1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with chlorine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (13.79) | 18.7374 |
| 1990's | 22 (75.86) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 2 (6.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hasuma, T; Matsui-Yuasa, I; Obayashi, M; Otani, S | 1 |
| Ganguly, NK; Gorowara, S; Mahajan, RC; Walia, BN | 1 |
| Hamilton, JR; Lembessis, P; MacLeod, RJ | 1 |
| Bryant, SH; Conte Camerino, D; Govoni, S; Tricarico, D | 1 |
| Hidaka, H; Nakamura, J; Nomura, Y; Tohda, M | 1 |
| Gershengorn, MC; Perlman, JH | 1 |
| Bryant, SH; Conte-Camerino, D | 1 |
| Barrett, KE; Dharmsathaphorn, K; Dinh, S; Kachintorn, U; Vajanaphanich, M; Vongkovit, P | 1 |
| Ganguly, NK; Khullar, M; Khurana, S; Panigrahi, D; Walia, BN | 1 |
| Churcher, Y; Gomperts, BD | 1 |
| Ganguly, NK; Garg, UC; Goyal, J; Walia, BN | 1 |
| Kajiyama, Y; Murayama, T; Nomura, Y; Takahashi, A | 1 |
| Franke, T; Glusa, E; Markwardt, F; Nilius, B | 1 |
| Browning, MD; Dunwiddie, TV; Hahner, LD; Harris, RA; Leidenheimer, NJ | 1 |
| Bollinger, DW; Franklin, CC; Kim, HD; Turner, JT | 1 |
| Kokubun, S; Saigusa, A | 1 |
| Endou, M; Hattori, Y; Kanno, M; Shirota, M | 1 |
| Lupu-Meiri, M; Oron, Y; Shapira, H | 1 |
| Dan'ura, T; Ishibashi, S; Kurokawa, T; Yamashita, A; Yanagiuchi, H | 1 |
| Lanius, RA; Pasqualotto, BA; Shaw, CA | 1 |
| Ganguly, NK; Kanwar, RK; Kumar, L; Panigrahi, D; Rakesh, J; Walia, BN | 1 |
| Abedin, MZ; Cates, JA; Giurgiu, DI; Moser, AJ; Roslyn, JJ; Saunders-Kirkwood, KD | 1 |
| Cupello, A; Hydén, H; Rapallino, MV | 1 |
| Fukura, H; Igarashi, M; Komiya, Y | 1 |
| Imada-Shirakata, Y; Kotera, T; Okuma, M; Ueda, S | 1 |
| Marunaka, Y; Niisato, N | 1 |
| Fuller, SJ; Georgiou, JG; Gu, BJ; Jursik, C; Sluyter, R; Wiley, JS | 1 |
| Akatsu, C; Hishinuma, S; Sato, Y; Shoji, M | 1 |
| Chakrabarti, MK; Hoque, KM; Koley, H; Sheikh, IA | 1 |
29 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and chlorine
| Article | Year |
|---|---|
Enhancement of spermidine/spermine N1-acetyltransferase activity by treatment with lithium chloride in Ehrlich ascites tumor cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetyltransferases; Animals; Blotting, Northern; Carcinoma, Ehrlich Tumor; Chlorides; Enzyme Induction; Isoquinolines; Lithium; Lithium Chloride; Piperazines; Protein Kinase Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Study on the mechanism of Giardia lamblia induced diarrhoea in mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Biological Transport; Calcimycin; Calcium; Chlorides; Diarrhea; Giardia lamblia; Intestinal Mucosa; Isoquinolines; Mice; Piperazines; Protein Kinase C; Sodium; Tetradecanoylphorbol Acetate | 1992 |
Effect of protein kinase C inhibitors on Cl- conductance required for volume regulation after L-alanine cotransport.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Absorption; Alanine; Alkaloids; Animals; Anions; Biological Transport; Cells, Cultured; Chlorides; Diglycerides; Electric Conductivity; Intestinal Mucosa; Intestines; Isoquinolines; Microvilli; Phorbol Esters; Piperazines; Protein Kinase C; Staurosporine | 1992 |
Modulation of rat skeletal muscle chloride channels by activators and inhibitors of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Chloride Channels; Chlorides; Isoquinolines; Male; Membrane Proteins; Muscles; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Tetrahydropapaveroline | 1991 |
Inhibitory effects of KN-62, a specific inhibitor of Ca/calmodulin-dependent protein kinase II, on serotonin-evoked C1-current and 36-C1-efflux in Xenopus oocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chloride Channels; Chlorides; Isoquinolines; Male; Membrane Proteins; Oocytes; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; Serotonin; Xenopus | 1991 |
Thyrotropin-releasing hormone stimulation of phosphoinositide hydrolysis desensitizes. Evidence against mediation by protein kinase C or calcium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Drug Tolerance; Glioma; Hydrolysis; Isoquinolines; Lithium; Lithium Chloride; Phosphatidylinositols; Piperazines; Pituitary Gland; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1991 |
Chloride channel regulation in the skeletal muscle of normal and myotonic goats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Membrane Permeability; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Electric Conductivity; Female; Goats; Ion Channels; Isoquinolines; Male; Membrane Potentials; Muscles; Myotonia; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Staurosporine; Tetrahydropapaveroline | 1991 |
Dual effects of a phorbol ester on calcium-dependent chloride secretion by T84 epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Calcium; Cell Line; Chlorides; Colon; Humans; Intestinal Mucosa; Isoquinolines; Osmolar Concentration; Piperazines; Protein Kinase Inhibitors; Rubidium; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Studies on the mechanism of Salmonella typhimurium enterotoxin-induced diarrhoea.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Calcimycin; Calcium; Chlorides; Diarrhea; Enterotoxins; Indomethacin; Intestinal Mucosa; Intestine, Small; Isoquinolines; Male; Piperazines; Prostaglandins; Protein Kinase C; Rats; Rats, Inbred Strains; Salmonella typhimurium; Sodium; Tetradecanoylphorbol Acetate; Verapamil; Water-Electrolyte Balance | 1991 |
ATP-dependent and ATP-independent pathways of exocytosis revealed by interchanging glutamate and chloride as the major anion in permeabilized mast cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amino Acid Sequence; Animals; Anions; beta-N-Acetylhexosaminidases; Calcium; Cations; Chlorides; Exocytosis; Glutamates; Glutamic Acid; Glyceryl Ethers; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoquinolines; Male; Mast Cells; Molecular Sequence Data; Peptide Fragments; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Secretory Rate; Signal Transduction | 1990 |
Differences between the mechanisms of action of heat-stable and heat-labile enterotoxins of Escherichia coli.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bacterial Toxins; Biological Transport, Active; Calcimycin; Calcium; Calmodulin; Chlorides; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Ileum; Isoquinolines; Mice; Piperazines; Protein Kinase C; Sodium; Tetradecanoylphorbol Acetate | 1990 |
Modes of inhibitory action of 4 beta-phorbol 12-myristate 13-acetate in thrombin-stimulated arachidonic acid release in intact and permeabilized platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Membrane Permeability; Chlorides; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Piperazines; Protein Kinase Inhibitors; Rabbits; Serotonin; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Pharmacological modification of mechanical and electrical responses of frog heart to thrombin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Barium; Barium Compounds; Calcium Channels; Chlorides; Electrophysiology; Enzyme Activation; Heart; In Vitro Techniques; Isoquinolines; Myocardial Contraction; Piperazines; Protein Kinase C; Rana esculenta; Tetradecanoylphorbol Acetate; Thrombin; Vasoconstriction | 1990 |
Phosphorylation-independent effects of second messenger system modulators on gamma-aminobutyric acidA receptor complex function.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Chlorides; Colforsin; Cyclic AMP; Edetic Acid; Isoquinolines; Mice; Mice, Inbred ICR; Muscimol; Phosphorylation; Piperazines; Protein Kinases; Pyridazines; Receptors, GABA-A; Second Messenger Systems | 1990 |
Vasoactive intestinal peptide stimulates active K+ transport and Na(+)-K(+)-Cl- cotransport in HT-29 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenocarcinoma; Amiloride; Biological Transport; Bumetanide; Carrier Proteins; Cell Line; Chlorides; Colonic Neoplasms; Humans; Isoquinolines; Kinetics; Norepinephrine; Ouabain; Piperazines; Potassium; Protein Kinase C; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide; Yohimbine | 1990 |
Protein kinase C may regulate resting anion conductance in vascular smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Chlorides; Electric Conductivity; Ion Channels; Isoquinolines; Muscle, Smooth, Vascular; Piperazines; Protein Kinase C; Time Factors | 1988 |
Dissociation of phosphoinositide hydrolysis and positive inotropic effect of histamine mediated by H1-receptors in guinea-pig left atria.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbamates; Chlorides; Electric Stimulation; Female; Guinea Pigs; Heart; Histamine; Hydrolysis; In Vitro Techniques; Isoquinolines; Lithium; Lithium Chloride; Male; Myocardial Contraction; Myocardium; Neomycin; Phenylcarbamates; Phorbol Esters; Phosphatidylinositols; Piperazines; Receptors, Histamine H1; Type C Phospholipases | 1989 |
Hemispheric asymmetry of rapid chloride responses to inositol trisphosphate and calcium in Xenopus oocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cell Compartmentation; Chlorides; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoquinolines; Oocytes; Piperazines; Protein Kinase C; Sugar Phosphates; Xenopus laevis | 1988 |
Characterization of heterologous desensitization of rat reticulocyte adenylate cyclase system.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Isoproterenol; Isoquinolines; Piperazines; Protein Kinases; Rats; Reticulocytes; Sodium Fluoride; Time Factors | 1987 |
A novel mechanism of AMPA receptor regulation: ionically triggered kinases and phosphatases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Chlorides; Glycerophosphates; Ibotenic Acid; In Vitro Techniques; Isoquinolines; Peptides; Phosphoric Monoester Hydrolases; Piperazines; Potassium; Protein Kinase Inhibitors; Protein Kinases; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Sodium; Tamoxifen; Vanadates | 1993 |
Calcium and protein kinase C play an important role in Campylobacter jejuni-induced changes in Na+ and Cl- transport in rat ileum in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcium; Calmodulin; Campylobacter Infections; Campylobacter jejuni; Chlorides; Cyclic AMP; Dantrolene; Diarrhea; Enzyme Activation; Ileum; In Vitro Techniques; Ion Transport; Isoquinolines; Male; Piperazines; Protein Kinase C; Rats; Rats, Wistar; Sodium; Tetradecanoylphorbol Acetate; Verapamil | 1995 |
Protein kinase C regulates prairie dog gallbladder ion transport.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Chlorides; Gallbladder; Ion Transport; Isoquinolines; Male; Phorbol Esters; Piperazines; Protein Kinase C; Sciuridae; Serotonin; Sodium | 1995 |
The increase in Cl- permeation across the Deiters' neuron membrane by GABA on its cytoplasmic side is abolished by protein kinase C (PKC) activators.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Membrane; Cell Membrane Permeability; Chlorides; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Male; Neurons; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Receptors, GABA-A; Vestibular Nucleus, Lateral | 1993 |
Signaling pathway downstream of GABAA receptor in the growth cone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Axons; Binding Sites; Calcium; Chlorides; Diazepam; Fetus; gamma-Aminobutyric Acid; GTPase-Activating Proteins; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Models, Neurological; Muscimol; Myristoylated Alanine-Rich C Kinase Substrate; Neurites; Picrotoxin; Prosencephalon; Proteins; Rats; Rats, Wistar; Receptors, GABA-A; Signal Transduction; Verapamil | 1996 |
Serotonin activates electrolyte transport via 5-HT2A receptor in rat colonic crypt cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Biological Transport; Calcium; Cells, Cultured; Chlorides; Colon; Egtazic Acid; Electrolytes; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Intestinal Mucosa; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin | 1997 |
Regulation of Cl- transport by IBMX in renal A6 epithelium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channel Blockers; Cell Line; Chloride Channels; Chlorides; Cyclic AMP; Cytosol; Enzyme Inhibitors; Epithelium; Ion Transport; Isoquinolines; Kidney; Kinetics; Nitrobenzoates; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Sulfonamides; Xenopus laevis | 1997 |
A quantitative method for routine measurement of cell surface P2X7 receptor function in leucocyte subsets by two-colour time-resolved flow cytometry.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; B-Lymphocytes; Barium; Biological Transport; Calcium; Chlorides; Enzyme Inhibitors; Ethidium; Flow Cytometry; Humans; Killer Cells, Natural; Leukocytes, Mononuclear; Monocytes; Potassium; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Reproducibility of Results; Sodium; T-Lymphocytes; Temperature | 2007 |
The affinity of histamine for Gq protein-coupled histamine H(1)-receptors is predominantly regulated by their internalization in human astrocytoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Astrocytoma; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chlorides; Clathrin; Endocytosis; G-Protein-Coupled Receptor Kinases; GTP-Binding Protein alpha Subunits, Gq-G11; Histamine; Histamine H1 Antagonists; Humans; Receptors, Histamine H1; Tumor Cells, Cultured; Zinc Compounds | 2012 |
The Epac1 signaling pathway regulates Cl- secretion via modulation of apical KCNN4c channels in diarrhea.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Cell Line, Tumor; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Diarrhea; Epithelial Cells; Guanine Nucleotide Exchange Factors; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Intestinal Mucosa; Mice; Microscopy, Confocal; Potassium Channel Blockers; Pyrazoles; rap GTP-Binding Proteins; rap1 GTP-Binding Proteins; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA Interference; Signal Transduction | 2013 |