Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and atrial natriuretic factor

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with atrial natriuretic factor in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's12 (75.00)18.2507
2000's1 (6.25)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jaiswal, RK1
Horio, T; Kohno, M; Murakawa, K; Takeda, T; Yasunari, K; Yokokawa, K1
Glembotski, CC; Hidaka, H; Irons, CE; Sei, CA1
Brown, JH; Glembotski, CC; Irons, CE; McDonough, PM; Sei, CA; Sprenkle, AB1
Haneda, M; Horide, N; Kajiwara, N; Kikkawa, R; Koya, D; Maeda, S; Shigeta, Y; Togawa, M1
Hashimoto, H; Ishida, A; Ito, T; Ogawa, K; Okumura, K; Satake, T; Tanahashi, T1
Jaiswal, N; Jaiswal, RK; Sharma, RK1
Glembotski, CC; McDonough, PM; Stella, SL1
Ruskoaho, H; Taskinen, P; Tóth, M2
Larsen, TH; Lillehaug, JR; Myking, O; Saetersdal, T1
Horio, T; Ikeda, M; Johchi, M; Kohno, M; Kurihara, N; Takeda, T; Yasunari, K1
Sjöholm, A1
Copenhagen, DR; Dixon, DB1
Choy, DF; da Cunha, V; Dole, WP; Halks-Miller, M; Johns, A; Li, W; Light, DR; Mahmoudi, M; Martin-McNulty, B; Schroeder, M; Vincelette, J; Wang, YX1
Guo, Y; Li, Q; Li, X; Liu, G; Xu, Y1

Other Studies

16 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and atrial natriuretic factor

ArticleYear
Endothelin inhibits the atrial natriuretic factor stimulated cGMP production by activating the protein kinase C in rat aortic smooth muscle cells.
    Biochemical and biophysical research communications, 1992, Jan-15, Volume: 182, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Cytosol; Endothelins; Enzyme Activation; Isoquinolines; Kinetics; Male; Muscle, Smooth, Vascular; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1992
Phorbol ester and atrial natriuretic peptide receptor response on vascular smooth muscle.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atrial Natriuretic Factor; Cyclic GMP; Dose-Response Relationship, Drug; Down-Regulation; Guanylate Cyclase; Isoquinolines; Muscle, Smooth, Vascular; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Tetradecanoylphorbol Acetate

1992
Protein kinase C and calmodulin kinase are required for endothelin-stimulated atrial natriuretic factor secretion from primary atrial myocytes.
    The Journal of biological chemistry, 1992, Mar-15, Volume: 267, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Natriuretic Factor; Cells, Cultured; Endothelins; Heart; Heart Atria; Isoquinolines; Kinetics; Myocardium; Nifedipine; Phorbol 12,13-Dibutyrate; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Sulfonamides

1992
The alpha-adrenergic stimulation of atrial natriuretic factor expression in cardiac myocytes requires calcium influx, protein kinase C, and calmodulin-regulated pathways.
    The Journal of biological chemistry, 1991, Aug-25, Volume: 266, Issue:24

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Atrial Natriuretic Factor; Calcium; Calmodulin; Cells, Cultured; Gene Expression; Heart; Hydrolysis; Isoquinolines; Myocardium; Nifedipine; Phenylephrine; Phosphatidylinositols; Piperazines; Protein Kinase C; Rats; Sulfonamides

1991
Dual mechanism of angiotensin II inhibits ANP-induced mesangial cGMP accumulation.
    Kidney international, 1991, Volume: 40, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Angiotensin II; Animals; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Glomerular Mesangium; Guanylate Cyclase; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate

1991
A calmodulin antagonist (W-7) and a protein kinase C inhibitor (H-7) have no effect on atrial natriuretic peptide release induced by atrial stretch.
    Life sciences, 1988, Volume: 42, Issue:17

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginine Vasopressin; Atrial Function; Atrial Natriuretic Factor; Bucladesine; Calmodulin; Dibutyryl Cyclic GMP; Heart; Heart Atria; Isoquinolines; Male; Phenylephrine; Physical Stimulation; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Sulfonamides

1988
Negative regulation of atrial natriuretic factor receptor coupled membrane guanylate cyclase by phorbol ester. Potential protein kinase C regulation of cyclic GMP signal in isolated adrenocortical carcinoma cells of rat.
    FEBS letters, 1988, Jan-18, Volume: 227, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenal Cortex Neoplasms; Animals; Atrial Natriuretic Factor; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Isoquinolines; Phosphorylation; Piperazines; Protein Kinase C; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Tetradecanoylphorbol Acetate

1988
Involvement of cytoplasmic calcium and protein kinases in the regulation of atrial natriuretic factor secretion by contraction rate and endothelin.
    The Journal of biological chemistry, 1994, Apr-01, Volume: 269, Issue:13

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Analysis of Variance; Animals; Animals, Newborn; Atrial Natriuretic Factor; Benzophenanthridines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cytoplasm; Endothelins; Fluorescent Dyes; Heart; Heart Atria; Indoles; Isoquinolines; Kinetics; Myocardial Contraction; Myocardium; Phenanthridines; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Phosphoproteins; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence

1994
Effects of genistein on cardiac contractile force and atrial natriuretic peptide secretion in the isolated perfused rat heart.
    European journal of pharmacology, 1994, May-02, Volume: 256, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Diltiazem; Drug Interactions; Genistein; Hemodynamics; Isoflavones; Isoquinolines; Male; Myocardial Contraction; Perfusion; Piperazines; Protein-Tyrosine Kinases; Radioimmunoassay; Rats; Rats, Sprague-Dawley

1994
Inhibition and down-regulation of protein kinase C in cultured atrial myocytes: effects on distribution of specific granules and secretion of atrial natriuretic peptide.
    Molecular and cellular endocrinology, 1993, Volume: 94, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Analysis of Variance; Animals; Atrial Natriuretic Factor; Cells, Cultured; Culture Media; Cycloheximide; Cytoplasmic Granules; Down-Regulation; Fluorescent Antibody Technique; Isoquinolines; Microscopy, Electron; Microtubules; Myocardium; Piperazines; Protein Kinase C; Radioimmunoassay; Rats; Staurosporine; Tetradecanoylphorbol Acetate

1993
Interaction of PDGF and natriuretic peptides on mesangial cell proliferation and endothelin secretion.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Atrial Natriuretic Factor; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Endothelins; Glomerular Mesangium; Isoquinolines; Kinetics; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Nitroprusside; Piperazines; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Thymidine; Transforming Growth Factor beta

1993
Relaxin stimulates atrial natriuretic peptide secretion in perfused rat heart.
    The Journal of endocrinology, 1996, Volume: 150, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart; Heart Rate; Isoquinolines; Male; Perfusion; Protein Kinase C; Rats; Rats, Sprague-Dawley; Relaxin; Staurosporine; Stimulation, Chemical; Sulfonamides

1996
Glucose stimulates islet beta-cell mitogenesis through GTP-binding proteins and by protein kinase C-dependent mechanisms.
    Diabetes, 1997, Volume: 46, Issue:7

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atrial Natriuretic Factor; Calcium Channel Blockers; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gallopamil; Glucose; GTP-Binding Proteins; Insulin; Insulin Secretion; Ionomycin; Ionophores; Islets of Langerhans; Pertussis Toxin; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella

1997
Metabotropic glutamate receptor-mediated suppression of an inward rectifier current is linked via a cGMP cascade.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Dec-01, Volume: 17, Issue:23

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Aminobutyrates; Animals; Atrial Natriuretic Factor; Benzoates; Cyclic GMP; Enzyme Inhibitors; Glutamic Acid; Glycine; Ictaluridae; Ion Channel Gating; Isoquinolines; Models, Neurological; Patch-Clamp Techniques; Photoreceptor Cells; Potassium Channels; Receptors, Metabotropic Glutamate; Second Messenger Systems; Thionucleotides

1997
Inhibition of Rho-kinase by fasudil attenuated angiotensin II-induced cardiac hypertrophy in apolipoprotein E deficient mice.
    European journal of pharmacology, 2005, Apr-11, Volume: 512, Issue:2-3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Apolipoproteins E; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Collagen Type III; Coronary Vessels; Dose-Response Relationship, Drug; Fibrosis; Gene Expression; Heart Rate; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Knockout; Myocardium; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; RNA, Messenger; Up-Regulation

2005
Inhibition of Rho-kinase ameliorates myocardial remodeling and fibrosis in pressure overload and myocardial infarction: role of TGF-β1-TAK1.
    Toxicology letters, 2012, Jun-01, Volume: 211, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atrial Natriuretic Factor; Blotting, Western; Collagen Type I; Collagen Type III; Fibrosis; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myosin Heavy Chains; Protein Kinase Inhibitors; Random Allocation; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Ventricular Remodeling

2012