1-(5-isoquinolinesulfonyl)-2-methylpiperazine and concanavalin a

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with concanavalin a in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's13 (76.47)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fredholm, BB; Jondal, M; Kontny, E; Kvanta, A; Okret, S1
Alberola-Ila, J; Lozano, F; Places, L; Vives, J1
Bell, SC; Capetola, RJ; Goodman, MG; Gupta, S; Rosenthale, ME; Weigle, WO1
Ishida, E; Ito, M; Sato, A; Shigeta, S; Tanabe, F1
Iwata, K; Sasaki, Y1
Hartzell, P; McConkey, DJ; Orrenius, S1
Kato, K; Morimura, S; Tashiro, F; Ueno, Y1
Sasaki, Y1
Bixby, JL1
Fan, SG; Lee, CM; Xu, H1
Chatila, TA; Geha, RS1
Cazaux, CA; Cremaschi, GA; Gorelik, G; Sterin-Borda, L1
Dobrovinskaya, OR; Eidus, LKh; Korystov, YN; Shaposhnikova, VV1
Ichikawa, T; Yano, T1
Blanchette, F; Cironi, L; Maghni, K; Pouliot, N; Rola-Pleszczynski, M; Sirois, P; Stankova, J1
Berke, G; Kaplan, MR; Trubniykov, E1
Hsieh, HY; Hsieh, YS; Huang, CY; Kuo, SJ; Liu, JY; Tsai, JH; Wu, TT; Yu, SY1

Other Studies

17 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and concanavalin a

ArticleYear
Mitogen stimulation of T-cells increases c-Fos and c-Jun protein levels, AP-1 binding and AP-1 transcriptional activity.
    Cellular signalling, 1992, Volume: 4, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Concanavalin A; Gene Expression Regulation; Humans; Isoquinolines; Lectins; Phorbol Esters; Phytohemagglutinins; Piperazines; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; T-Lymphocytes; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1992
Effect of protein kinase C activators on the phosphorylation and the surface expression of the CDw50 leukocyte antigen.
    European journal of biochemistry, 1992, Jan-15, Volume: 203, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Antigens, CD; Antigens, Differentiation; Cell Adhesion Molecules; Concanavalin A; Cross-Linking Reagents; Diterpenes; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Flow Cytometry; Fluorescent Antibody Technique; Humans; Isoquinolines; Kinetics; Lymphocytes; Phorbol 12,13-Dibutyrate; Phosphorylation; Phytohemagglutinins; Piperazines; Precipitin Tests; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate

1992
Protein kinase C independent restoration of specific immune responsiveness in common variable immunodeficiency.
    Clinical immunology and immunopathology, 1991, Volume: 59, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Alkaloids; Antibody Formation; Antigens, CD; Cell Division; Concanavalin A; Dose-Response Relationship, Drug; Female; Guanosine; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunologic Deficiency Syndromes; Immunophenotyping; In Vitro Techniques; Isoquinolines; Lymphocytes; Male; Middle Aged; Piperazines; Pokeweed Mitogens; Protein Kinase C; Protein Kinase Inhibitors; Signal Transduction; Sphingosine; Staurosporine

1991
Protein kinase C inhibitors enhance concanavalin A cap formation in polymorphonuclear leukocytes.
    International journal of immunopharmacology, 1990, Volume: 12, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Colchicine; Concanavalin A; Cytosol; Female; Fluorescein-5-isothiocyanate; Fluoresceins; In Vitro Techniques; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Neutrophils; Piperazines; Protein Kinase C; Thiocyanates

1990
Concanavalin A- and fetal-calf-serum-induced rounding and myosin light chain phosphorylation in cultured smooth muscle cells.
    Journal of cellular physiology, 1990, Volume: 144, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Blood; Calcimycin; Calcium; Cells, Cultured; Chickens; Concanavalin A; Culture Media; Cytochalasin B; Cytochalasins; Diltiazem; Egtazic Acid; Gizzard, Avian; Ionomycin; Isoquinolines; Kinetics; Muscle, Smooth; Muscle, Smooth, Vascular; Myosin Subfragments; Phosphorylation; Rabbits; Verapamil

1990
Rapid turnover of endogenous endonuclease activity in thymocytes: effects of inhibitors of macromolecular synthesis.
    Archives of biochemistry and biophysics, 1990, Volume: 278, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Nucleus; Cells, Cultured; Concanavalin A; Cycloheximide; Dactinomycin; Endonucleases; Interleukin-1; Isoquinolines; Kinetics; Male; Phorbol 12,13-Dibutyrate; Piperazines; Protease Inhibitors; Protein Biosynthesis; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; RNA, Messenger; Thymus Gland

1990
Modulation of c-myc gene expression by extracellular stimuli in rat hepatoma cells.
    The Japanese journal of experimental medicine, 1990, Volume: 60, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Northern; Concanavalin A; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Gene Expression; Insulin; Insulin Antagonists; Isoquinolines; Liver Neoplasms, Experimental; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Inhibition of myosin light chain phosphorylation in cultured smooth muscle cells by HA1077, a new type of vasodilator.
    Biochemical and biophysical research communications, 1990, Sep-28, Volume: 171, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Cells, Cultured; Concanavalin A; Isoquinolines; Kinetics; Muscle, Smooth, Vascular; Myosin Subfragments; Phosphorylation; Rabbits; Vasodilator Agents

1990
Protein kinase C is involved in laminin stimulation of neurite outgrowth.
    Neuron, 1989, Volume: 3, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Axons; Chick Embryo; Concanavalin A; Cyclic AMP; Extracellular Matrix; Ganglia, Parasympathetic; Isoquinolines; Laminin; Motor Neurons; Piperazines; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate

1989
The protein kinase C inhibitor H-7 inhibits concanavalin A induced T-lymphocyte activation.
    General pharmacology, 1989, Volume: 20, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Concanavalin A; In Vitro Techniques; Isoquinolines; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Mitogens; Piperazines; Protein Kinase C; Signal Transduction; Spleen; T-Lymphocytes; Thymidine

1989
Phosphorylation of T cell membrane proteins by activators of protein kinase C.
    Journal of immunology (Baltimore, Md. : 1950), 1988, Jun-15, Volume: 140, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Antigens, Differentiation, T-Lymphocyte; Concanavalin A; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Isoquinolines; Kinetics; Membrane Proteins; Phosphorylation; Piperazines; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate

1988
Down-regulation of beta-adrenergic receptors induced by mitogen activation of intracellular signaling events in lymphocytes.
    FEBS letters, 1995, May-08, Volume: 364, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Concanavalin A; Cyclic AMP; Down-Regulation; Genistein; In Vitro Techniques; Interleukin-2; Intracellular Fluid; Isoflavones; Isoquinolines; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Neuroimmunomodulation; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Receptors, Adrenergic, beta; Signal Transduction; Sulfonamides; T-Lymphocytes

1995
Dependence of thymocyte apoptosis on protein kinase C and phospholipase A2.
    FEBS letters, 1994, Jul-18, Volume: 348, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Calcimycin; Concanavalin A; DNA; Enzyme Activation; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Phospholipases A; Phospholipases A2; Piperazines; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thymus Gland

1994
A mechanism of vitamin E-enhanced active oxygen formation in concanavalin A-stimulated alveolar macrophage.
    Biochemistry and molecular biology international, 1993, Volume: 31, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calmodulin; Concanavalin A; Diglycerides; Enzyme Activation; Hypoxanthine; Hypoxanthines; Isoquinolines; Macrophages, Alveolar; Male; Oxygen; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides; Superoxides; Vitamin E; Xanthine Oxidase

1993
Natural killer and lectin-dependent cytotoxic activities of Kurloff cells: target cell selectivity, conjugate formation, and Ca++ dependency.
    Inflammation, 1996, Volume: 20, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium Channel Blockers; Cell Adhesion; Chelating Agents; Concanavalin A; Cytotoxicity, Immunologic; Enzyme Inhibitors; Esterases; Female; Guinea Pigs; Humans; Ionophores; Killer Cells, Natural; Magnesium; Mice; Microscopy, Electron, Scanning; Phytohemagglutinins; Protein Kinase C; Species Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Fluorescence depolarization as an early measure of T lymphocyte stimulation.
    Journal of immunological methods, 1997, Feb-14, Volume: 201, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Concanavalin A; Cytoplasm; Enzyme Inhibitors; Fluoresceins; Fluorescence Polarization; Humans; Lymphocyte Activation; Lymphocyte Count; Phosphatidylinositols; Phytohemagglutinins; Protein Kinase C; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors

1997
Augmented release of matrix metalloproteinase-9 by PKC activation in organotypic cultures of human breast cancer and adjacent normal breast tissue and fibroadenoma.
    The Chinese journal of physiology, 2004, Jun-30, Volume: 47, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Breast; Breast Neoplasms; Concanavalin A; Cycloheximide; Dactinomycin; Enzyme Activation; Enzyme Activators; Female; Fibroadenoma; Gelatin; Humans; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Organ Culture Techniques; Protease Inhibitors; Protein Biosynthesis; Protein Kinase C; Protein Synthesis Inhibitors; Transcription, Genetic

2004