopyrine; Animals; Calcium; Carbachol; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dogs; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Gastric Acid; Inositol 1,4,5-Trisphosphate; Isoquinolines; Parasympathomimetics; Parietal Cells, Gastric; Piperazines; Protein Kinase C; Receptors, Muscarinic; Staurosporine; Sulfonamides | 1996 |
Suppression of growth-associated phosphorylation of proteins of fibroblasts by collagen fibrils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blood; Cell Division; Collagen; DNA; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblasts; Genistein; Humans; Hydrogen-Ion Concentration; Image Processing, Computer-Assisted; Isoflavones; Molecular Weight; Peptide Mapping; Phosphoproteins; Phosphorylation; Plastics; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Skin | 1996 |
Cytoplasmic desmosome formation by H-7 and EGF treatment in cultured fetal rat keratinocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Cytoplasm; Desmosomes; Embryonic and Fetal Development; Enzyme Inhibitors; Epidermal Growth Factor; Immunohistochemistry; Keratinocytes; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Skin | 1996 |
90-kDa S6 kinase is insufficient or not involved in the activation of glycogen synthase induced by insulin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cattle; Dose-Response Relationship, Drug; Epidermal Growth Factor; Glycogen Synthase; Insulin; Protein Serine-Threonine Kinases; Rabbits; Ribosomal Protein S6 Kinases | 1996 |
Overproduction of urokinase-type plasminogen activator is regulated by phospholipase D- and protein kinase C-dependent pathways in murine mammary adenocarcinoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Butanol; Adenocarcinoma; Animals; Butanols; Epidermal Growth Factor; Female; Mammary Neoplasms, Experimental; Mice; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Signal Transduction; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Up-Regulation; Urokinase-Type Plasminogen Activator | 1997 |
ATP- and EGF-stimulated phosphatidulinositol synthesis by two different pathways, phospholipase D and diacylglycerol kinase, in A-431 epidermoid carcinoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Bradykinin; Calcimycin; Calcium; Carcinoma, Squamous Cell; Chelating Agents; Choline; Diacylglycerol Kinase; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Ionophores; Neoplasm Proteins; Pertussis Toxin; Phosphatidic Acids; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Pyrimidinones; Receptors, Purinergic P2; Signal Transduction; Staurosporine; Sulfonamides; Thiazoles; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Regulation of heparin-binding EGF-like growth factor expression by phorbol ester in a human hepatoma-derived cell line.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoma, Hepatocellular; Cycloheximide; Epidermal Growth Factor; Gene Expression Regulation; Heparin; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Naphthalenes; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Function and expression of CD44 during spreading, migration, and invasion of murine carcinoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antibodies, Monoclonal; Carcinogens; Cell Adhesion; Cell Division; Cell Line; Cell Movement; Enzyme Inhibitors; Epidermal Growth Factor; Hyaluronan Receptors; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1998 |
Phosphatidic acid effects on cytosolic calcium and proliferation in osteoblastic cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Division; Cells, Cultured; Cytoplasm; Epidermal Growth Factor; Osteoblasts; Phosphatidic Acids; Phospholipase D; Propranolol; Protein Kinase C; Rats; Rats, Sprague-Dawley; Skull; Sphingosine; Thapsigargin; Verapamil | 1998 |
H-7 stimulates desmosome formation and inhibits growth in KB oral carcinoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Cell Adhesion; Cell Division; Desmosomes; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Immunohistochemistry; In Situ Nick-End Labeling; KB Cells | 1998 |
Epidermal growth factor-induced heterologous desensitization of the luteinizing hormone/choriogonadotropin receptor in a cell-free membrane preparation is associated with the tyrosine phosphorylation of the epidermal growth factor receptor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell-Free System; Chorionic Gonadotropin; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Membrane Proteins; Ovary; Pertussis Toxin; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Receptors, LH; Time Factors; Tyrosine; Virulence Factors, Bordetella | 1999 |
Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; DNA; DNA-Binding Proteins; Epidermal Growth Factor; Humans; Interleukin-6; Isoenzymes; Mitogen-Activated Protein Kinase 1; Phosphorylation; Protein Kinase C; Serine; STAT3 Transcription Factor; Trans-Activators; Transcriptional Activation | 1999 |
Activation of epidermal growth factor receptor promotes late terminal differentiation of cell-matrix interaction-disrupted keratinocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Differentiation; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Matrix; Filaggrin Proteins; Flavonoids; Humans; Intermediate Filament Proteins; Keratinocytes; Keratins; Mice; Protein Kinase C; Protein Precursors; Transglutaminases | 1999 |
Peroxynitrite modulates the activation of p38 and extracellular regulated kinases in PC12 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Nitrates; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Quinazolines; Rats; src-Family Kinases; Tyrphostins | 2000 |
Requirement of cortical actin organization for bombesin, endothelin, and EGF receptor internalization.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Actins; Animals; Bombesin; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gastrin-Releasing Peptide; GTP-Binding Proteins; Iodine Radioisotopes; Kinetics; Mice; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Receptors, Bombesin; Receptors, Endothelin; Signal Transduction; Thiazoles; Thiazolidines | 2000 |
Study on the mechanism of epidermal growth factor-induced proliferation of hepatoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoma, Hepatocellular; Cell Division; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; Liver Neoplasms; Sodium-Hydrogen Exchangers; Sulfonamides; Tumor Cells, Cultured | 2003 |
[Mechanism of signal transduction of differentiation of mesenchymal stem cells into cytokeratin-expressing epidermoid cells].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Epidermal Cells; Epidermal Growth Factor; Epidermis; Female; Flavonoids; Flow Cytometry; Hyaluronan Receptors; Imidazoles; Immunohistochemistry; Integrin beta1; Keratin-19; Keratins; Male; Mechanotransduction, Cellular; Mesenchymal Stem Cells; Pyridines; Rats; Rats, Wistar; Time Factors | 2006 |
Effect of RhoA signaling transduction on expression of Ezrin in breast cancer cell lines.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cytoskeletal Proteins; Epidermal Growth Factor; Humans; Phosphorylation; rhoA GTP-Binding Protein; Signal Transduction; Time Factors | 2009 |