1-(5-isoquinolinesulfonyl)-2-methylpiperazine and dactinomycin

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Differentiation; Cell Division; Cycloheximide; Dactinomycin; Ethers, Cyclic; Gene Expression Regulation, Leukemic; Genes, jun; Humans; Isoquinolines; Lymphoma, Large B-Cell, Diffuse; Male; Monocytes; Neoplasm Proteins; Neoplastic Stem Cells; Okadaic Acid; Piperazines; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Base Sequence; Cycloheximide; Dactinomycin; Humans; Isoquinolines; Molecular Sequence Data; Neurites; Neuroblastoma; Neurofilament Proteins; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rats; RNA, Messenger; RNA, Neoplasm; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Cell Differentiation; Cycloheximide; Dactinomycin; Epidermal Growth Factor; Fibroblast Growth Factor 2; Gene Expression Regulation; Growth Substances; Insulin-Like Growth Factor I; Isoquinolines; Mice; Osteoblasts; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; RNA, Messenger; Staurosporine; Transforming Growth Factor beta

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Northern; Blotting, Western; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Induction; Epinephrine; Gene Expression; Isoquinolines; Mice; Osteoblasts; Piperazines; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Astrocytoma; Dactinomycin; Glial Fibrillary Acidic Protein; Humans; Isoquinolines; Piperazines; Protein Kinase C; RNA; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aphidicolin; Cell Line; Cell Nucleus; Cycloheximide; Cytarabine; Dactinomycin; Diterpenes; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; RNA, Neoplasm; Sulfonamides; Transcription Factors; Transcription, Genetic

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Bacterial Toxins; Calcimycin; Camptothecin; Cell Survival; Cells, Cultured; Cycloheximide; Dactinomycin; Endotoxins; Enterotoxins; Enzyme Activation; Isoquinolines; Macrophages; Male; Piperazines; Protein Biosynthesis; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Thromboxane B2

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbohydrates; Cells, Cultured; Cyclic AMP; Cycloheximide; Dactinomycin; Gene Expression Regulation, Enzymologic; Glucokinase; Hormones; Isoenzymes; Isoquinolines; Liver; Male; Piperazines; Protein Kinase C; Pyruvate Kinase; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate; Thionucleotides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Activation; Epidermal Growth Factor; Female; Humans; Isoquinolines; Oxytocin; Phorbol Esters; Piperazines; Pregnancy; Protein Kinase C; RNA, Messenger; Staurosporine; Time Factors; Type C Phospholipases

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antigen-Antibody Reactions; Antigens, Differentiation, T-Lymphocyte; Calcium; CD3 Complex; Cell Survival; Cycloheximide; Dactinomycin; DNA Damage; Dose-Response Relationship, Immunologic; Hybridomas; In Vitro Techniques; Interleukin-2; Isoquinolines; Lymphocyte Activation; Mice; Piperazines; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Time Factors

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Nucleus; Cells, Cultured; Concanavalin A; Cycloheximide; Dactinomycin; Endonucleases; Interleukin-1; Isoquinolines; Kinetics; Male; Phorbol 12,13-Dibutyrate; Piperazines; Protease Inhibitors; Protein Biosynthesis; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; RNA, Messenger; Thymus Gland

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Endothelium, Vascular; Gene Expression; In Vitro Techniques; Inflammation; Interleukin-1; Isoquinolines; Lymphocytes; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Signal Transduction; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Chickens; Cyclic AMP; Cycloheximide; Dactinomycin; Female; Granulosa Cells; In Vitro Techniques; Isoquinolines; L-Lactate Dehydrogenase; Luteinizing Hormone; Piperazines; Plasminogen Activators; Progesterone; Protein Kinase C; Sheep; Tetradecanoylphorbol Acetate

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Cell Survival; Cycloheximide; Dactinomycin; DNA Damage; Isoquinolines; Lectins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Peanut Agglutinin; Phenotype; Piperazines; T-Lymphocytes; Tetradecanoylphorbol Acetate

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cells, Cultured; Cycloheximide; Dactinomycin; Diglycerides; Enzyme Activation; Glycerides; Humans; Isoquinolines; Melanins; Piperazines; Protein Kinase C; Skin Pigmentation; Sphingosine

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-MSH; Animals; Axons; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; Fluorescent Antibody Technique; Isoquinolines; Melanocyte-Stimulating Hormones; Melanoma; Mice; Microscopy, Electron; Piperazines; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcitriol; Cell Division; Cells, Cultured; Cyclic AMP; Cycloheximide; Dactinomycin; DNA; Drug Synergism; Growth Plate; Isoquinolines; Parathyroid Hormone; Peptide Fragments; Piperazines; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Calcitriol; Tetradecanoylphorbol Acetate; Thymidine; Tritium

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Biomarkers; Cells, Cultured; Cycloheximide; Dactinomycin; Fluorescence; Isoquinolines; Piperazines; Protein Kinase C; Rana catesbeiana; RNA; Tail; Thyroxine; Time Factors; Ubiquitins

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Macroglobulins; Animals; Cell Line; Dactinomycin; Drug Synergism; Ethers, Cyclic; Extracellular Matrix; Fibroblast Growth Factor 2; Gene Expression; Humans; Isoquinolines; Macrophages; Methylamines; Mice; Microcystins; Okadaic Acid; Peptides, Cyclic; Piperazines; Plasminogen Activator Inhibitor 1; Protein Kinase C; RNA, Messenger; Transforming Growth Factor beta; Urokinase-Type Plasminogen Activator

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Base Sequence; Dactinomycin; Gene Expression Regulation, Leukemic; Humans; Interleukin-3; Isoquinolines; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; Naphthalenes; Neoplasm Proteins; Piperazines; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Interleukin-3; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Northern; Carrier Proteins; Cell Differentiation; Cell Division; Cycloheximide; Dactinomycin; Enzyme Activation; gamma-Glutamyltransferase; Gene Expression; Glucose; Isoquinolines; Kidney; Kinetics; LLC-PK1 Cells; Membrane Glycoproteins; Membrane Proteins; Monosaccharide Transport Proteins; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; RNA, Messenger; Sodium; Sodium-Glucose Transporter 1; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Gene Expression Regulation; Glucose; Hydrogen-Ion Concentration; Isoquinolines; Muscle, Smooth, Vascular; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Hydrogen Exchangers

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Arachidonic Acid; Aspirin; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Female; Humans; Isoquinolines; Piperazines; Pregnancy; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Analysis of Variance; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; Emetine; Female; Humans; Interferon alpha-2; Interferon-alpha; Isoquinolines; Ovarian Neoplasms; Piperazines; Protein Biosynthesis; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cell Division; Cells, Cultured; Chymotrypsin; Dactinomycin; Fibronectins; Humans; Isoquinolines; Kinetics; L Cells; Lipopolysaccharides; Mice; Monocytes; Peptide Fragments; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides; Time Factors; Tumor Necrosis Factor-alpha

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Biological Transport; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Isoquinolines; Kidney; Opossums; Phosphates; Piperazines; Protein Serine-Threonine Kinases; Signal Transduction; Time Factors; Transforming Growth Factor beta

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow Cells; Cell Line; Cell Nucleus; Dactinomycin; DNA Probes; Enzyme Inhibitors; Gene Expression Regulation; Genistein; Interleukin-11; Isoflavones; Isoquinolines; Kinetics; Luciferases; Naphthalenes; Open Reading Frames; Piperazines; Primates; Protein Kinase C; Recombinant Fusion Proteins; RNA Processing, Post-Transcriptional; RNA, Messenger; Stromal Cells; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transfection

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Base Sequence; Bone Marrow; Bone Marrow Cells; Cattle; Cells, Cultured; Connective Tissue; Culture Media; Cycloheximide; Dactinomycin; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Inhibitors; Fetal Blood; Gene Expression Regulation; Genes, Immediate-Early; Humans; Immediate-Early Proteins; Interleukin-1; Isoquinolines; Molecular Sequence Data; Osteoblasts; Piperazines; Protein Kinase C; Protein Synthesis Inhibitors; Transcription Factors; Tumor Necrosis Factor-alpha

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carcinogens; Cells, Cultured; Cyclic AMP; Cycloheximide; Cyclooxygenase Inhibitors; Dactinomycin; Dinoprost; Enzyme Inhibitors; Female; Gonadotropins; Indomethacin; Ovulation; Phorbol Esters; Protein Synthesis Inhibitors; Radioimmunoassay; Ranidae

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Butyrates; Butyric Acid; Calcium; Chelating Agents; Colonic Neoplasms; Cycloheximide; Dactinomycin; Deoxycholic Acid; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Genistein; Humans; Isoflavones; Propionates; Protein Synthesis Inhibitors; Time Factors; Tumor Cells, Cultured

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blotting, Northern; Cell Line; Cycloheximide; Dactinomycin; Endothelium; Enzyme Inhibitors; Gene Expression Regulation; Imidazoles; Losartan; Membrane Glycoproteins; Myocardium; Protein Kinase C; Pyridines; Rats; Tetrazoles; Thrombospondins

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Isoenzymes; Isoquinolines; Lactams, Macrocyclic; Male; Mice; Mice, Inbred BALB C; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Quinones; Rifabutin; RNA; Sulfonamides; T-Lymphocytes; Thymus Gland

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Calcium; Cells, Cultured; Dactinomycin; DNA-Binding Proteins; Gene Expression Regulation; Humans; Interferon Regulatory Factor-1; Interferon-gamma; Keratinocytes; Phosphoproteins; RNA, Messenger; Tetradecanoylphorbol Acetate

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Antihypertensive Agents; Blotting, Northern; Cattle; Culture Media, Conditioned; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; Immunoblotting; Losartan; Lymphokines; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Rats; RNA, Messenger; Transcription Factors; Transcriptional Activation; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasoconstrictor Agents

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Neoplasm; Blast Crisis; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Half-Life; Humans; Ki-1 Antigen; Leukemia, Erythroblastic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Aquaporin 4; Aquaporins; Astrocytes; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies; Carrier Proteins; Cell Cycle Proteins; Dactinomycin; Dichlororibofuranosylbenzimidazole; DNA Damage; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression Regulation; Humans; Mutation; Nuclear Proteins; Oligonucleotides, Antisense; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Retinoblastoma-Binding Protein 1; RNA, Messenger; Transcription Factor DP1; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Calcimycin; Calcium; Calmodulin; Caspases; Cell Line; Chelating Agents; Cycloheximide; Dactinomycin; DNA Fragmentation; Drosophila melanogaster; Egtazic Acid; Enzyme Inhibitors; Ionophores; Neurons; Protein Synthesis Inhibitors; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Caspase 3; Caspases; Dactinomycin; Daunorubicin; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Hydrogen Peroxide; Hydroxyl Radical; Nucleic Acid Synthesis Inhibitors

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adjuvants, Immunologic; Amino Acid Transport Systems; Amino Acids; Aminoisobutyric Acids; Blotting, Northern; Carrier Proteins; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Poly A; Protein Binding; Protein Synthesis Inhibitors; RNA, Messenger; Sodium; Substrate Specificity; Time Factors; Tumor Cells, Cultured

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Embryo Implantation; Endometrium; Enzyme Inhibitors; Female; Humans; Middle Aged; Protein Kinase C; Protein Synthesis Inhibitors; Stromal Cells; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antineoplastic Agents; Apoptosis; Butadienes; Caspase 3; Caspases; Cell Division; Cell Line, Tumor; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Neoplasm; Enzyme Inhibitors; Melanoma; Mice; Nitriles; Phosphorylation; Protein Kinase C; Tumor Necrosis Factor-alpha

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Breast; Breast Neoplasms; Concanavalin A; Cycloheximide; Dactinomycin; Enzyme Activation; Enzyme Activators; Female; Fibroadenoma; Gelatin; Humans; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Organ Culture Techniques; Protease Inhibitors; Protein Biosynthesis; Protein Kinase C; Protein Synthesis Inhibitors; Transcription, Genetic

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzazepines; Cell Line; Cisplatin; Cricetinae; Cricetulus; Cross-Linking Reagents; Dactinomycin; Enzyme Inhibitors; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Indoles; Photobleaching; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Subunits; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; RNA Polymerase II; Transcription, Genetic; Ultraviolet Rays

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Benzenesulfonates; Calcium Channel Blockers; Calcium Signaling; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Dactinomycin; Homeostasis; Humans; Interleukin-1beta; Luminescent Measurements; Periodontal Ligament; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; RNA, Small Interfering; Signal Transduction; Stress, Mechanical; Suramin; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation