Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and c.i. 42510

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with c.i. 42510 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hibell, AD; Humphrey, PP; Michel, AD; Thompson, KM; Xing, M1
Eschke, D; Hauschildt, S; Nieber, K; Wüst, M1
Clay, WC; Condreay, JP; Fonfria, E; Goodwin, JA; Levy, DS; Michel, AD; Roman, S; Smith, GD1
Chico, TJ; Hoggett, EE; Ogryzko, NV; Renshaw, SA; Solaymani-Kohal, S; Tazzyman, S; Wilson, HL1
Bin Dayel, A; Evans, RJ; Schmid, R1

Other Studies

5 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and c.i. 42510

ArticleYear
Complexities of measuring antagonist potency at P2X(7) receptor orthologs.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amiloride; Animals; Benzoxazoles; Buffers; Cations, Divalent; Cell Adhesion; Cells, Cultured; Drug Interactions; Enzyme Inhibitors; Ethidium; Fluorescent Dyes; Humans; Kinetics; Mice; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Quinolinium Compounds; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Rosaniline Dyes; Serum Albumin, Bovine; Sodium Chloride; Species Specificity; Temperature

2001
Pharmacological characterization of the P2X(7) receptor on human macrophages using the patch-clamp technique.
    Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 365, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Cells, Cultured; Electrophysiology; Humans; Macrophages; Monocytes; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Rosaniline Dyes

2002
Cloning and pharmacological characterization of the guinea pig P2X7 receptor orthologue.
    British journal of pharmacology, 2008, Volume: 153, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amino Acid Sequence; Animals; Cloning, Molecular; Guinea Pigs; Humans; Mice; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Rosaniline Dyes; Species Specificity; Suramin

2008
Zebrafish tissue injury causes upregulation of interleukin-1 and caspase-dependent amplification of the inflammatory response.
    Disease models & mechanisms, 2014, Volume: 7, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animal Fins; Animals; Caspase 1; Caspase Inhibitors; Conserved Sequence; Down-Regulation; Embryo, Nonmammalian; Humans; Inflammation; Interleukin-1beta; Leukocytes; NF-kappa B; Rosaniline Dyes; Signal Transduction; Up-Regulation; Zebrafish

2014
Mapping the Site of Action of Human P2X7 Receptor Antagonists AZ11645373, Brilliant Blue G, KN-62, Calmidazolium, and ZINC58368839 to the Intersubunit Allosteric Pocket.
    Molecular pharmacology, 2019, Volume: 96, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Allosteric Site; Amides; Binding Sites; Humans; Imidazoles; Indoles; Models, Molecular; Molecular Docking Simulation; Point Mutation; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; Rosaniline Dyes; Thiazoles

2019