1-(5-isoquinolinesulfonyl)-2-methylpiperazine and epidermal growth factor

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with epidermal growth factor in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.88)18.7374
1990's34 (82.93)18.2507
2000's5 (12.20)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kobuchi, H; Li, MJ; Matsuno, T; Utsumi, K; Yasuda, T1
Kobayashi, T1
Ikeda, K; Kikuchi, T; Matsumoto, T; Morimoto, K; Nakano, T; Ogata, E; Okazaki, R; Sakamoto, A; Urakawa, K1
Joyce, NC; Meklir, B1
Hamm, LL; Herndon, J; Vehaskari, VM1
Cao, XM; Guy, GR; Sukhatme, VP; Tan, YH1
Albright, CD; Fontana, JA; Grimley, PM; Jones, RT; Keenan, KP; Resau, JH1
Moore, JJ; Moore, RM; Vander Kooy, D1
Deuel, TF; Shawver, LK1
Emoto, T; Hattori, Y; Hiraiwa, M; Kasai, K; Kuroda, H; Shimoda, S; Yamazaki, A1
Teitelbaum, I1
Fujiwara, K; Hirata, K1
Aizu, E; Kato, R; Nakadate, T; Nishikawa, K; Yamamoto, S1
Gross, JL; Morrison, RS; Moskal, JR1
Eling, TE; Hamasaki, Y1
Goishi, K; Higashiyama, S; Ishikawa, M; Klagsbrun, M; Mekada, E; Nakano, N; Taniguchi, N; Umata, T1
Boccone, L; Maiese, K1
Maiese, K1
Fusamoto, H; Hayashi, N; Horimoto, M; Ito, T; Kamada, T; Kaneko, A; Kasahara, A; Sasaki, Y; Tanaka, Y1
Ando, Y; Jensen, PJ; Lazarus, GS1
Boniece, IR; Wagner, JA1
Harada, H; Motomura, A; Suketa, Y; Suzuki, S; Tai, H1
Hashimoto, Y; Iizuka, H; Ishida-Yamamoto, A; Takahashi, H1
DelValle, J; Osburn, J; Wang, L; Wilson, EJ1
Koseki, N; Sato, H; Yoshizato, K1
Amar, L; Forest, N; Martin, N; Oboeuf, M; Shabana, AH1
Hidaka, H; Niki, I; Yasui, K1
Aguirre Ghiso, JA; Alonso, DF; Bal de Kier Joffé, E; Farías, EF1
Atsumi, T; Hosoi, K; Kurihara, K; Shioda, Y; Sugita, K; Ueha, T1
Higashiyama, S; Ito, N; Kawata, S; Kiso, S; Matsuzawa, Y; Nakagawa, T; Tamura, S; Taniguchi, N; Tsushima, H1
Aguirre Ghiso, JA; Bal de Kier Joffé, E; Ladeda, V1
Carpio, LC; Dziak, R1
Forest, N; Goldberg, M; Lecolle, S; Shabana, AH1
Hunzicker-Dunn, M; Lamm, ML; Rajagopalan-Gupta, RM1
Cao, X; Jain, N; Kee, WH; Li, W; Zhang, T1
Takigawa, M; Wakita, H1
Jope, RS; Song, L; Zhang, L1
Lunn, JA; Rozengurt, E; Walsh, JH; Wong, H1
Cui, WR; Li, A; Lin, JS; Wang, JL; Wu, BW; Wu, Y; Yuan, SY1
Bai, XD; Fu, XB; Sun, TZ; Zhang, Q1
Geng, CZ; Liu, YP; Ma, L; Wang, JL; Xing, LX; Zhang, XH1

Other Studies

41 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and epidermal growth factor

ArticleYear
Inhibition of neutrophil priming and tyrosyl phosphorylation by cepharanthine, a nonsteroidal antiinflammatory drug.
    Cell structure and function, 1992, Volume: 17, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Annexin A1; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Epidermal Growth Factor; Granulocyte Colony-Stimulating Factor; Humans; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Phosphorylation; Piperazines; Protein-Tyrosine Kinases; Respiratory Burst; Tumor Necrosis Factor-alpha

1992
[Sulfolipids and glycolipid sulfotransferases in a human renal cell carcinoma cell line].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1992, Volume: 67, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Carcinoma, Renal Cell; Epidermal Growth Factor; Humans; Isoquinolines; Kidney Neoplasms; Lipid Metabolism; Lipids; Piperazines; Protein Kinase C; Staurosporine; Sulfotransferases; Sulfurtransferases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Transcriptional activation of c-fos and c-jun protooncogenes by serum growth factors in osteoblast-like MC3T3-E1 cells.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1992, Volume: 7, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Cell Differentiation; Cycloheximide; Dactinomycin; Epidermal Growth Factor; Fibroblast Growth Factor 2; Gene Expression Regulation; Growth Substances; Insulin-Like Growth Factor I; Isoquinolines; Mice; Osteoblasts; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; RNA, Messenger; Staurosporine; Transforming Growth Factor beta

1992
Protein kinase C activation during corneal endothelial wound repair.
    Investigative ophthalmology & visual science, 1992, Volume: 33, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Cell Movement; Cells, Cultured; Endothelium, Corneal; Enzyme Activation; Epidermal Growth Factor; Fluorescent Antibody Technique; Fluorescent Dyes; Isoquinolines; Male; Phalloidine; Piperazines; Protein Kinase C; Rabbits; Rhodamines; Sphingosine; Tetradecanoylphorbol Acetate; Wound Healing

1992
Mechanism of sodium transport inhibition by epidermal growth factor in cortical collecting ducts.
    The American journal of physiology, 1991, Volume: 261, Issue:5 Pt 2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Biological Transport, Active; Calcium; Carrier Proteins; Desoxycorticosterone; Epidermal Growth Factor; Indomethacin; Isoquinolines; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Pertussis Toxin; Piperazines; Protein Kinase C; Rabbits; Reference Values; Sodium; Sodium-Hydrogen Exchangers; Virulence Factors, Bordetella

1991
Regulation of the Egr-1 gene by tumor necrosis factor and interferons in primary human fibroblasts.
    The Journal of biological chemistry, 1992, Jan-15, Volume: 267, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Blotting, Northern; Blotting, Western; DNA; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; HeLa Cells; Humans; Interferon-gamma; Isoquinolines; Kinetics; Mice; Phosphorylation; Piperazines; RNA, Messenger; Staurosporine; Sulfonamides; Thymidine; Tumor Necrosis Factor-alpha

1992
Cell-to-cell communication: a differential response to TGF-beta in normal and transformed (BEAS-2B) human bronchial epithelial cells.
    Carcinogenesis, 1991, Volume: 12, Issue:11

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bronchi; Bronchial Neoplasms; Calmodulin; Cell Communication; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Down-Regulation; Epidermal Growth Factor; Epithelium; Humans; Isoquinolines; Piperazines; Protein Kinase Inhibitors; Sulfonamides; Time Factors; Transforming Growth Factor beta

1991
Protein kinase-C activation is required for oxytocin-induced prostaglandin production in human amnion cells.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Activation; Epidermal Growth Factor; Female; Humans; Isoquinolines; Oxytocin; Phorbol Esters; Piperazines; Pregnancy; Protein Kinase C; RNA, Messenger; Staurosporine; Time Factors; Type C Phospholipases

1991
Nuclear pp64 is phosphorylated in both serine/threonine and tyrosine through complex pathways regulated by 12-O-tetradecanoylphorbol-13-acetate and platelet-derived growth factor.
    Biochemical and biophysical research communications, 1990, Mar-30, Volume: 167, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Dimethyl Sulfoxide; Epidermal Growth Factor; Isoquinolines; Kinetics; Nuclear Proteins; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

1990
Inhibition by protein kinase-C inhibitor and cycloheximide of phorbol ester- and epidermal growth factor-induced arachidonic acid metabolism in cultured porcine thyroid cells.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:7

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cycloheximide; Dinoprostone; Epidermal Growth Factor; Isoquinolines; Kinetics; Male; Mice; Piperazines; Protein Kinase C; Sulfonamides; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland

1990
Cyclic adenosine monophosphate and diacylglycerol. Mutually inhibitory second messengers in cultured rat inner medullary collecting duct cells.
    The Journal of clinical investigation, 1990, Volume: 86, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Cyclic AMP; Diglycerides; Dinoprostone; Epidermal Growth Factor; Glycerides; In Vitro Techniques; Inositol Phosphates; Isoquinolines; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Piperazines; Protein Kinase Inhibitors; Rats; Signal Transduction; Type C Phospholipases

1990
Possible contribution of protein kinase C activation to priming for DNA synthesis induced by epidermal growth factor with insulin and its inhibition by plasma membrane in primary cultured rat hepatocytes.
    Biochemical and biophysical research communications, 1990, Sep-28, Volume: 171, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channel Blockers; Cell Membrane; Cells, Cultured; DNA; DNA Replication; Enzyme Activation; Epidermal Growth Factor; Insulin; Isoquinolines; Liver; Male; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Vasopressins

1990
H-7, a protein kinase C inhibitor, inhibits phorbol ester-caused ornithine decarboxylase induction but fails to inhibit phorbol ester-caused suppression of epidermal growth factor binding in primary cultured mouse epidermal cells.
    Molecular pharmacology, 1989, Volume: 36, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Enzyme Induction; Epidermal Growth Factor; Epidermis; Isoquinolines; Mice; Ornithine Decarboxylase; Phosphorylation; Piperazines; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate

1989
Inhibition of protein kinase C activity promotes the neurotrophic action of epidermal and basic fibroblast growth factors.
    Brain research, 1988, Nov-08, Volume: 473, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Dendrites; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblast Growth Factors; Isoquinolines; Phorbol Esters; Piperazines; Protein Kinase C; Rats

1988
EGF and TPA stimulate de novo synthesis of PGHS-1 and PGHS-2 through different signal transduction pathways.
    Prostaglandins, leukotrienes, and essential fatty acids, 1995, Volume: 53, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Line, Transformed; Cinnamates; Dinoprostone; Enzyme Inhibitors; Epidermal Growth Factor; Epithelium; Isoquinolines; Piperazines; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Trachea

1995
Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity.
    Molecular biology of the cell, 1995, Volume: 6, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acids; Animals; Anti-Bacterial Agents; Cell Membrane; Chlorocebus aethiops; Diphtheria Toxin; DNA; Endosomes; Enzyme Inhibitors; Epidermal Growth Factor; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Isoquinolines; Kinetics; Macrolides; Molecular Weight; Piperazines; Protein Kinase C; Protein Precursors; Protein Processing, Post-Translational; Staurosporine; Tetradecanoylphorbol Acetate; Vero Cells

1995
Neuroprotection by peptide growth factors against anoxia and nitric oxide toxicity requires modulation of protein kinase C.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1995, Volume: 15, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Down-Regulation; Epidermal Growth Factor; Fibroblast Growth Factor 2; Hypoxia, Brain; Isoquinolines; Neurons; Neuroprotective Agents; Nitric Oxide; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley

1995
Protein kinase C modulates the protective ability of peptide growth factors during anoxia.
    Journal of the autonomic nervous system, 1994, Volume: 49 Suppl

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Death; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; Fibroblast Growth Factor 2; Growth Substances; Hippocampus; Hypoxia, Brain; Isoquinolines; Neurons; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley

1994
Characterization of signaling pathways to Na+/H+ exchanger activation with epidermal growth factor in hepatocytes.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:4 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium; Calcium-Transporting ATPases; Calmodulin; Cells, Cultured; Epidermal Growth Factor; Genistein; Hydrogen-Ion Concentration; Isoflavones; Isoquinolines; Liver; Male; Phenylephrine; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin

1994
Activation of protein kinase C inhibits human keratinocyte migration.
    Journal of cellular physiology, 1993, Volume: 156, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Catechols; Cell Movement; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Growth Substances; Humans; Isoquinolines; Keratinocytes; Nitriles; Phorbol Esters; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Tyrphostins

1993
Growth factors protect PC12 cells against ischemia by a mechanism that is independent of PKA, PKC, and protein synthesis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Anisomycin; Cell Hypoxia; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Fibroblast Growth Factor 2; Ischemia; Isoquinolines; Kinetics; Models, Biological; Neoplasm Proteins; Nerve Growth Factors; PC12 Cells; Phosphorylation; Piperazines; Protein Kinase C; Staurosporine; Time Factors

1993
Extracellular ATP-induced regulation of epidermal growth factor signaling in cultured renal LLC-PK1 cells.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Animals; Cell Line; Cell Membrane; Cytosol; Epidermal Growth Factor; ErbB Receptors; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kidney; Kinetics; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate

1993
Activators of protein kinase C but not of phospholipase C modulate adenylate cyclase-responses of normal pig epidermis.
    Epithelial cell biology, 1995, Volume: 4, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenylyl Cyclases; Animals; Bradykinin; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Epidermal Growth Factor; Epidermis; Epinephrine; Histamine; Isoquinolines; Keratinocytes; Piperazines; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases

1995
Epidermal growth factor inhibits carbachol-stimulated canine parietal cell function via protein kinase C.
    Gastroenterology, 1996, Volume: 110, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminopyrine; Animals; Calcium; Carbachol; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dogs; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Gastric Acid; Inositol 1,4,5-Trisphosphate; Isoquinolines; Parasympathomimetics; Parietal Cells, Gastric; Piperazines; Protein Kinase C; Receptors, Muscarinic; Staurosporine; Sulfonamides

1996
Suppression of growth-associated phosphorylation of proteins of fibroblasts by collagen fibrils.
    Cell adhesion and communication, 1996, Volume: 3, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blood; Cell Division; Collagen; DNA; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblasts; Genistein; Humans; Hydrogen-Ion Concentration; Image Processing, Computer-Assisted; Isoflavones; Molecular Weight; Peptide Mapping; Phosphoproteins; Phosphorylation; Plastics; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Skin

1996
Cytoplasmic desmosome formation by H-7 and EGF treatment in cultured fetal rat keratinocytes.
    Tissue & cell, 1996, Volume: 28, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Cytoplasm; Desmosomes; Embryonic and Fetal Development; Enzyme Inhibitors; Epidermal Growth Factor; Immunohistochemistry; Keratinocytes; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Skin

1996
90-kDa S6 kinase is insufficient or not involved in the activation of glycogen synthase induced by insulin.
    European journal of pharmacology, 1996, Dec-05, Volume: 316, Issue:2-3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cattle; Dose-Response Relationship, Drug; Epidermal Growth Factor; Glycogen Synthase; Insulin; Protein Serine-Threonine Kinases; Rabbits; Ribosomal Protein S6 Kinases

1996
Overproduction of urokinase-type plasminogen activator is regulated by phospholipase D- and protein kinase C-dependent pathways in murine mammary adenocarcinoma cells.
    Biochimica et biophysica acta, 1997, Apr-24, Volume: 1356, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Butanol; Adenocarcinoma; Animals; Butanols; Epidermal Growth Factor; Female; Mammary Neoplasms, Experimental; Mice; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Signal Transduction; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Up-Regulation; Urokinase-Type Plasminogen Activator

1997
ATP- and EGF-stimulated phosphatidulinositol synthesis by two different pathways, phospholipase D and diacylglycerol kinase, in A-431 epidermoid carcinoma cells.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1996, Volume: 74, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Bradykinin; Calcimycin; Calcium; Carcinoma, Squamous Cell; Chelating Agents; Choline; Diacylglycerol Kinase; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Ionophores; Neoplasm Proteins; Pertussis Toxin; Phosphatidic Acids; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Pyrimidinones; Receptors, Purinergic P2; Signal Transduction; Staurosporine; Sulfonamides; Thiazoles; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella

1996
Regulation of heparin-binding EGF-like growth factor expression by phorbol ester in a human hepatoma-derived cell line.
    Biochimica et biophysica acta, 1996, Jan-10, Volume: 1310, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoma, Hepatocellular; Cycloheximide; Epidermal Growth Factor; Gene Expression Regulation; Heparin; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Naphthalenes; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1996
Function and expression of CD44 during spreading, migration, and invasion of murine carcinoma cells.
    Experimental cell research, 1998, Aug-01, Volume: 242, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antibodies, Monoclonal; Carcinogens; Cell Adhesion; Cell Division; Cell Line; Cell Movement; Enzyme Inhibitors; Epidermal Growth Factor; Hyaluronan Receptors; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1998
Phosphatidic acid effects on cytosolic calcium and proliferation in osteoblastic cells.
    Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 59, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Division; Cells, Cultured; Cytoplasm; Epidermal Growth Factor; Osteoblasts; Phosphatidic Acids; Phospholipase D; Propranolol; Protein Kinase C; Rats; Rats, Sprague-Dawley; Skull; Sphingosine; Thapsigargin; Verapamil

1998
H-7 stimulates desmosome formation and inhibits growth in KB oral carcinoma cells.
    Microscopy research and technique, 1998, Nov-01, Volume: 43, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Cell Adhesion; Cell Division; Desmosomes; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Immunohistochemistry; In Situ Nick-End Labeling; KB Cells

1998
Epidermal growth factor-induced heterologous desensitization of the luteinizing hormone/choriogonadotropin receptor in a cell-free membrane preparation is associated with the tyrosine phosphorylation of the epidermal growth factor receptor.
    Endocrinology, 1999, Volume: 140, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell-Free System; Chorionic Gonadotropin; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Membrane Proteins; Ovary; Pertussis Toxin; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Receptors, LH; Time Factors; Tyrosine; Virulence Factors, Bordetella

1999
Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner.
    The Journal of biological chemistry, 1999, Aug-20, Volume: 274, Issue:34

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; DNA; DNA-Binding Proteins; Epidermal Growth Factor; Humans; Interleukin-6; Isoenzymes; Mitogen-Activated Protein Kinase 1; Phosphorylation; Protein Kinase C; Serine; STAT3 Transcription Factor; Trans-Activators; Transcriptional Activation

1999
Activation of epidermal growth factor receptor promotes late terminal differentiation of cell-matrix interaction-disrupted keratinocytes.
    The Journal of biological chemistry, 1999, Dec-24, Volume: 274, Issue:52

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Differentiation; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Matrix; Filaggrin Proteins; Flavonoids; Humans; Intermediate Filament Proteins; Keratinocytes; Keratins; Mice; Protein Kinase C; Protein Precursors; Transglutaminases

1999
Peroxynitrite modulates the activation of p38 and extracellular regulated kinases in PC12 cells.
    Archives of biochemistry and biophysics, 2000, Apr-15, Volume: 376, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Nitrates; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Quinazolines; Rats; src-Family Kinases; Tyrphostins

2000
Requirement of cortical actin organization for bombesin, endothelin, and EGF receptor internalization.
    American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Actins; Animals; Bombesin; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gastrin-Releasing Peptide; GTP-Binding Proteins; Iodine Radioisotopes; Kinetics; Mice; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Receptors, Bombesin; Receptors, Endothelin; Signal Transduction; Thiazoles; Thiazolidines

2000
Study on the mechanism of epidermal growth factor-induced proliferation of hepatoma cells.
    World journal of gastroenterology, 2003, Volume: 9, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoma, Hepatocellular; Cell Division; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; Liver Neoplasms; Sodium-Hydrogen Exchangers; Sulfonamides; Tumor Cells, Cultured

2003
[Mechanism of signal transduction of differentiation of mesenchymal stem cells into cytokeratin-expressing epidermoid cells].
    Zhonghua yi xue za zhi, 2006, May-16, Volume: 86, Issue:18

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Epidermal Cells; Epidermal Growth Factor; Epidermis; Female; Flavonoids; Flow Cytometry; Hyaluronan Receptors; Imidazoles; Immunohistochemistry; Integrin beta1; Keratin-19; Keratins; Male; Mechanotransduction, Cellular; Mesenchymal Stem Cells; Pyridines; Rats; Rats, Wistar; Time Factors

2006
Effect of RhoA signaling transduction on expression of Ezrin in breast cancer cell lines.
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cytoskeletal Proteins; Epidermal Growth Factor; Humans; Phosphorylation; rhoA GTP-Binding Protein; Signal Transduction; Time Factors

2009